| Links to Low Cost / No Cost Electrophysiology Software |
| for Synaptic Plasticity Related Software |
| Acquisition and Analysis |
| ACQ4 - by Luke Campagnola, Megan Kratz and Paul Manis | |
| Patch clamping and fluorescence imaging | |
| Uses National Instruments M- and X-Series boards | |
| AxoGraph - by Axograph Scientific (John Clements) | |
| Uses National Instruments M- and X-Series boards and Axon Digidata 132x boards | |
| AxoScope - by Molecular Devices (formerly Axon Instruments, can be freely downloaded) | |
| Use to view WinLTP generated gap-free Axon Binary Files (*.ABF). | |
| Use to extract sections in WinLTP generated generated gap-free Axon Binary Files (*.ABF) | |
| Uses Axon Digidata 132x boards | |
| DataPro - by the Spruston lab | |
| Electrophysiological data acquisition and analysis | |
| DClamp - by Kevin Staley and Waldemar Swiercs at the MGH Pediatric Epilepsy Center | |
|
Finally a good program for detecting epileptic
interical bursts and seizures that isn't protected by a
patent and run on an expensive box |
|
| Can analyze continuous gap-free Axon Binary Files that WinLTP generates | |
| Ephus - Neuroscience data acqusition | |
| Uses National Instruments M- and X-Series boards | |
| GePulse - by Michael Pusch at the Istituto di Biofisica CNR | |
| Uses National Instruments M- and X-Series boards | |
| jClamp - by Joseph Santos-Sacchi at SciSoft and Yale University | |
| Uses National Instruments M- and X-Series boards and Axon Digidata 132x boards | |
| mPhys - by Phil Larimer at Case Western Reserve | |
| A data acquisition and analysis program written in MatLab | |
| Uses National Instruments M- and X-Series boards | |
| NeuroMatic - by Jason Rothman at the University College London | |
| Is an IGOR program, recently updated | |
| Uses National Instruments M- and X-Series boards | |
| NeuroRighter - by John Ralston and others | |
| Very interesting program for recording from multi-electrode arrays | |
| Uses National Instruments M- and X-Series boards | |
| Open Ephys GUI - by Joshua Siegle, Jakob Voights and others | |
| Includes recording from large number of extracellular electrodes, spike analysis, and a lot more | |
| Uses OpenEphys and Itan boards, not National Instruments M- and X-Series boards | |
| Seft Sofware Suite - Electrophy 4 | |
| See "Introduction to Electrophysiological Methods and Instrumentation" by F. Bretschneider and J.R. de Weille | |
| Slice - by Lee, DiMattina, and Sanes at New York University | |
| Is an IGOR program | |
| Symphony | |
| A MATLAB based data acquisition system using Instrutech ITC-16, ITC-18, and ITC-1600 boards.. | |
| Vscope - by Daniel Wagenaar at the California Institute of Technology | |
| Imaging and electrophysiological data acquisition, written in Microsoft Visual C++ | |
| Uses National Instruments M- and X-Series boards | |
| WaveSurfer - developed at HHMI by the Svoboda, Magee, Spruston Jayaraman and Koyama labs. | |
| A pre-release patch-clamp electrophysiology software written in MatLab | |
| Uses National Instruments M- and X-Series boards | |
| WinWCP and WinEDR (Strathclyde Electrophysiology Suite) - by John Dempster | |
| Uses National Instruments M- and X-Series boards and Axon Digidata 132x boards | |
| Analysis Only |
| Chronux - by Partha Mitra's laboratory at Cold Spring Harbor Laboratories | |
| Digital signal processing for electrophysiological signals using MATLAB | |
| DataView - by Bill Heitler at the University of St. Andrews | |
| Use to detect spontaneous events in WinLTP generated generated gap-free Axon Binary Files | |
| Can detect spontaneous epileptic events | |
| Detected events can then be saved to ASCII txt files and reanalyzed with WinLTP | |
| Klustakwick - by Ken Harris at Rutgurs University | |
| Nest-O-Patch - by Viatcheslav Nesterov at the Institut für Zelluläre und Molekulare Physiologie, Erlangen | |
| Patch clamp analysis of HEKA and ASCII data files. | |
| NeuroScope and Klusters - by Hazan, Zugaro and Buzsáki at State Univ. of New Jersey, Newark | |
| MiniAnalysis Program - by Justin Lee of Synaptosoft | |
| Use to detect spontaneous events in WinLTP generated gap-free Axon Binary Files | |
| Can get decay constants for multiple spontaneous or triggered synaptic potentials | |
| Can do LTP analyses of Axon *.ABF files (and WinLTP Sweep files) | |
| StimFit - by Christoph Schmidt-Hieber | |
| Can get decay constants for synaptic potentials, event detection, power spectrum | |
| Can directly analyze single sweep WinLTP Sweep data files, and Axon Binary Files (*.ABF) | |
| Taro-Tools - by Taro Ishikawa | |
| A set of Igor Pro tools for neurophysiological analysis |
| WinLTP Reanalysis and bin2txtswps - by Alen Eapen, University of Toronto | |
| The WinLTP Reanalysis program is free. When coupled with Alen Eapen's free, open source bin2txtswps | |
| program (included inthe WinLTP distribution), WinLTP can reanalyze multi-sweep Axon ABF, Igor Pro IBW, | |
| and WinWCP binary files. | |
| WinLTPimport - by Clair Booth, University of Bristol | |
| WinLTPimport imports many WinLTP ASCII sweep files into a MATLAB program for performing reanalyses not | |
| done by WinLTP, WinLTPimport is free and open source and can be downloaded from the WinLTP website.. |
| Other Interesting Software |
| David Colquhoun's single channel analysis programs | |
| G-Clamp - Dynamic Clamp software - by Paul Kullmann, Diek Wheeler, Joshua Beacom and John Horn | |
| Uses National Instruments LabVIEW Real-Time, and M- and X-Series boards | |
| MATLAB Data Acquisition Tool Box | |
| Uses National Instruments M- and X-Series boards | |
| QUB - by the Sachs, Qin, Auerbach and Milescu labs at the State University of New York at Buffalo | |
| Used for single channel data acquisition and analysis | |
| Uses National Instruments M- and X-Series boards (can now do Dynamic Clamping at 6 usec sample intervals) | |
| StdpC - Dynamic Clamp sofware by Thomas Nowotny, David Samu and others | |
| Uses National Instruments M- and X-Series boards | |
| WinFluor - Fluorescence imaging software (Strathclyde Imaging Software) - by John Dempster | |
| Uses National Instruments M- and X-Series boards |