WinLTP
Version 3.00
Leading-Edge Features
Special Features
Special Analysis Features
Ordinary Features
Additional Features
Links to Low Cost / No Cost Electrophysiology Software
 
for Synaptic Plasticity Related Software

 

Acquisition and Analysis
      ACQ4 - by Luke Campagnola, Megan Kratz and Paul Manis
     Patch clamping and fluorescence imaging
     Uses National Instruments M- and X-Series boards
 
      AxoGraph - by Axograph Scientific (John Clements)
     Uses National Instruments M- and X-Series boards and Axon Digidata 132x boards
 
AxoScope - by Molecular Devices (formerly Axon Instruments, can be freely downloaded)
     Use to view WinLTP generated gap-free Axon Binary Files (*.ABF). 
     Use to extract sections in WinLTP generated generated gap-free Axon Binary Files (*.ABF)
     Uses Axon Digidata 132x boards
  
      DataPro - by the Spruston lab
     Electrophysiological data acquisition and analysis
 
DClamp - by Kevin Staley and Waldemar Swiercs at the MGH Pediatric Epilepsy Center
     Finally a good program for detecting epileptic interical bursts and seizures that isn't protected by a patent and
        run on an expensive box
     Can analyze continuous gap-free Axon Binary Files that WinLTP generates
   
       Ephus - Neuroscience data acqusition
       Uses National Instruments M- and X-Series boards
   
GePulse - by Michael Pusch at the Istituto di Biofisica CNR
     Uses National Instruments M- and X-Series boards
 
jClamp - by Joseph Santos-Sacchi at SciSoft and Yale University
     Uses National Instruments M- and X-Series boards and Axon Digidata 132x boards
 
mPhys - by Phil Larimer at Case Western Reserve 
     A data acquisition and analysis program written in MatLab
       Uses National Instruments M- and X-Series boards
  
NeuroMatic - by Jason Rothman at the University College London
     Is an IGOR program, recently updated
     Uses National Instruments M- and X-Series boards
   
NeuroRighter - by John Ralston and others
     Very interesting program for recording from multi-electrode arrays
     Uses National Instruments M- and X-Series boards
   
Open Ephys GUI - by Joshua Siegle, Jakob Voights and others
     Includes recording from large number of extracellular electrodes, spike analysis, and a lot more
     Uses OpenEphys and Itan boards, not National Instruments M- and X-Series boards
   
Seft Sofware Suite - Electrophy 4
    See "Introduction to Electrophysiological Methods and Instrumentation" by F. Bretschneider and J.R. de Weille
 
Slice - by Lee, DiMattina, and Sanes at New York University 
     Is an IGOR program
  
  Symphony
        A MATLAB based data acquisition system using Instrutech ITC-16, ITC-18, and ITC-1600 boards..
  Vscope - by Daniel Wagenaar at the California Institute of Technology
       Imaging and electrophysiological data acquisition, written in Microsoft Visual C++ 
       Uses National Instruments M- and X-Series boards
   
WaveSurfer - developed at HHMI by the Svoboda, Magee, Spruston Jayaraman and Koyama labs.
       A pre-release patch-clamp electrophysiology software written in MatLab
     Uses National Instruments M- and X-Series boards
  
WinWCP  and WinEDR (Strathclyde Electrophysiology Suite) - by John Dempster
     Uses National Instruments M- and X-Series boards and Axon Digidata 132x boards
           
              

Analysis Only
  Chronux - by Partha Mitra's laboratory at Cold Spring Harbor Laboratories
     Digital signal processing for electrophysiological signals using MATLAB
   
  DataView - by Bill Heitler at the University of St. Andrews
       Use to detect spontaneous events in WinLTP generated generated gap-free Axon Binary Files
       Can detect spontaneous epileptic events
       Detected events can then be saved to ASCII txt files and reanalyzed with WinLTP
  
Klustakwick - by Ken Harris at Rutgurs University
  
  Nest-O-Patch - by Viatcheslav Nesterov  at the Institut für Zelluläre und Molekulare Physiologie, Erlangen
        Patch clamp analysis of HEKA and ASCII data files. 
   
NeuroScope and Klusters - by Hazan, Zugaro and Buzsáki at State Univ. of New Jersey, Newark
  
MiniAnalysis Program - by Justin Lee of Synaptosoft
     Use to detect spontaneous events in WinLTP generated gap-free Axon Binary Files
     Can get decay constants for multiple spontaneous or triggered synaptic potentials
     Can do LTP analyses of Axon *.ABF files (and WinLTP Sweep files)
     
StimFit - by Christoph Schmidt-Hieber
     Can get decay constants for synaptic potentials, event detection, power spectrum
     Can directly analyze single sweep WinLTP Sweep data files, and Axon Binary Files (*.ABF)
   
  Taro-Tools - by Taro Ishikawa
        A set of Igor Pro tools for neurophysiological analysis
  
  WinLTP Reanalysis and bin2txtswps - by Alen Eapen, University of Toronto
       The WinLTP Reanalysis program is free.  When coupled with Alen Eapen's free, open source bin2txtswps
       program (included inthe WinLTP distribution),  WinLTP can reanalyze multi-sweep Axon ABF,  Igor Pro IBW,
       and WinWCP  binary files. 
  
  WinLTPimport - by Clair Booth, University of Bristol
       WinLTPimport imports many WinLTP ASCII sweep files into a MATLAB program for performing reanalyses not
       done by WinLTP,  WinLTPimport is free and open source and can be downloaded from the WinLTP website..

 

Other Interesting Software
  David Colquhoun's single channel analysis programs
   
  G-Clamp - Dynamic Clamp software - by Paul Kullmann, Diek Wheeler, Joshua Beacom and John Horn
       Uses National Instruments LabVIEW Real-Time, and M- and X-Series boards
   
MATLAB Data Acquisition Tool Box
     Uses National Instruments M- and X-Series boards  
  
QUB - by the Sachs, Qin, Auerbach and Milescu labs at the State University of New York at Buffalo
     Used for single channel data acquisition and analysis
     Uses National Instruments M- and X-Series boards (can now do Dynamic Clamping at 6 usec sample intervals)
   
  StdpC - Dynamic Clamp sofware by Thomas Nowotny, David Samu and others
       Uses National Instruments M- and X-Series boards
   
  WinFluor - Fluorescence imaging software  (Strathclyde Imaging Software) - by John Dempster
       Uses National Instruments M- and X-Series boards