WinLTP
Version 3.01
Leading-Edge Features
Special Features
Special Analysis Features
Ordinary Features
Additional Features
 
Papers using WinLTP and/or the LTP Program
(to 15 January, 2022)

WinLTP and the LTP Program has been used in at least 841 publications from labs in China, Finland, France, Germany, Israel, Italy, Japan, South Korea, Portugal, Russia, Saudi Arabia, Spain, Switzerland, UK and USA.

 

WinLTP

WinLTP has been used in at least 444 publications.

 

2022   WinLTP

 444. Cook SG, Rumian NL and Bayer KU (2022) Essential regulatory functions of CaMKII T286 phosphorylation in LTP and two distinct forms of LTD.  bioRxiv, /doi.org/10.1101/2022.01.03.474759.

443. Ferreira cb, Marttinen m, Coelho je, Paldanius KMA, Takalo M, Mäkinen P, Leppänen L, Miranda-Louren C, Fonseca-Gomes J, Tanqueiro SR, Vaza SH, Belo RF, Sebastião AM, Leinonen V, Soininen H, Pike I, Haapasalo A, Lopes LV and Hiltunen M (2021) S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5. Neurobiology of Disease, 163: 2022, 105603; doi.org/10.1016/j.nbd.2021.105603.

442. France G, Volianskis R, Ingram R, Bannister N, Rothärme R, Irvinea MW, Fanga G, Burnell ES, Sapkota K, Costa BM, Choprah BA, Dravid SM, Michael-Titus AT, Monaghan DT, Georgiou J, Bortolotto ZA, Jane DE, Collingridge GL and Volianskis A (2022) Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators. Neuropharmacology, 202:108840; doi.org/10.1016/j.neuropharm.2021.108840.

441. George H, Bashir ZI and Hussain S (2022) Impaired hippocampal NMDAR-LTP in a transgenic model of NSUN2-deficiency. Neurobiology of Disease, 163, February 2022, 105597; doi.org/10.1016/j.nbd.2021.105597.

440. Infantino R, Schiano C, Luongo L, Paino S, Mansueto G, Boccella S, Guida F, Ricciardi F, Iannotta M, Belardo C, Marabese I, Pieretti G, Serra N, Napoli C and Maione S (2022) MED1/BDNF/TrkB pathway is involved in thalamic hemorrhage-induced pain and depression by regulating microglia.  Neurobiology of Disease, 164:105611; doi.org/10.1016/j.nbd.2022.105611.

439. Jeong B, Baek JY, Koo J, Park S, Ryu YK, Kim KS, Zhang S, Chung CH, Dogan R, Choi HS, Um D, Kim TK, Lee WS, Jeong J, Shin WH, Lee JR, Kim NS and Lee DY (2021) Maternal exposure to polystyrene nanoplastics causes brain abnormalities in progeny.  Journal of Hazardous Materials, 426, 15 March 2022, 127815; doi.org/10.1016/j.jhazmat.2021.127815.

438. Potier B, Lallemant L, Parrot S, Huguet-Lachon A, Gourdon G, Dutar P and Gomes-Pereira M (2022) DM1 Transgenic Mice Exhibit Abnormal Neurotransmitter Homeostasis and Synaptic Plasticity in Association with RNA Foci and Mis-Splicing in the Hippocampus.  Int. J. Mol. Sci. 23:592; doi.org/10.3390/ijms23020592.

 

 

2021   WinLTP

437. Alhowail AH, Pinky PD, Eggert M, Bloemer J, Woodie LN, Buabeid MA, Bhattacharya S, Jasper SL, Bhattacharya D, Dhanasekaran M, Escobar M, Arnold RD and Suppiramaniam v (2021) Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficits. Heliyon 7:e07456; doi.org/10.1016/j.heliyon.2021.e07456.

436. Amici M, Lee Y, Pope RJP, Bradley CA, Cole A and Collingridge GL (2021) GSK‐3β regulates the synaptic expression of NMDA receptors via phosphorylation of phosphatidylinositol 4 kinase type IIα. European Journal of Neuroscience, 54:6815-6825; doi.org/10.1111/ejn.14841.

435. Amoateng P, Tagoe TA, Karikari TK, Kukuia KKE, Osei-Safo D, Woode E, Frenguelli BG and Kombian SB (2021) Synedrella nodiflora Extract Depresses Excitatory Synaptic Transmission and Chemically-Induced In Vitro Seizures in the Rat Hippocampus. Front Pharmacol, 12:610025; doi:10.3389/fphar.2021.610025.

434. Arrázola MS, Lira M, Quiroz G, Iqbal S, Eaton SL, Kline RA, Lamont DJ, Huerta H, Ureta G, Bernales S, Cárdenas JC, Cerpa W, Wishart TM, Court FA (2021) Necroptosis inhibition counteracts axonal degeneration, cognitive decline and key hallmarks of aging, promoting brain rejuvenation. bioRxiv, doi.org/10.1101/2021.11.10.468052.

433. Banks PJ, Warburton EC and Bashir ZI (2021) Plasticity in Prefrontal Cortex Induced by Coordinated Synaptic Transmission Arising from Reuniens/Rhomboid Nuclei and Hippocampus. Cerebral Cortex Communications, 2:tgab029; doi.org/10.1093/texcom/tgab029.

432. Barker G, Tran S, Gilroy K, Bashir Z and Warburton E (2021) Encoding and retrieval of associative recognition memory engage different sub-networks within a hippocampal-thalamo-cortical memory circuit. ResearchSquare, doi.org/10.21203/rs.3.rs-889826/v1.

431. Bertrand C, Deschamps C, Rabiant K, Peineau S, Antol J, Martinetti M, Naassila M, Vilpoux C and Pierrefiche O (2021) Patch‐Clamp Recording of Low Frequency Stimulation‐induced Long‐Term Synaptic Depression in Rat Hippocampus Slices During Early and Late neurodevelopment. Alcoholism: Clinical and Experimental Research, 45:351-364; doi.org/10.1111/acer.14516.

430. Boccella S, Guida F, Iannotta M, Iannotti FA, Infantino R, Ricciardi F, Cristiano C, Vitale RM, Amodeo P, Marabese I, Belardo C, de Novellis V, Paino S, Palazzo E, Calignano A, Di Marzo V, Maione S and Luongo L (2021) 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2-and H3 histamine autoreceptors. Mol Brain 14:28; doi.org/10.1186/s13041-020-00724-z.

429. Caruana DA and Dudek SM (2021) Adenosine Synaptic Depression A1 Receptor-Mediated in the Developing Hippocampal Area CA2. Latest Advances on Excitatory Synapse bIOLOGY, edited by Kimberly M. Huber, Pierre Paoletti, P. Jesper Sjöström. GoogleBook.com.

428. Carvajal FJ and Cerpa W (2021) Regulation of Phosphorylated State of NMDA Receptor by STEP61 Phosphatase after Mild-Traumatic Brain Injury: Role of Oxidative Stress. Antioxidants, 10:1575; doi.org/10.3390/antiox10101575.

427. Chang CW, Evans MD, Yu X, Yu GQ and Mucke L (2021) [HTML] Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony. Cell Reports, 37:109855; doi.org/10.1016/j.celrep.2021.109855.

426. Clennell B, Steward TGJ, Elley M, Shin E, Weston M, Drinkwater BW and Whitcomb DJ (2021) Transient ultrasound stimulation has lasting effects on neuronal excitability. Brain Stimulation, 14:217-225; doi.org/10.1016/j.brs.2021.01.003.

425. Cook SG, Buonarati OR, Coultrap SJ and Bayer KU (2021) CaMKII holoenzyme mechanisms that govern the LTP versus LTD decision. Science Advances, 7, Issue 16; doi:10.1126/sciadv.abe2300.

424. Daudin R, Marechal D, Golgolab R, Wang Q, Abe Y, Tsurugizawa T, Bourg N, Sartori M, Loe-Mie Y, Lipecka J, Guerrera C, McKenzie A, Potier B, Dutar P, Viard, J, Lepagnol-Bestel AM, Winkeler A, Uszynski I, Hindié V, Birling MC, Lindner L, Chevalier C, Pavlovic G, Reis M, Kranz H, Dupuis G, Lévêque-Fort S, Diaz J, Davenas, E, Dembele D, Atas-Ozcan H, Laporte J, Thibault-Carpentier C, Malissen B, Rain JC, Poupon C, Le Bihan D, Zhang B, Herault Y, Ciobanu L and Simonneau M (2021) BIN1 genetic risk factor for Alzheimer is sufficient to induce early structural tract alterations in entorhinal-hippocampal area and memory-related hippocampal multi-scale impairments. bioRxiv, doi.org/10.1101/437228.

423.  Davenport CM, Rajappa R, Katchan L, Taylor CR, Tsai MC, Smith CM, de Jong JW, Arnold DB, Lammel S and Kramer RH (2021) Relocation of an extrasynaptic GABAA receptor to inhibitory synapses freezes excitatory synaptic strength and preserves memory. Neuron, 109:123-134.e4; doi.org/10.1016/j.neuron.2020.09.037.

422. Dias L, Lopes CR, Gonçalves FQ, Nunes A, Pochmann D, Machado NJ, Tomé AR, Agostinho P and Cunha RA (2021) Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress. Front. Cell. Neurosci., doi.org/10.3389/fncel.2021.639322.

421. Eapen AV, Fernández-Fernández D, Georgiou J, Bortolotto ZA, Lightman S, Jane DE, Volianskis A and Collingridge GL (2021) Multiple roles of GluN2D-containing NMDA receptors in short-term potentiation and long-term potentiation in mouse hippocampal slices. Neuropharmacology, 201:108833; doi.org/10.1016/j.neuropharm.2021.108833.

420. Englund J, Haikonen J, Shteinikov V, Amarilla SP, Atanasova T, Shintyapina A, Ryazantseva M, Partanen J, Voikar V and Lauri SE (2021) Downregulation of kainate receptors regulating GABAergic transmission in amygdala after early life stress is associated with anxiety-like behavior in rodents. Transl Psychiatry 11:538; doi.org/10.1038/s41398-021-01654.

419. Fernandes MYD, Dobrachinski F, Silva HB, Lopes JP, Gonçalves FQ, Soares FAA, Porciúncula LO, Andrade GM, Cunha RA and Tomé AR (2021) Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices. Scientific Reports, 11:10488; doi.org/10.1038/s41598.

 418. Figueroa AG, Benkwitz C, Surges G, Kunz N, Homanics GE and Pearce RA (2021) Hippocampal β2-GABAA receptors mediate LTP suppression by etomidate and contribute to long-lasting feedback but not feedforward inhibition of pyramidal neurons. J Neurophysiol 126:1090–1100; doi:10.1152/jn.00303.2021.

417. Forte N, Boccella S, Tunisi L, Fernández-Rilo AC, Imperatore R, Iannotti FA, De Risi M, Iannotta M, Piscitelli F, Capasso R, De Girolamo P, De Leonibus E, Maione S, Di Marzo V and Cristino L (2021) Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice. Nat Commun 12:6137; doi.org/10.1038/s41467-021-26388-4.

516. Goodell DJ, Tullis JE and Bayer KU (2021) Young DAPK1 knockout mice have altered presynaptic function. Journal of Neurophysiology, doi.org/10.1152/jn.00055.2021.

415. Gomes JI, Jesus J, Macau R, Goncalves-Ribeiro J, Pinto S, Pina CC, Armada-Moreira A, Sebastião AM and Vaz SH (2021) Astrocytes are implicated in BDNF-mediated enhancement of hippocampal long-term potentiation.  bioRxiv, doi.org/10.1101/2021.03.30.437538.

414. González-Martín A, Moyano T, Gutiérrez DA, Carvaja FJ, Cerpa W, Hanley JC, Gutiérrez RA and Álvarez AR (2021) c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning. Progress in Neurobiology, 205:102122; doi.org/10.1016/j.pneurobio.2021.102122.

413.  Hofmann C, Sander A, Wang XX, Buerge M, Jungwirth B, Borgstedt L, Kreuzer M, Kopp C, Schorpp K, Hadian K, Wotjak CT, Ebert T, Ruitenberg M, Parsons C and Rammes G (2021) Inhalational Anesthetics Do Not Deteriorate Amyloid-β-Derived Pathophysiology in Alzheimer's Disease: Investigations on the Molecular, Neuronal, and Behavioral Level. Journal of Alzheimer's Disease, 84:1193-1218; doi:10.3233/JAD-201185.

412. Hsieh C, Tsokas P, Grau‐Perales A, Lesburguères E, Bukai J, Khanna K, Chorny J, Chung A, Jou C, Burghardt NS, Denny CA, Flores-Obando RE, Hartley BR, Valencia LMR, Hernández AI, Bergold PJ, Cottrell JE, Alarcon JM, Fenton AA and Sacktor TC (2021) Persistent increases of PKMζ in memory‐activated neurons trace LTP maintenance during spatial long‐term memory storage. European Journal of Neuroscience, 54:6795-6814; doi.org/10.1111/ejn.15137.

411. Jadhav KS, Bernheim AP, Aeschlimann L, Kirschmann G, Decosterd I, Hoffman AF, Lupica CR and Boutrel1 B (2021) Reversing anterior insular cortex neuronal hypoexcitability attenuates compulsive behavior in juvenile rats. bioRxiv, doi.org/10.1101/2021.10.28.466154.

410. Jeong WH, Kim WI, Lee JW, Park HK, Song MK, Choi IS and Han JY (2021) Modulation of Long-Term Potentiation by Gamma Frequency Transcranial Alternating Current Stimulation in Transgenic Mouse Models of Alzheimer's Disease. Brain Sci. 11:1532; doi.org/10.3390/brainsci11111532.

409. Kim SM, Zhang S, Park J, Sung HJ, Tran, Chung CH and Han IO (2021) REM Sleep Deprivation Impairs Learning and Memory by Decreasing Brain O-GlcNAc Cycling in Mouse. Neurotherapeutics, doi.org/10.1007/s13311-021-01094-7.

408. Koh W, Park M, Chun YE, Lee J, Shim HS, Park MG, Kim S, Kang H, Oh SJ, Woo J, Chun H, Lee S, Hong J, Feng J, Li Y, Ryu H, Cho J and Lee CJ (2021) Astrocytes render memory flexible. bioRxiv, doi.org/10.1101/2021.03.25.436945.

407. Kreis A, Desloovere J, Suelves N, Pierrot N, Yerna X, Issa F, Schakman O, Gualdani R, de Clippele M, Tajeddine N, Kienlen-Campard P, Raedt R, Octave JN and Gailly P (2021) Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission. Scientific Reports, 11:17600; doi.org/10.1038/s41598-021-97144-3.

406. Lecouflet P, Roux CM, Potier B, Leger M, Brunet E, Billard JM, Schumann-Bard P and Freret T (2021)  Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity.  Cerebral Cortex, 31:694–701; doi.org/10.1093/cercor/bhaa253.

405. Lee JH, Kim J, Noh S, Lee H, Lee SY, Mun JY, Park H and Chung WS (2021) Astrocytes phagocytose adult hippocampal synapses for circuit homeostasis. Nature, 590:612–617; doi.org/10.1038/s41586-020-03060-3.

404. Lee YY, Wang M, Son Y, Yang EJ, Kang MS, Kim MJ, Kim HS and Jo j (2021) Oat Extract Avenanthramide-C Reverses Hippocampal Long-Term Potentiation Decline in Tg2576 Mice. Molecules, 26:6105; doi.org/10.3390/molecules26206105.

403. Liu X, Zhang J, Mai C, Xiong Y, Lin ZJ, Jie YT, Mai JZ, Liu C, Xie MX and Zhou X (2021) The causal role of magnesium deficiency in the neuroinflammation, pain hypersensitivity and memory/emotional deficits in ovariectomized and aged female mice. J Inflamm Res, 14:6633–6656; doi: 10.2147/JIR.S330894.

402. McMillan KJ, Banks PJ, Hellel FLN, Carmichael RE, Clairfeuille T, Evans AJ, Heesom KJ, Lewis P, Collins BM, Bashir ZI, Henley JM, Wilkinson KA and Peter J Cullen (2021) Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2. eLife, doi: 10.7554/eLife.59432.

401. Moreira-de-Sá A, Gonçalves FQ, Lopes JP, Silva HB, Tomé AR, Cunha RA and Canas PM (2021) Motor Deficits Coupled to Cerebellar and Striatal Alterations in Ube3a m−/p+ Mice Modelling Angelman Syndrome Are Attenuated by Adenosine A 2A Receptor Blockade. Mol Neurobiol, 58:2543–2557; doi.org/10.1007/s12035-020-02275-9.

400. Nair JD, Braksator E, Yucel BP, Fletcher-Jones A, Seager R, Mellor JR, Bashir ZI, Wilkinson KA and Henley JM (2021) Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD. iScience, doi.org/10.1016/j.isci.2021.103029.

399. Park P, Georgiou J, Sanderson TM, Ko KH, Kang H, Kim J, Bradley CA, Bortolotto ZA, Zhuo M, Kaang BK and Collingridge gl (2021) PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus. Nature Communications, 12:413; doi.org/10.1038/s41467-020-20523-3.

398. Park P, Kang H, Georgiou J, Zhuo M, Kaang BK and Collingridge GL (2021) Further evidence that CP-AMPARs are critically involved in synaptic tag and capture at hippocampal CA1 synapses. Molecular Brain, 14:26;doi.org/10.1186/s13041-021-00737-2.

397. Paulo SL, Miranda-Lourenço C, Belo RF, Rodrigues RS, Fonseca-Gomes J, Tanqueiro SR, Geraldes V, Rocha I, Sebastião AM, Xapelli S and Diógenes MJ (2021) High Caloric Diet Induces Memory Impairment and Disrupts Synaptic Plasticity in Aged Rats. Current Issues in Molecular Biology, 43:2305–2319; doi.org/10.3390/cimb43030162.

396. Percelay S, Billard JM, Freret T, Andrieux A, Boulouard M and Bouet V (2021) Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia. International Journal of Molecular Science, 22:2644; doi.org/10.3390/ijms22052644.

395. Pereira MF, Amaral IM, Lopes C, Leitão C, Madeira D, Lopes JP, Gonçalves FQ, Canas PM, Cunha RA and Agostinho P (2021) l‐α‐aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory. The FASEB Journal,  Volume 35, Issue 8 e21726; doi.org/10.1096/fj.202100336R.

394. Regan P, Mitchell SJ, Kim SC, Lee Y, Yi JH, Barbati SA, Shaw C and Cho K (2021) Regulation of synapse weakening through interactions of the microtubule associated protein tau with PACSIN1. Journal of Neuroscience, 41:7162-7170; doi.org/10.1523/JNEUROSCI.3129-20.2021.

393. Roberts R, Wall M, Braren I, Dhillion K, Evans A, Dunne J, Nyakupinda S and Huckstepp R (2021) A new physiologically realistic and clinically relevant model of sleep apnoea for investigating it's effect as a comorbidity on neurodegenerative disease. ResearchSquare, doi.org/10.21203/rs.3.rs-829873/v1.

392. Ryu H, Cheon M and Chung CH (2021) The Impact of FKBP5 Deficiency in Glucocorticoid Receptor Mediated Regulation of Synaptic Transmission in the Medial Prefrontal Cortex. Neuroscience, 457:20-26; doi.org/10.1016/j.neuroscience.2020.12.020.

391. Salaka rj, Nair kp, Annamalai K, Srikumar BN and Kutty BM (2021) Enriched environment ameliorates chronic temporal lobe epilepsy‐induced behavioral hyperexcitability and restores synaptic plasticity in CA3–CA1 synapses in male Wistar rats. Journal of Neuroscience Research, 99:1646-1665; doi.org/10.1002/jnr.24823.

390. Sanders B, D'Andrea D, Collins MO, Rees E, Steward TGJ, Zhu Y, Chapman G, Legge SE, Pardiñas AF, Harwood AJ, Gray WP, O’Donovan MC, Owen MJ, Errington AC, Blake DJ, Whitcomb DJ, Pocklington AJ and Shin E (2021) DLG2 knockout reveals neurogenic transcriptional programs underlying neuropsychiatric disorders and cognition.  bioRxiv, doi.org/10.1101/2020.01.10.898676.

389. Sanderson JL, Freund RK, Gorski JA and Dell'Acqua ML (2021) β-Amyloid disruption of LTP/LTD balance is mediated by AKAP150-anchored PKA and Calcineurin regulation of Ca2+-permeable AMPA receptors. Cell Reports, 37:10978; doi.org/10.1016/j.celrep.2021.109786.

388. Seo HJ, Park JE, Choi SM, Kim T, Cho SH, Lee KH, Song WK, Song J, Jeong HS, Kim DH and Kim BC (2021) Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's Disease. Int. J. Mol. Sci. 22:698; doi.org/10.3390/ijms22020698.

387. Speck AE, Aguiar Jr AS, Ferreira SG, Silva HB, Tomé AR, Agostinho P and Cunha RA (2021) Exercise decreases aberrant corticostriatal plasticity in an animal model of l-DOPA-induced dyskinesia.  American Journal of Physiology, doi.org/10.1152/ajpregu.00295.2020.

386. Subhadeep D, Srikumar BN, Rao BSSS and Kutty BM (2021) Exposure to Short Photoperiod Regime Restores Spatial Cognition in Ventral Subicular Lesioned Rats: Potential Role of Hippocampal Plasticity, Glucocorticoid Receptors, and Neurogenesis. Mol Neurobiol, 58:4437–4459; doi.org/10.1007/s12035-021-02409-7.

385. Tan X, Liang Z, Li Y, Zhi Y, Yi L, Bai S, Forest KH, Nichols RA, Dong Y and Li QX (2021) Isoorientin, a GSK-3β inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice. Behavioural Brain Research, 398:112968; doi.org/10.1016/j.bbr.2020.112968.

384. Tanqueiro SR, Mouro FM, Ferreira CB, Freitas CF, Fonseca-Gomes J, Simões do Couto F, Sebastião AM, Dawson N and Diógenes MJ (2021) Sustained NMDA receptor hypofunction impairs brain-derived neurotropic factor signalling in the PFC, but not in the hippocampus, and disturbs PFC-dependent cognition in mice.  Journal of Psychopharmacology, doi.org/10.1177/02698811211008560.

383. Tian T, Qin X, Wang Y, Shi Y and Yang X (2021) 40 Hz Light Flicker Promotes Learning and Memory via Long Term Depression in Wild-Type Mice.  Journal of Alzheimer's Disease, 84:983-993, doi:10.3233/JAD-215212.

382. Vanaveski T, Molchanova S, Pham DD, Schäfer A, Pajanoja C, Narvik J, Srinivasan V, Urb M, Koivisto M, Vasar E, Timmusk T, Minkeviciene R, Eriksson O, Lalowski M, Taira T, Korhonen L, Voikar V and Lindholm D (2021) PGC-1α signaling increases GABA (A) receptor subunit α2 expression, GABAergic neurotransmission and anxiety-like behavior in mice. Front Mol Neurosci, 14:588230; doi: 10.3389/fnmol.2021.588230.

381. Van Den Herrewegen Y, Sanderson TM, Sahu S, De Bundel D, Bortolotto ZA and Smolders i (2021) Side-by-side comparison of the effects of Gq-and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the in the hippocampal CA1. Molecular Brain, 14:144; doi.org/10.1186/s13041-021-00856-w.

380. Wang M, Yoon G, Song J and Jo J (2021) Exendin-4 improves long-term potentiation and neuronal dendritic growth in vivo and in vitro obesity condition. Scientific Reports, 11:8326 (2021). https://doi.org/10.1038/s41598-021-87809-4.

379. Wang C, Yu Q, Li D, Sun N, Huang Y, Zhang YX and Zhou WX (2021) Reduced D-Serine Release May Contribute to Impairment of Long-Term Potentiation by Corticosterone in the Perforant Path-Dentate Gyrus.  Neurochemical Research, 46:2359–2375; doi.org/10.1007/s11064-021-03380-4.

378. Winkel F, Ryazantseva M, Voigt MB, Didio G, Lilja A, Pou ML, Steinzeig A, Harkki J, Englund J, Khirug S, Rivera C, Palva S, Taira T, Lauri SE, Umemori J and Castrén E (2021) Pharmacological and optical activation of TrkB in Parvalbumin interneurons regulate intrinsic states to orchestrate cortical plasticity.  Mol Psychiatry, doi.org/10.1038/s41380-021-01211-0.

377. Wright AM, Zapata A, Hoffman AF, Necarsulmer JC, Coke LM, Svarcbahs R, Richie CT, Pickel J, Hope BT, Harvey BK, and Lupica CR (2021) Effects of withdrawal from cocaine self-administration on rat orbitofrontal cortex parvalbumin neurons expressing cre recombinase: sex-dependent changes in neuronal function and unaltered serotonin signaling.   eNeuro. 8:ENEURO.0017-21.2021; doi: 10.1523/ENEURO.0017-21.2021.

376. Wolfe CIC, Hwang EK, Zapata A, Hoffman AF and Lupica CR (2021) Lateral habenula M2 muscarinic receptor control of neuronal activity and cocaine seeking behavior. bioRxiv, doi.org/10.1101/2021.07.24.453572.

375. Yi MH, Liu YU, Liu K, Chen T, Bosco DB, Zheng J, Xie m, Zhou L, Qu W and Wu LJ (2021) Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice. Brain, Behavior, and Immunity, 92:78-89; doi.org/10.1016/j.bbi.2020.11.030.

374. Yi MH, Liu YU, Umpierre AD, Chen T, Ying Y, Zheng J, Dheer A, Bosco DB, Dong H and Wu LJ (2021) Optogenetic activation of spinal microglia triggers chronic pain in mice. PLoS Biology, doi.org/10.1371/journal.pbio.3001154.

373. Zhang S, Cheon M, Park H, Kim T and Chung CH (2021) Interaction between glucocorticoid receptors and FKBP5 in regulating neurotransmission of the hippocampus. Neuroscience, doi.org/10.1016/j.neuroscience.2021.12.020.

 

 

2020   WinLTP

372. Aburawi SM, Buabeid MA, Auzi A, Mahmud MM, Buabeid MA and Altubuly RA (2020) Enhancing Spatial Memory Effects of Black Seed, Frankincense, and Ginger Extracts Using Albino Mice. Journal of Pharmacy and Pharmacology, 8:245-262; doi:10.17265/2328-2150/2020.08.004. 

371. Alhowail A, Zhang LX, Buabeid M, SHEN J-Z amd Suppiranam V (2020) Role of the purinergic P2Y2 receptor in hippocampal function in mice. European Review for Medical and Pharmacological Sciences,
2018; 22: 11858-11864.

370. Banks PJ, Warburton EC, Bashir ZI (2020) Plasticity in prefrontal cortex induced by coordinated nucleus reuniens and hippocampal synaptic transmission. bioRxiv, doi.org/10.1101/2020.07.11.197798.

369. Belo RF, Martins MLF, Shvachiy L, Costa-Coelho T, de Almeida-Borlido C, Fonseca-Gomes J, Neves V, Vicente Miranda H, Outeiro TF, Coelho JE, Xapelli S, Valente CA, Heras M, Bardaji E, Castanho MARB, Diógenes MJ and Sebastião AM (2020) The neuroprotective action of amidated-kyotorphin on amyloid β peptide-induced Alzheimer's disease pathophysiology. Front. Pharmacol., doi.org/10.3389/fphar.2020.00985.

368. Bodner O, Radzishevsky I, Foltyn VN, Touitou A, Valenta AC, Rangel IF, Panizzutti R, Kennedy RT, Billard JM and Wolosker H (2020) D-Serine signaling and NMDAR-mediated synaptic plasticity are regulated by system A-type of glutamine/D-serine dual transporters. Journal of Neuroscience, 40:489-6502; doi.org/10.1523/JNEUROSCI.0801-20.2020.

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366. Cheon M, Park H and Chung CH (2020) Protein kinase C mediates neuropeptide Y-induced reduction in inhibitory neurotransmission in the lateral habenula. Neuropharmacology, 180:108295, doi.org/10.1016/j.neuropharm.2020.108295.

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360. Govindarajulu M, Pinky PD, Steinke I, Bloemer J, Ramesh S, Kariharan T, Rella RT, Bhattacharya S, Dhanasekaran M, Suppiramaniam V and Amin RH (2020) Gut metabolite TMAO induces synaptic plasticity deficits by promoting endoplasmic reticulum stress. Front. Mol. Neurosci., doi.org/10.3389/fnmol.2020.00138.

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358. Kim WI, Han JY, Song MK, Park HK and Jo J (2020) Cognitive Function Improvement in Mouse Model of Alzheimer's Disease Following Transcranial Direct Current Stimulation. Brain Sciences,  10:547; doi.org/10.3390/brainsci10080547.

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356. Mennesson M, Orav E, Gigliotta A, Kulesskaya N, Saarnio S, Kirjavainen A, Kesaf S, Winkel F, Pou ML, Umemori J, Voikar V, Risbrough V, Partanen J, Castrén E, Lauri SE and Hovatta I (2020)  Kainate receptor auxiliary subunit NETO2-related cued fear conditioning impairments associate with defects in amygdala development and excitability.  eNeuro 2020; 10.1523/ENEURO.0541-19.2020, doi.org/10.1523/ENEURO.0541-19.2020.

355. Michaelides M, Miller ML, Egervari G, Primeaux SD, Gomez JL, Ellis RJ, Landry JA, Szutorisz H, Hoffman AF, Lupica CR, Loos RJF, ThanosPK, Bray GA, Neumaier JF, Zachariou B, Wang G-J, Volkow ND and Hurd YL (2020) Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity. Molecular Psychiatry, 25:2058–2069; doi: 10.1038/s41380-018-0120-7.

354. Moreira-de-Sá A, Gonçalves FQ, Lopes JP, Silva HB, Tomé AR, Cunha RA and Canas PM (2020) Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome.  Neurobiology of Disease, 146:105137; doi.org/10.1016/j.nbd.2020.105137.

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352. Oku S, Feng H, Connor S, Toledo A, Zhang P, Zhang Y, Thoumine O, Zhang C and Craig AM (2020) Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity  eLife, 2020;9:e58668, DOI: 10.7554/eLife.58668.

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350. Park K and Chung CH  (2020)  Differential Alterations in Cortico-Amygdala Circuitry in Mice with Impaired Fear Extinction. Molecular Neurobiology, volume57:pages710–721, doi.org/10.1007/s12035-019-01741-3.

349. Petrisko TJ, Bloemer J, Pinky PD, Srinivas S, Heslin RT, Du Y, Setti SE, Hong H, Suppiramaniam V, Konat GW and Reed MN (2020) Neuronal CXCL10/CXCR3 axis mediates the induction of cerebral hyperexcitability by peripheral viral challenge. Front. Neurosci., doi.org/10.3389/fnins.2020.00220.

348. Ploux E, Bouet V, Radzishevsky I, Wolosker H, Freret T and Billard J-M (2020) Serine racemase deletion affects the excitatory/inhibitory balance of the hippocampal CA1 network. Int. J. Mol. Sci., 21:9447; doi.org/10.3390/ijms21249447.

347.  Poirel O, Mamer LE, Herman MA, Arnulf-empcke M, Kervern M, Potier B, Miot M, Wang J, Favre-Besse F-C, Brabet I, Laras Y, Bertrand H-O, Acher F, Pin J-F, Puel J-l, Giros B, Epelbaum J, Rosenmund C, Dutar P, Daumas S, Mestikawy SE and Pietrancosta N  (2020)  LSP5-2157 a new inhibitor of vesicular glutamate transporters. Neuropharmacology, 164:107902; doi.org/10.1016/j.neuropharm.2019.107902.

346. Privitera L, Morè L, Cooper DD, Richardson P, Tsogka M, Hebenstreit D, Arthur JSC and Frenguelli BG (2020) Experience recruits MSK1 to expand the dynamic range of synapses and enhance cognition.  Journal of Neuroscience, 40:4644–4660; doi.org/10.1523/JNEUROSCI.2765-19.2020.

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344. Rei N, Rombo DMF, Ferreira MF, Baqi Y, Müller CE, Ribeiro JA, Sebastião AM and Vazab SH (2020) Hippocampal synaptic dysfunction in the SOD1G93A mouse model of Amyotrophic Lateral Sclerosis: Reversal by adenosine A2AR blockade. Neuropharmacology, 171:108106, doi.org/10.1016/j.neuropharm.2020.108106.

343. Ryazantseva M, Englund J, Shintyapina A, Huupponen J, Shteinikov V, Pitkanen A, Partanen JM and Lauri SE (2020) Kainate receptors regulate development of glutamatergic synaptic circuitry in the rodent.amygdala. eLife, 2020;9:e52798 DOI: 10.7554/eLife.52798.

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341. Ryu HH, Kang M, Hwang KD, Jang HB, Kim SJ and Lee YS (2020) Neuron type-specific expression of a mutant KRAS impairs hippocampal-dependent learning and memory. Scientific Reports, 10:17730; doi.org/10.1038/s41598-020-74610-y.

340. Sa de Almeida J, Vargas M, Fonseca-Gomes J, Tanqueiro SR, Belo RF, Miranda-Lourenço C, Sebastião AM, Diógenes MJ and Pais TF (2020) Microglial Sirtuin 2 Shapes Long-Term Potentiation in Hippocampal Slices. Front. Neurosci., doi.org/10.3389/fnins.2020.00614.

339.  Sanders B, D’Andrea D, Collins MO, Rees E, Steward TGJ, Zhu Y, Chapman G, Legge SE, Pardiñas AF, Harwood AJ, Gray WP, O’Donovan MC, Owen MJ, Errington AC, Blake DJ, Whitcomb DJ, Pocklington AJ and Shin E  (2020)  Synaptic protein DLG2 controls neurogenic transcriptional programs disrupted in schizophrenia and related disorders.  bioRxiv, doi.org/10.1101/2020.01.10.898676.

338. Santa-Marinha L, Castanho I, Silva RR, Bravo FV, Miranda AM, Meira T, Morais-Ribeiro R, Marques F, Xu Y, Point du Jour K, Wenk W, Chan RB, Di Paolo G, Pinto V amd Oliveira TG (2020) Phospholipase D1 ablation disrupts mouse longitudinal hippocampal axis organization and functioning. Cell Reports, 30:4197-4208.e6, doi.org/10.1016/j.celrep.2020.02.102.

337. Socodato R, Portugal CC, Canedo T, Rodrigues A, Almeida TO, Henriques JF, Vaz SH, Magalhaes J, Silva CM, Baptista FI, Alves RL, Coelho-Santos V, Silva AP, Paes-de-Carvalho R, Magalhaes A, Brakebusch C, Sebastiao AM, Summavielle T, Ambrosio AF and Relvas JB (2020) Microglia dysfunction caused by the loss of Rhoa disrupts neuronal physiology and leads to neurodegeneration. Cell Reports, doi.org/10.1016/j.celrep.2020.107796.

336. Song J, Wang M, Yoon G and J (2020) Exendin-4 Improves Long-Term Potentiation and Neuronal Dendritic Growth in High-Fat Diet Mice and Neurons Under Metabolic Imbalance Conditions. Research Square, doi.org/10.21203/rs.3.rs-109387/v1. 

335. Urru M, Muzzi M, Coppi E, Ranieri G, Buonvicino D, Camaioni E, Coppini R, Pugliese AM, Tanaka B, Estacion M, Waxman SG, Dib-Hajj SD and Chiarugi A (2020) Dexpramipexole blocks Nav1.8 sodium channels and provides analgesia in multiple nociceptive and neuropathic pain models. Pain, 161:831-841;  doi: 10.1097/j.pain.0000000000001774.

334. Wall M, Hill E, Huckstepp R, Barkan K, Deganutti G, Leuenberger M, Preti B, Winfield I, Wei H, Imlach W, Dean E, Hume C, Hayward S, Oliver J, Zhao F-Y, Spanswick D, Reynolds CA, Lochner M, Ladds G and Frenguelli BG (2020) A biased adenosine A1R agonist elicits analgesia without cardiorespiratory depression. bioRxiv, doi.org/10.1101/2020.04.04.023945.

333. Wang M, Ramasamy VS, Kang HK and Jo j (2020) Oleuropein promotes hippocampal LTP via intracellular calcium mobilization and Ca2+-permeable AMPA receptor surface recruitment. Neuropharmacology, 176:108196, doi.org/10.1016/j.neuropharm.2020.108196.

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328. Amici M, Lee Y, Pope RJP and Collingridge GL (2019)  GSK-3β regulates the synaptic expression of NMDA receptors via phosphorylation of phosphatidylinositol 4 kinase type IIα.  bioRxiv, doi: https://doi.org/10.1101/841676.

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321. Cheon M, Park H, Rhim H and Chung CH  (2019)  Actions of Neuropeptide Y on Synaptic Transmission in the Lateral Habenula.  Neuroscience, 410:183-190.

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319.  Clements L and Harvey J  (2019)  Activation of oestrogen receptor a induces a novel form of LTP at hippocampal temporoammonic-CA1 synapses.  Brit. J. Pharmacol., doi.org/10.1111/bph.14880.

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315.  Farmer LK, Rollason R, Whitcomb DJ, Ni L, Goodliff A, Lay AC, Birnbaumer L, Heesom KJ, Xu S-Z, Saleem MS and Welsh HI  (2019)  TRPC6 binds to and Activates Calpain, Independent of Its Channel Activity, and Regulates Podocyte Cytoskeleton, Cell Adhesion, and Motility.  JASN, 30:1910-1924; doi.org/10.1681/ASN.2018070729.

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311.  Hoeller AA, Lach G, Costa APR, Walz R, Bortolotto ZA and De Lima TCM  (2019)  Hippocampus-dependent fear conditioning is not sensitized by muscarinic receptor activation following systemic injection of pilocarpine.  Neurology, Psychiatry and Brain Research, 34:44-49; doi.org/10.1016/j.npbr.2019.10.004

310.  Huang Y, Li D, Cheng B, Liu G, Zhang Y-X and Zhou W-X  (2019)  Active fraction combination from Liuwei Dihuang decoction (LW-AFC) ameliorates corticosterone-induced long-term potentiation (LTP) impairment in mice in vivo.  Journal of Ethnopharmacology, 236:147-154.

309.  Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh S-C, Hoffer BJ, Becker RE, Pick CG, Lupica CR and Greig NH  (2019)  (-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice. Neurobiology of Disease, 130:104528; doi.org/10.1016/j.nbd.2019.104528.

308.  Liu Q, Sinnen BL, Boxer EE, Schneider MW, Grybko MJ, Buchta WC, Gibson ES, Wysoczynski CL, Ford CP, Gottschalk A, Aoto J, Tucker CL and Kennedy MJ  (2019)  A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission.  Neuron, 101:863-875.e6; doi.org/10.1016/j.neuron.2019.01.002.

307. Lopes JP, Pliássova A and Cunha RA  (2019)  The physiological effects of caffeine on synaptic transmission and plasticity in the mouse hippocampus selectively depend on adenosine A1 and A2A receptors.  Biochem. Pharmacol., 166:313-321.

306.  Marinha LS, Castanho I, Silva RB, Bravo FV, Miranda AM, Xu Y, Point du Jour K, Wenk M, Chan RM, Di Paolo G, Pinto V and Oliveira TG  (2019)  Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning.  Cell Reports.

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304. Morató X, Gonçalves FQ, Lopes JP, Jauregui O, Soler C, Fernández-Dueñas V, Cunha RA and Ciruela F  (2019)  Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37‐deficient mice.  J. Neurochem., doi.org/10.1111/jnc.14653.

303.  Nakamura Y, Dryanovski DI, KimuraY, Jackson SN, Woods AS, Yasui Y, Tsai S-Y, Patel S, Covey DP, Su T-P and Lupica CR  (2019)  Cocaine-induced endocannabinoid signaling mediated by sigma-1 receptors and extracellular vesicle secretion.  eLife 2019;8:e47209; doi.org/10.7554/eLife.47209.

302.  Ochiishi T, Kaku M, Kiyosue K, Doi M, Urabe T, Hattori N, Shimura H and Ebihara T  (2019)  New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid ß oligomers.  Scientific Reports, 9:17368; doi.org/10.1038/s41598-019-53415-8,

301. Oh ST, Liu QF, Jeong HJ, Lee S, Samidurai M, Jo J, Pak SC, Park H-J, Kim J and Jeon S (2019) Nasal Cavity Administration of Melanin-Concentrating Hormone Improves Memory Impairment in Memory-Impaired and Alzheimer’s Disease Mouse Models. Molecular Neurobiology, 56:8076–8086.

300.  Orav E, Ilona Dowavic, Johanna Huupponen, Tomi Taira & Sari E. Lauri  (2019)  NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation.  Molecular Neurobiology, 56:7473–7489; doi.org/10.1007/s12035-019-1612-4.

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298.  Park P, Sanderson TM, Bortolotto ZA, Georgiou J, Zhuo,, M, Kang B-K and Collingridge, GL  (2019)  Differential sensitivity of three forms of hippocampal synaptic potentiation to depotentiation.  Mol Brain 12, 30 https://doi.org/10.1186/s13041-019-0451-6

297.  Pickford J, Apps R and Bashir ZI  (2019)  Muscarinic Receptor Modulation of the Cerebellar Interpositus Nucleus In Vitro.  Neurochemical Research, 44:627–635.

296.  Pierrot N, Ris L, Stancu I-C, Doshina A, Ribeiro F, Tyteca D, Baugé E, Lalloyer F, Malong L, Schakman O, Leroy K, Kienlen-Campard P, Gailly P, Brion J-P, Dewachter I, Staels B and Octave J-N   (2019)  Sex-regulated gene dosage effect of PPARα on synaptic plasticity.  Life Science Alliance, DOI10.26508/lsa.201800262.

295.  Pinto-Duarte A, Roberts AJ, Ouyang K, Sejnowski TJ  (2019)  Impairments in remote memory caused by the lack of Type 2 IP3 receptors.  Glia, doi.org/10.1002/glia.23679.

294.  Privitera L, Hogg EL, Gaestel M, Wall MJ and Corrêa SAL  (2019)  The MK2 cascade regulates mGluR-dependent synaptic plasticity and reversal learning.  Neuropharmacology, 155:121-130; doi.org/10.1016/j.neuropharm.2019.05.024.

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292. Ryazantseva M, Englund J, Shintyapina A, Huupponen J, Pitkänen A, Partanen JM and Lauri SE  (2019)   Kainate-type of glutamate receptors regulate wiring of intrinsic glutamatergic connectivity in the amygdala.  bioRxiv, doi.org/10.1101/753103.

291.  Ruhl DA, Bomba-Warczak E, Watson ET, Bradberry MM, Peterson TA, Basu T, Frelka A, Evans CS, Briguglio JS, Basta T, Stowell MHB, Savas JN, Roopra A, Pearce RA, Piper RC and Chapman ER  (2019)  Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways.  Nature Communications, 10:3532; doi.org/10.1038/s41467-019-11459-4.

290.  Ryu H-H, Kim TH, Kim J-W, Kang M, Park P, Kim YG, Kim H, Ha J, Choi JE, Lee J, Lim C-S, Kim C-H, Kim SJ, Silva AJ, Kaang B-K and Lee Y-S  (2019)  Excitatory neuron–specific SHP2-ERK signaling network regulates synaptic plasticity and memory.  Science Signaling 12, eaau5755.

289. Schiffino FL, Siemian JN, Petrella M, Laing BT, Sarsfield S, Borja CB, Gajendiran A, Zuccoli ML and Aponte Y (2019) Activation of a lateral hypothalamic-ventral tegmental circuit gates motivation.  PLoS One, 14(7):e0219522, doi: 10.1371/journal.pone.0219522

288. Tsokas P, Rivard B, Hsieh C, Cottrell JE, Fenton AA and Sacktor TC (2019)  Antisense Oligodeoxynucleotide Perfusion Blocks Gene Expression of Synaptic Plasticity-related Proteins without Inducing Compensation in Hippocampal Slices.  Bio Protoc. 9:e3387, doi:10.21769/BioProtoc.3387.

287. van Diggelen F, Hrle D, Apetri M, Christiansen G, Rammes G, Tepper A and Otzen DE  (2019)  Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation.  PLOS|ONE, doi.org/10.1371/journal.pone.0213663.

286.  Wallach J, Colestock T, Agramunt J, Claydon MDB, Dybek M, Filemban N, Chatha M, Halberstadt A;. Brandt SD, Lodge D, Bortolotto ZA and Adejare A  (2019)  Pharmacological characterizations of the 'legal high' fluorolintane and isomers. Eur. J. Pharmacol., 857:172427, doi.org/10.1016/j.ejphar.2019.172427.

285.  Wallach J, Kavanagh PV, Mclaughlin G, Morris N, Power JD, Elliott SP, Mercier MS, Lodge D, Morris H, Dempster NM and Brandt SD  (2019)  Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers. researchonline.ljmu.ac.uk/id/eprint/3408/.

284. Wang M, Ramasamy VS, Samidurai M and Jo J (2019)  Acute restraint stress reverses impaired LTP in the hippocampal CA1 region in mouse models of Alzheimer’s disease.  Scientific Reports, 9: 10955; doi.org/10.1038/s41598-019-47452-6.

283.  EG Wheatley, E Albarran, CW White III, G BierI, Sanchez-Diaz C, Pratt K, Snethlage CE, Ding JB and Villeda SA  (2019)   Neuronal O-GlcNAcylation improves cognitive function in the aged mouse brain.  Current Biology, doi.org/10.1016/j.cub.2019.08.003.

282.  Wild AR, Sinnen BL, Dittmer PJ, Kennedy MJ, Sather WA and Dell’Acqua ML  (2019)  Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma.  Cell Reports, 26:3537-3550.e4; doi.org/10.1016/j.celrep.2019.03.005.

281.  Zhou L-J, Peng J, Xu Y-N, Zeng W-J, Zhang J, Wei X, Mai C-L, Lin C-J, Liu Y, Murugan M, Eyo UB, Umpierre AD, Xin W-J, Chen T, Li M, Wang H, Richardson JR, Tan Z, Liu X-J and Wu L-J  (2019)  Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain. Cell Reports, 27:3844-3859.e6.

 

 

2018   WinLTP

280.  Al-Osta I, Mucha M, Pereda D and Piqué-Gili P  (2018)  Imaging calcium in hippocampal presynaptic terminals with a ratiometric calcium sensor in a novel transgenic mouse.  Front. Cell. Neurosci., 12:209; doi: 10.3389/fncel.2018.00209.

279.  Amorim IS, Kedia S, Kouloulia S, Simbriger K, Gantois I, Jafarnejad SM, Li Y, Kampaite A, Pooters T, Romano N and Gkogkas CG (2018)  Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation.  J. Neuroscience, 38:2118–2133, doi.org/10.1523/JNEUROSCI.2673-17.2018.

278.  Androuin A, Potier B, Nägerl UV, Cattaert D, Danglot L, Thierry M, Youssef I, Triller A, Duyckaerts C, El Hachimi KH, Dutar P, Delatour B and Marty S  (2018)  Evidence for altered dendritic spine compartmentalization in Alzheimer's disease and functional effects in a mouse model.  Acta Neuropathologica, doi.org/10.1007/s00401-018-1847-6.

 277.  Audrain M, Souchet B, Alves S, Fol R, Viode A, Haddjeri A, Tada S, Orefice NS, Joséphine C, Bemelmans A-P,  Delzescaux T, Déglon N, Hantraye P, Akwa Y, Becher F, Billard J-M,, Potier B, Dutar P, Cartier N and Braudeau J  (2018)βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease.  Cerebral Cortex, 28: 3976–3993.

276. Bian C, Huang Y, Zhu H, Zhao Y, Zhao J, Zhang J  (2018)  Steroid Receptor Coactivator-1 Knockdown Decreases Synaptic Plasticity and Impairs Spatial Memory in the Hippocampus of Mice.  doi.org/10.1016/j.neuroscience.2018.02.034.

275.  Billard JM and Freret T  (2018)  Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA 3/CA 1 synapses.  J. Neurochem., 147:514-525; doi.org/10.1111/jnc.14586.

274.  Buonvicino D, Felici R, Ranieri G and Caramelli R  (2018)  Effects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS Mice. Neuroscience, 379:228-238; doi.org/10.1016/j.neuroscience.2018.03.022.

273.  Carvajal FJ, Mira RG, Rovegno M, Minniti AM and Cerpaa W  (2018)  Age-related NMDA signaling alterations in SOD2 deficient mice.  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (in press); doi.org/10.1016/j.bbadis.2018.03.019.

272.  Choi JE, Kim S, Lee J and Kim K  (2018)  Circadian Regulation by REV-ERBa Mediates Hippocampal E-LTP in a Time-dependent Manner.  Exp. Neurobiol., 27:344-349; doi.org/10.5607/en.2018.27.5.344.

271. Datunashvili1 M, Chaudhary R, Zobeiri M, Lüttjohann A, Mergia E, Baumann A, Balfanz S, Budde B, van Luijtelaar G, Pape H-C, Koesling D and Budde T  (2018)  Modulation of hyperpolarization-activated inward current and thalamic activity modes by different cyclic nucleotides.  Front. Cell. Neurosci., doi.org/10.3389/fncel.2018.00369 .

270.  Daudin R, Marechal D, Wang Q, Abe Y, Bourg N, Sartori M, Loe-Mie Y, Lipecka J, Guerrera C, McKenzie A, Potier B, Dutar P, Viard J, Lepagnol-Bestel A-M, Winkeler A, Hindie V, Birling M-C, Lindner L, Chevalier C, Pavlovic G, Reiss M, Kranz H, Dupuis G, Leveque-Fort S, Diaz J, Davenas E, Dembele D, Laporte J, Thibault-Carpentier C, Malissen B, Rain J-C, Ciobanu L, Le Bihan D, Zhang B, Herault Y and Simonneau M  (2018)  BIN1 genetic risk factor for Alzheimer is sufficient to induce early structural tract alterations in entorhinal cortex-dentate gyrus pathway and related hippocampal multi-scale impairments.  BioRxiv, doi.org/10.1101/437228.

269.  Domenici MR, Chiodi V, Averna M, Armida M, Pèzzola A, Pepponi R, Ferrante A, Bader M, Fuxe K and Popoli P (2018)  Neuronal adenosine A2A receptor overexpression is neuroprotective towards 3-nitropropionic acid-induced striatal toxicity: a rat model of Huntington's disease.  Purinergic Signalling, 14:235–243; doi.org/10.1007/s11302-018-9609-4.

268.  Dutar P and Potier B  (2018)  Susceptibility to Aßo and TBOA of LTD and Extrasynaptic NMDAR-Dependent Tonic Current in the Aged Rat Hippocampus.  Neurochem. Res. doi.org/10.1007/s11064-018-2677-6.

267.  Hall J and Frenguelli BG  (2018)  The combination of ribose and adenine promotes adenosine release and attenuates the intensity and frequency of epileptiform activity in hippocampal slices: Evidence for the rapid depletion of cellular ATP during electrographic seizures.  J. Neurochem., 147,:178-189; doi.org/10.1111/jnc.14543.

266.  Hundehege P, Fernandez-Orth J, Römer P, Ruck T, Müntefering T, Eichler S, Cerina M, Epping L, Albrecht S, Menke AF, Birkner K, Göbel K, Budde T, Zipp F, Wiendl H, Gorji A, Bittner S and Meuth SG  (2018)  Targeting Voltage-Dependent Calcium Channels with Pregabalin Exerts a Direct Neuroprotective Effect in an Animal Model of Multiple Sclerosis.  Neurosignals, 26:77–93; doi.org/10.1159/000495425.

265.  Ingram R, Kang H, Lightman S, Jane DE, Bortolotto ZA, Collingridge GL, Lodge D and Volianskis A  (2018)  Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity.  Neuropharmacology, 142:30-40; doi.org/10.1016/j.neuropharm.2018.06.008.

264.  Kerkhofs A, Canas PM, Timmerman AJ, Heistek TS, Real JI, Xavier C, Cunha RA, Mansvelder HD and Ferreira SG (2018)  Adenosine A2A Receptors Control Glutamatergic Synaptic Plasticity in Fast Spiking Interneurons of the Prefrontal Cortex.  Front. Pharmacol., 20 March 2018, doi.org/10.3389/fphar.2018.00133.

263.  Kim S, Yu NK, Shim KW, Kim J, Kim H, Han DH, Choi JE, Lee S-W, Choi DI, Kim MW, Lee D-S, Lee K, Galjart N, Lee Y-S, Lee J-H and Kaang B-K  (2018)  Remote memory and cortical synaptic plasticity require neuronal CCCTC-binding factor (CTCF).  J. Neuroscience, 38:5042–5052.

262.  Lepannetier S, Gualdani R, Tempesta S, Schakman 0, Seghers F, Kreis A, Yerna X, Slimi A, de Clippele M, Tajeddine N, Voets T, Bon RS, Beech DJ, Tissir F and Gailly P  (2018)  Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory. Front.  Cell. Neurosci., 12:318; doi: 10.3389/fncel.2018.00318.

261. Manz KM, Levine WA, Seckler JC, Iskander AN and Reich CG  (2018)  A novel adolescent chronic social defeat model: reverse-Resident-Intruder Paradigm (rRIP) in male rats.  International Journal on the Biology of Stress, 21:169-178, doi.org/10.1080/10253890.2017.1423285.

260.  Martinez-Losa M, Tracy TE, Ma K, Verret L, Clemente-Perez A, Khan AS, Cobos I, Ho K, Gan L, Mucke L, Alvarez-Dolado M and Palop JJ  (2018)  Neuron, in press; doi.org/10.1016/j.neuron.2018.02.029.

259.  McGregor G, Clements L, Farah A, Irving AJ and Harvey J  (2018)  Age-dependent regulation of excitatory synaptic transmission at hippocampal temporoammonic-CA1 synapses by leptin.  Neurobiology of Aging, 69:76-93.

258.  Michaelides M, Miller ML, Egervari G, Primeaux SD, Gomez JL, Ellis RJ, Landry JA, Szutorisz H, Hoffman AF, Lupica CR, Loos RJF, Thanos PK, Bray GA, Neumaier JF, Zachariou V, Wang G-J, Volkow ND and Hurd YL  (2018) Striatal Rgs4 regulates feeding and susceptibility to diet-induced obesity.  Mol Psychiatry, doi: 10.1038/s41380-018-0120-7.

257. Mlinar B and Corradetti R  (2018)  Differential modulation of CA1 impulse flow by endogenous serotonin along the hippocampal longitudinal axis.  Hippocampus, doi.org/10.1002/hipo.22825

256.   Morató X, Gonçalves FQ, Lopes JP, Jauregui O, Soler C, Fernández‐Dueñas V, Cunha RA and Ciruela F  (2018) Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD in GPR37 deficient mice.  J. Neurochem., doi.org/10.1111/jnc.14653.

255.  Morel C, Sherrin T, Kennedy NJ, Forest KH, Barutcu SA, Robles M, Carpenter-Hyland E, Alfulaij N, Standen CL, Nichols RA, Benveniste M, Davis RJ and Todorovic C  (2018)  JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory. Journal of Neuroscience, 14 March 2018, 1913-17; doi.org/10.1523/JNEUROSCI.1913-17.2018.

254. Muzzi M, Gerace E, Buonvicino D, Coppi E, Francesco Resta 2, Formentini L, Zecchi R, Tigli L, Guasti D, Ferri M, Camaioni E, Masi A, Pellegrini-Giampietro DE, Mannaioni G, Bani D, Pugliese AM and Chiarugi A (2018) 

253.  Park HJ, Kang H, Jo J, Chung E and Kim S  (2018)  Planar coil-based contact-mode magnetic stimulation: synaptic responses in hippocampal slices and thermal considerations.  Scientific Rreports, 8, Article number: 13423.

252.  Purkey AM, Woolfrey KM, Crosby KC, Stich DG, Chick WS, Aoto J and Dell’Acqua ML  (2018)  AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca2+-Permeable AMPA Receptors to Control LTP.  Cell Reports, 25:P74-987.e4; doi.org/10.1016/j.celrep.2018.09.085.

251.  Rajgor D, Sanderson TM, Amici M, Collingridge GL and Hanley JG  (2018)  NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity.  The EMBO Journal, 37:e97943|2018.

250.  Real JI, Simões AP, Cunha RA, Ferreira SG and Rial D  (2018)  Adenosine A2A receptors modulate the dopamine D2 receptor-mediated inhibition of synaptic transmission in the mouse prefrontal cortex. Eur. J. Neuroscience, 47:1127–1134.

249.  Sabec MH, Wonnacott S, Warburton EC and Bashir ZI  (2018)  Nicotinic Acetylcholine Receptors Control Encoding and Retrieval of Associative Recognition Memory through Plasticity in the Medial Prefrontal Cortex.  Cell Reports, 22:3409-3415.

248. Samidurai M, Ramasamy VS and Jo J (2018) ß-amyloid inhibits hippocampal LTP through TNFR/IKK/NF-?B pathway. Neurological Research, 40:268-276, doi.org/10.1080/01616412.2018.1436872.

247.  Sanderson TM, Bradley CA, Georgiou J, Hong YH, NaNg A, Lee Y, Kim H-D, Kim D, Amici M, Son GH, Zhuo M, Kim K, Kaang B-K, Kim SJ and Collingridge GL  (2018)  The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface Expression.  Cell Reports, 25:3631-3646.e3.

246.  Silva AC, Lemos C, Gonçalves FQ, Pliássova AV, Machadoa NJ, Silvaa HB, Canas PM, Cunha RA, Lopes JP and Agostinho P  (2018)  Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease.  Neurobiology of Disease, 117:72-81.

245.  Tapia-Rojas C, Carvajal FJ, Mira RG, Arce C, Lerma-Cabrera JM, Orellan JA, Cerpa W and Quintanilla RA  (2018)  Adolescent binge alcohol exposure affects the brain function through mitochondrial impairment.  Mol. Neurobiol. 55:4473-4491; doi.org/10.1007/s12035-017-0613-4.

244.  Wenzel JM, Oleson EB, Gove WN, Cole AB, Gyawali U, Dantrassy HM, Bluett RJ, Dryanovski DI, Stuber GD, Deisseroth K, Mathur BN, Patel S. Lupica CR and Cheer JF  (2018)  Phasic Dopamine Signals in the Nucleus Accumbens that Cause Active Avoidance Require Endocannabinoid Mobilization in the Midbrain.  Current Biology, 28:1392-1404.e5.

243. Zhou Z, Liu A, Xia S, Leung C, Qi J, Meng Y, Xie W, Park P, Collingridge GL and Jia Z  (2018)  The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning.  Nature Neuroscience, 21:50–62, doi:10.1038/s41593-017-0030-z.

 

 

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242.  Ahuja M, Buabeid M, Abdel-Rahman E, Majrashi M, Parameshwaran K, Amin R, Ramesh S, Thiruchelvan K, Pondugula S, Suppiramaniam V and Dhanasekaran M  (2017)  Life Sciences, 177:49-59, doi.org/10.1016/j.lfs.2017.03.004.

241.  Antila H, Ryazantseva MA, Popova D, Sipilä P, Guirado R, Kohtala S, Yalçin I, Lindholm J, Vesa L, Sato VT, Cordeira JW, Autio H, Kislin M, Ríos MP, Joca SRL, Casarotto PC, Khiroug LS, Lauri SE, Taira T, Castrén E and Rantamäki T (2017)  Isoflurane produces antidepressant effects and induces TrkB signaling in rodents.  Scientific Reports, DOI: 10.1038/s41598-017-08166-9.

240.  Audrain M, Souchet B, Alves S, Fol R, Viode A, Haddjeri A, Tada S, Orefice NS, Joséphine C, Bemelmans A-P, Delzescaux T, Déglon N, Hantraye P, Akwa Y, Becher F, Billard J-M, Potier B, Dutar P, Cartier N and Braudeau J  (2017)ßAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease.  Cerebral Cortex, doi.org/10.1093/cercor/bhx260.

239.  Badri O, Shahabi P, Abdolalizadeh J, Alipour MR, Veladi H, Farhoudi M and Zak MS  (2017)  Combination therapy using evening primrose oil and electrical stimulation to improve nerve function following a crush injury of sciatic nerve in male rats.  Neural Regen. Res., 12:458–463, doi:10.4103/1673-5374.202927.

238.  Daumas S, Hunter CJ, Mistry RB, Morè L, Privitera L, Cooper DD, Reyskens KM, Flynn HT, Morris RGM, Arthur JSC and Frenguelli BG  (2017)  The Kinase Function of MSK1 Regulates BDNF Signaling to CREB and Basal Synaptic Transmission, But Is Not Required for Hippocampal Long-Term Potentiation or Spatial Memory.  eNeuro, 4:ENEURO.0212-16.2017, DOI: https://doi.org/10.1523/ENEURO.0212-16.2017.

237.  Ferreira DG, Temido-Ferreira M, Miranda HV, Batalha VL, Coelho JE, Szegö EM, Marques-Morgado I, Vaz SH, Rhee JS, Schmitz M, Zerr I, Lopes LV and Outeiro TF  (2017)  a-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B.  Nature Neuroscience, 20:1569–1579, doi:10.1038/nn.4648.

236.  France G, Fernández-Fernández D, Burnell ES, Irvine MW, Monaghan DT, Jane DE, Bortolotto ZA, Collingridge GL and Volianskis A  (2017)  Neuropharmacology, 112:76-83, doi.org/10.1016/j.neuropharm.2016.08.010.

235.  He J, Guo R, Qiu P, Su X, Yan G and Feng J  (2017)  Exogenous hydrogen sulfide eliminates spatial memory retrieval impairment and hippocampal CA1 LTD enhancement caused by acute stress via promoting glutamate uptake.  Neuroscience, 350:110-123, doi.org/10.1016/j.neuroscience.2017.03.018. 

234.  Hoffman AF, Lycas MD, Kaczmarzyk JR, Spivak CE, Baumann MH and Lupica CR  (2017)  Disruption of hippocampal synaptic transmission and long-term potentiation by psychoactive synthetic cannabinoid ‘Spice’ compounds: comparison with ?9-tetrahydrocannabinol.  Addiction Biology, 22:390-399, doi.org/10.1111/adb.12334.

233.  Hsieh C, Tsokas P, Serrano P, Hernández AI, Tian D, Cottrell JE, Shouval HZ, Fenton AA, and Sacktor TC  (2017)Persistent increased PKM? in long-term and remote spatial memory. Neurobiol Learn Mem., 138:135–144. doi:10.1016/j.nlm.2016.07.008.

232.  Huang Yana, Shen W, Su J, Cheng B, Li D, Liu G, Zhou W-X and Zhang Y-X  (2017)  Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-ß-Induced Neurotoxicity.  J. Alzheimer's Disease, 57:885-897, DOI: 10.3233/JAD-161186.

231.  Hwang K-D, Bak MS, Kim SJ, Rhee S and Lee Y-S  (2017)  Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition.  Molecular Brain, 10:57, DOI 10.1186/s13041-017-0338-3.

230.  Kang H, Park P, Bortolotto ZA, Brandt SD, Colestock T, Wallach J, Collingridge GL and Lodge D  (2018)  Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties.  Neuropharmacology, 112:144-149, doi.org/10.1016/j.neuropharm.2016.08.004.

229.  Lim C-S, Nam HJ, Lee J, Kim D, Choi JE, Kang SJ, Kim S, Kim H, Kwak C, Shim K-W, Kim S, Ko H-G, Lee RU, Jang EH, Yoo J, Shim J, Islam MA, Lee Y-S, Lee J-H, Baek SH and Kaang B-K  (2017)  PKCa-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory.  Scientific Reports, vol 7, Article number:4912, doi:10.1038/s41598-017-05239-7.

228.  Luchkina NV, Coleman SK, Huupponen J, Cai C, Kivistö1 A, Taira T, Keinänen K and Lauri SE  (2017)  Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPAreceptors critical for functional maturation of CA1 glutamatergic synapses.  Neuropharmacology, 112:46-56, doi.org/10.1016/j.neuropharm.2016.04.049.

227.  Machado NJ, Simões AP, Silva HB, Ardais AP, Kaster MP, Garção P, Rodrigues DI, Pochmann D, Santos AI, Araújo IM, Porciúncula LO, Tomé AR, Köfalvi A, Vaugeois J-M, Agostinho P, El Yacoubi M, Cunha RA and Gomes CA  (2017)  Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses.  Molecular Neurobiology, 54:1552–1563, doi.org/10.1007/s12035-016-9774-9.

226.  McGregor G, Irving AJ and Harvey H  (2017)  Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses.  The FASEB Journal, 31:3449-3466, doi.org/10.1096/fj.201601293RR.

225.  Miranda HV, Szego EM, Oliveira LMA, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A and Outeiro TF  (2017)  Glycation potentiates a-synuclein-associated neurodegeneration in synucleinopathies.  Brain, 140:1399–1419, doi.org/10.1093/brain/awx056.

224. Muzzia M, Buonvicino D, De Cesaris F and Chiarugi A  (2017)  Acute and chronic triptan exposure neither alters rodent cerebral blood flow nor worsens ischemic brain injury. Neuroscience, 340:1-7, doi.org/10.1016/j.neuroscience.2016.10.046.

223.  Oliveira DR, Luchez CV, Bortolotto ZA and Fernandes JPS  (2017)  Evaluation of ß-Aminocarboxylic Acid Derivatives in Hippocampal Excitatory Synaptic Transmission.  Arch. Pharm., 350:170-179, doi.org/10.1002/ardp.201700179.

222.  Orav E, Atanasova T, Shintyapina A, Kesaf S, Kokko M, Partanen J, Taira T and Lauri SE  (2017)  NETO1 Guides Development of Glutamatergic Connectivity in the Hippocampus by Regulating Axonal Kainate Receptors.  eNeuro, 4:ENEURO.0048-17.2017, DOI: https://doi.org/10.1523/ENEURO.0048-17.2017.

221.  Paci P, Gabriele S and Ris L  (2017)  A new method allowing long-term potentiation recordings in hippocampal organotypic slices.  Brain and Behavior, DOI: 10.1002/brb3.692.

220.  Park HJ, Kang HK, Wang M, Jo J, Chung E and Kim S  (2017)  A pilot study of planar coil based magnetic stimulation using acute hippocampal slice in mice.  Engineering in Medicine and Biology Society (EMBC), 2017 39th Annual International Conference of the IEEE, DOI: 10.1109/EMBC.2017.8037025.

219.  Pinho J, Vale R, Batalha VL, Costenla AR, Dias R, Rombo D, Sebastião AM, Mendonça A and Diógenes MJ  (2017)Enhanced LTP in aged rats: Detrimental or compensatory? Neuropharmacology, 114:12-19, doi.org/10.1016/j.neuropharm.2016.11.017.

218.  Popova D, Castrén E and Tair T  (2018)  Chronic fluoxetine administration enhances synaptic plasticity and increases functional dynamics in hippocampal CA3-CA1 synapses. Neuropharmacology, 126:250-256, doi.org/10.1016/j.neuropharm.2017.09.003.

217.  Rammes G, Mattusch C, Wulff M, Seeser F, Kreuzer M, Zhud K, Deussing JM, Herms J and Parsons CG  (2017)Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aß) in murine models of Alzheimer's disease (AD).  Neuropharmacology, 123:100-115, doi.org/10.1016/j.neuropharm.2017.02.003.

216. Rial D, Morató X, Real JI, Gonçalves FQ, Stagljard I, Pereira FC, Fernández-Dueñas V, Cunha RA and Ciruela F (2017)  Parkinson’s disease-associated GPR37 receptor regulates cocaine-mediated synaptic depression in corticostriatal synapses.  Neuroscience Letters, 638:162-166, doi.org/10.1016/j.neulet.2016.12.040.

215.  Sason H, Billard JM, Smith GP, Safory H, Neame S, Kaplan E, Rosenberg D, Zubedat S, Foltyn VN, Christoffersen CT, Bundgaard C, Thomsen C, Avital A, Christensen KV and Wolosker H  (2018)  Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of d-Serine in the Forebrain.  Cerebral Cortex, 27:1573–1587, doi.org/10.1093/cercor/bhv350.

214.  Seo BA, Cho T, Lee DZ, Lee HY, Lee J-J, Lee B, Kim S-W, Cunningham KA, Dineley KT, Green TA, Kim HM, Choi S-Y, Shin H-S and Kang M-G  (2017)  LARGE, an AMPA receptor interactor, plays a large role in long-term memory formation by driving homeostatic scaling-down.  Cold Spring Harbor Laboratory, bioRxiv, doi.org/10.1101/236547.

213.  Silva-Cruz A, Carlström M, Ribeiro JA and Sebastião AM  (2017)  Dual Influence of Endocannabinoids on Long-Term Potentiation of Synaptic Transmission.  Front. Pharmacol., doi.org/10.3389/fphar.2017.00921.

212.  Sinnen BL, Bowen AB, Forte JS, Hiester BG, Crosby KC, Gibson ES, Dell’Acqua ML and Kennedy MJ  (2017)Optogenetic Control of Synaptic Composition and Function.  Neuron, 93:646-660, doi.org/10.1016/j.neuron.2016.12.037.

211.  Socodato R, Portugal CC, Canedo T, Henriques J, Vaz SH, Magalhaes JD, Silva CM, Baptista FI, Alves RL, Nogueira J, Coelho-Santos V, Silva AP, Paes-de-Carvalho R, Magalhaes A, Summavielle T, Brakebusch C, Sebastiao AM, Ambrosio AF and Relvas JB  (2017)  Genetic ablation of RhoA in adult microglia causes synapse and neuronal loss.  Cold Spring Harbor Laboratory, bioRxiv, doi.org/10.1101/218107.

210.  Tapia-Rojas C, Carvajal FJ, Mira RG, Arce C, Lerma-Cabrera JM, Orellana JA, Cerpa W and Quintanilla RA  (2017)Adolescent Binge Alcohol Exposure Affects the Brain Function Through Mitochondrial Impairment.  Mol. Neurobiol., doi.org/10.1007/s12035-017-0613-4.

209.  Tidball P, Burn HV, Teh KL, Volianskis A, Collingridge GL and Fitzjohn SM  (2017)  Differential ability of the dorsal and ventral rat hippocampus to exhibit group I metabotropic glutamate receptor–dependent synaptic and intrinsic plasticity.  Brain and Neuroscience Advances, 1:1–13, DOI: 10.1177/2398212816689792.

208.  Yu YH, Lee K, Sin DS, Park K-H, Park D-K and Kim DS  (2017)  Altered functional efficacy of hippocampal interneuron during epileptogenesis following febrile seizures.  Brain Research Bulletin, 131:25-38, doi.org/10.1016/j.brainresbull.2017.02.009.

207.  Wang C, Ward ME, Chen R, Liu K, Tracy TE, Chen X, Xie M, Sohn PD, Ludwig C, Meyer-Franke A, Karch CM, Ding S and Gan L  (2017)  Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening.  Stem Cell Reports, http://dx.doi.org/10.1016/j.stemcr.2017.08.019.

206.  Witkin JM, Ornstein PL, Mitch CH, Li R, Smith SC, Heinz BA, Wang X-S, Xiang C, Carter JH, Anderson WH, Li X, Broad LM, Pasqui F, Fitzjohn SM, Sanger HE, Smith JL, Catlow J, Swanson S, Monn JA  (2017)  In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu2/3 receptor antagonist.  Neuropharmacology, 115:100-114, doi.org/10.1016/j.neuropharm.2015.12.021.

205.  Zapata A, Hwang E-K and Lupica CR  (2018)  Lateral Habenula Involvement in Impulsive Cocaine Seeking.  Neuropsychopharmacology, 42:1103–1112, doi:10.1038/npp.2016.286.

 

 

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204.  Abrahamsson T, Lalanne T, Watt AJ and Sjöström PJ  (2016)  Long-Term Potentiation by Theta-Burst Stimulation using Extracellular Field Potential Recordings in Acute Hippocampal Slices.  Cold Spring Harb Protoc. 2016(6):pdb.prot091298; doi:10.1101/pdb.prot091298.

203.  Antila H, Casarotto P, Popova D, Sipila P, Guirado R, Kohtala S, Ryazantseva M, Vesa L, Lindholm J, Yalcin I, Sato V, Goos H, Lempriere S, Cordeira J, Autio H, Kislin M, Rios M, Joca S, Khiroug L, Lauri S, Varjosalo M, Grant SGN, Taira T, Castren E and Rantamaki T  (2016)  TrkB signaling underlies the rapid antidepressant effects of isoflurane.  Scientific Reports, doi:10.1038/s41598-017-08166-9 and doi.org/10.1101/084525.

202.  Audrain M, Fol R, Dutar P, Potier B, Billard J-M, Flament J, Alves S, Burlot MA, Dufayet-Chaffaud G, Bemelmans A-P, Valette J, Hantraye P, Déglon N, Cartier N and Braudeau J  (2016)  Alzheimer’s disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.  Molecular Neurodegeneration, 2016 1611:5; doi.org/10.1186/s13024-016-0070-y.

201.  Barbieri M, Ossato A, Canazza I, Trapella C, Borelli AC, Beggiato S, Rimondo C, erpelloni G, Ferraro L and Marti M (2016)  Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence.  Neuropharmacology, 109:254-269; doi.org/10.1016/j.neuropharm.2016.06.027.

200.  Barcomb K, Hell JW, Benke TA and Bayer KU  (2016)  The CaMKII/GluN2B Protein Interaction Maintains Synaptic Strength.  J. Biol. Chem., 291:16082–16089; DOI 10.1074/jbc.M116.734822.

199.  Bertling E, Englund J, Minkeviciene R, Koskinen M, Segerstråle M, Castrén E, Taira T and Hotulainen P  (2016)  Actin Tyrosine-53-Phosphorylation in Neuronal Maturation and Synaptic Plasticity.  Journal of Neuroscience, 36:5299-5313; doi.org/10.1523/JNEUROSCI.2649-15.2016.

198.  Chiodi V, Ferrante A, Ferraro L, Potenza RL, Armida M, Beggiato S, Pèzzola A, Bader M, Fuxe K, Popoli P and Domenici RM  (2016)  Striatal adenosine–cannabinoid receptor interactions in rats over-expressing adenosine A2A receptors.  J. Neurochem. 136:07-917; doi.org/10.1111/jnc.13421.

197.  Colino-Oliveira M, Rombo DM, Dias RB, Ribeiro JA and Sebastião AM  (2016)  BDNF-induced presynaptic facilitation of GABAergic transmission in the hippocampus of young adults is dependent of TrkB and adenosine A2A receptors. Purinergic Signalling, DOI 10.1007/s11302-016-9502-y.

196.  Fitzjohn S, Bashir Z and Farrow P  (2016)  Group I mGluR Induced LTD of NMDAR-synaptic Transmission at the Schaffer Collateral but not Temperoammonic Input to CA1.  Curr. Neuropharmacol., 14:435–440; doi:10.2174/1570159X13666150615221502.

195.  Ghaffarian N, Mesgari M, Cerina M, Göbel K, Budde T, Speckmann E-J and Meuth SG  (2016)  Thalamocortical-auditory network alterations following cuprizone-induced demyelination.  Journal of Neuroinflammation, 13:160; doi.org/10.1186/s12974-016-0629-0.

194.  Goodell DJ, Benke TA and Bayer KU  (2016)  Developmental restoration of LTP deficits in heterozygous CaMKIIa KO mice.  J. Neurophysiol., 116:2140-2151; doi.org/10.1152/jn.00518.2016.

193.  Hoffmann HM, Crouzin N, Moreno E, Raivio N, Fuentes S, McCormick PJ, Ortiz J, Vignes M  (2016)  Long-Lasting Impairment of mGluR5-Activated Intracellular Pathways in the Striatum After Withdrawal of Cocaine Self-Administration. International Journal of Neuropsychopharmacology, 20:72–82, doi.org/10.1093/ijnp/pyw086.

192.  Huh S, Baek S-J, Lee K-H, Whitcomb DJ, Jo J, Choi S-M, Kim DH, Park M-S, Lee KH and Kim BC  (2016)  The reemergence of long-term potentiation in aged Alzheimer’s disease mouse model.  Scientific Reports, 6:29152; doi:10.1038/srep29152.

191.  Hunsberger HC, Wang D, Petrisko TJ, Alhowail A, Setti SE, Suppiramaniam V, Konat GW and Reed MN  (2016)  Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus.  J. Neurochem., 138:307–316; doi:10.1111/jnc.13665.

190.  Kailainathan S, Piers TN, Yi JH, Choi S, Fahey MS, Borger E, Gunn-Moore FJ, O’Neill L, Lever M, Whitcomb DJ, Cho K and Allen SJ  (2016)  Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF).  Pharmacological Research, 104:97-107; doi.org/10.1016/j.phrs.2015.12.008.

189.  Kerr DJ, Marsillo A, Guariglia SR, Budylin T, Sadek R, Menkes S, Chauhan A, Wen GY, McCloskey DP, Wieraszko A and Banerjee P  (2016)  Aberrant hippocampal Atp8a1 levels are associated with altered synaptic strength, electrical activity, and autistic-like behavior.  Biochimica et Biophysica Acta - Molecular Basis of Disease, 1862:1755-1765; doi.org/10.1016/j.bbadis.2016.06.005.

188.  Kim S, Kim T, Lee H-R, Jang E-H, Ryu H-H, Kang M, Rah S-Y, Yoo J, Lee B, Kim J-I, Lim CS, Kim SJ, Kim U-H, Lee Y-S and Kaang B-K  (2016)  Impaired learning and memory in CD38 null mutant mice.  Molecular Brain, 9:16; doi.org/10.1186/s13041-016-0195-5.

187.  Lantoine J, Grevesse T, Villers A, Delhaye G, Mestdagh C, Versaevel M, Mohammed D, Bruyère C, Alaimo L, Lacour SP, Ris L and Gabriele S  (2016)  Matrix stiffness modulates formation and activity of neuronal networks of controlled architectures.  Biomaterials, 89:14-24; doi.org/10.1016/j.biomaterials.2016.02.041.

186.  Li D, Huang Y, Cheng B, Su J, Zhou W-X and Zhang Y-X  (2016)  Streptozotocin Induces Mild Cognitive Impairment at Appropriate Doses in Mice as Determined by Long-Term Potentiation and the Morris Water Maze.  Journal of Alzheimer's Disease, 54:89-98, DOI: 10.3233/JAD-150979.

185.  Lipina TV, Prasad T, Yokomaku D, Luo L, Connor SA, Kawabe H, Wang YT, Brose N, Roder JC and Craig AM  (2016)  Cognitive Deficits in Calsyntenin-2-deficient Mice Associated with Reduced GABAergic Transmission.  Neuropsychopharmacology, 41:802–810; doi:10.1038/npp.2015.206.

184.  Logue OC, Cramer NP, Xu X, Perl DP and Galdzicki Z  (2016)  Alterations of functional properties of hippocampal networks following repetitive closed-head injury. Experimental Neurology, 277:227-243; doi.org/10.1016/j.expneurol.2015.12.019.

183.  Lopes S, Vaz-Silva J, Pinto V, Dalla C, Kokras N, Bedenk B, Mack N, Czisch M, Almeida OFX, Sousa N and Sotiropoulos I  (2016)  Tau protein is essential for stress-induced brain pathology.  PNAS, 113:E3755-E3763; doi.org/10.1073/pnas.1600953113.

182.  Maeda S, Djukic B, Taneja P, Yu G-Q, Lo I, Davis A, Craft R, Guo W, Wang X, Kim D, Ponnusamy R, Gill TM, Masliah E and Mucke L  (2016)  Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.  EMBO Reports, 17:530-551, DOI 10.15252/embr.201541438.

181.  Malekizadeh Y, Holiday A, Redfearn D, Ainge JA, Doherty G and Harvey J  (2016)  A Leptin Fragment Mirrors the Cognitive Enhancing and Neuroprotective Actions of Leptin.  Cerebral Cortex, 27:4769–4782; doi.org/10.1093/cercor/bhw272.

180.  Molchanova SM, Huupponen J, Lauri SE and Taira T  (2016)  Gap junctions between CA3 pyramidal cells contribute to network synchronization in neonatal hippocampus.  Neuropharmacology, 107:9-17, doi.org/10.1016/j.neuropharm.2016.02.033.

179.  O'Leary H, Bernard PB, Castano AM and Benke TA  (2016)  Enhanced long term potentiation and decreased AMPA receptor desensitization in the acute period following a single kainate induced early life seizure.  Neurobiology of Disease, 87:134-144; doi.org/10.1016/j.nbd.2015.12.005.

178.  O’Toole SM, Ferrer MM, Mekonnen J, Zhang H, Shima Y, Ladle DR and Nelson SB  (2018)  Dicer maintains the identity and function of proprioceptive sensory neurons.  J. Neurophysiology, 117:1057-1069, doi.org/10.1152/jn.00763.2016.

177.  Park P, Sanderson TM, Amici M, Choi S-L, Bortolotto ZA, Zhuo M, Kaang B-K and Collingridge GL  (2016)  Calcium-Permeable AMPA Receptors Mediate the Induction of the Protein Kinase A-Dependent Component of Long-Term Potentiation in the Hippocampus.  Journal of Neuroscience, 36:622-631; doi.org/10.1523/JNEUROSCI.3625-15.2016.

176.  Picot M, Billard J-M, Dombret C, Albac C, Karameh N, Daumas S, Hardin-Pouzet H and Mhaouty-Kodja S  (2016)  Neural Androgen Receptor Deletion Impairs the Temporal Processing of Objects and Hippocampal CA1-Dependent Mechanisms.  PLOS, doi.org/10.1371/journal.pone.0148328.

175.  Saffarzadeh F, Eslamizade MJ, Mousavi SMM, Abraki SB, Hadjighassem MR and Gorji A  (2016)  TRPV1 receptors augment basal synaptic transmission in CA1 and CA3 pyramidal neurons in epilepsy.  Neuroscience, 314:170-178; doi.org/10.1016/j.neuroscience.2015.11.045.

174.  Sandau US, Colino-Oliveira M, Jones A, Saleumvong B, Coffman SQ, Liu L, Miranda-Lourenco C, Palminha C, Batalha VL, Xu Y, Huo Y, Diogenes MJ, Sebastiao AM and Boison D  (2017)  Adenosine Kinase Deficiency in the Brain Results in Maladaptive Synaptic Plasticity.  J. Neuroscience, 36:12117–12128.

173.  Sengupta T, Das R and Chattarji S  (2016)  Chronic but not acute immobilization stress stably enhances hippocampal CA1 metabotropic glutamate receptor dependent Long-Term Depression.  Neuroscience Letters, 633:101-105; doi.org/10.1016/j.neulet.2016.09.031.

172.  Sinnen BL, Bowen AB, Gibson ES and Kennedy MJ  (2018)  Local and Use-Dependent Effects of ß-Amyloid Oligomers on NMDA Receptor Function Revealed by Optical Quantal Analysis.  J Neurosci., 36:11532–11543, doi:10.1523/JNEUROSCI.1603-16.2016.

171.  Tsokas P, Hsieh C, Yao Y, Lesburguères E, Wallace EJC, Tcherepanov A, Jothianandan D, Hartley BR, Pan L, Rivard B, Farese RV, Sajan MP, Bergold PJ, Hernández AI, Cottrell JE, Shouval HZ, Fenton AA and Sacktor TC  (2016)Compensation for PKM? in long-term potentiation and spatial long-term memory in mutant mice.  eLife. 2016; 5: e14846; doi: 10.7554/eLife.14846.

170.  Vingtdeux V, Chang EH, Frattini SA, Zhao H, Chandakkar P, Adrien L, Strohl JJ, Gibson EL, Ohmoto M, Matsumoto I, Huerta PT and Marambaud P  (2016)  CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice.  Scientific Reports, 6:2425O; doi:10.1038/srep24250.

169.  Wallach J, Kang H, Colestock T, Morris H, Bortolotto ZA, Collingridge GL, Lodge D, Halberstadt AL, Brandt SD and Adejare A  (2016)  Pharmacological Investigations of the Dissociative ‘Legal Highs’ Diphenidine, Methoxphenidine and Analogues.  PLOS, doi.org/10.1371/journal.pone.0157021.

168.  Wright AM, Zapata A, Baumann MH, Elmore JS, Hoffman AF and Lupica CR  (2016)  Enduring Loss of Serotonergic Control of Orbitofrontal Cortex Function Following Contingent and Noncontingent Cocaine Exposure.  Cerebral Cortex, 27:5463–5476; doi.org/10.1093/cercor/bhw312.

 

 

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167.  Banks PB, Burroughs AC, Barker GRI, Brown JT, Warburton EC and Bashir ZI  (2015)  Disruption of hippocampal–prefrontal cortex activity by dopamine D2R-dependent LTD of NMDAR transmissiON.  Proc. Nat. Acad. Sci., 112:11096–11101; doi/10.1073/pnas.1512064112.

166.  Barnes SA, Pinto-Duarte A, Kappe A, Zembrzycki A, Metzler A, Mukamel EA, Lucero J, Wang X, Sejnowski TJ, Markou A and Behrens MM  (2015)  Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders.  Molecular Psychiatry, 20:1161–1172; doi:10.1038/mp.2015.113.

165.  Barnes SA, Wijetunge LS, Jackson AD, Katsanevaki D, Osterweil EK, Komiyama NH, Grant SGN, Bear MF, Nägerl UV, Kind PC and Wyllie DJA  (2015)  Convergence of Hippocampal Pathophysiology in Syngap+/- and Fmr1-/y Mice.  Jounal of Neuroscience, 35:15073-15081; DOI: dx.doi.org/10.1523/JNEUROSCI.1087-15.2015.

164.  Buscetia CL, Di Pietroa P, Riozzia B, Traficantea A, Biagionia F, Nisticò R, Fornai F, Battaglia G, Nicoletti F and Bruno V (2015)  5-HT2C serotonin receptor blockade prevents tau protein hyperphosphorylation and corrects the defect in hippocampal synaptic plasticity caused by a combination of environmental stressors in mice. Pharmacological Research, 99:258–268.

163.  De Filippis B, Chiodi V, Adriani W, Lacivita E, Mallozzi C, Leopoldo M, Domenici MR, Fuso A and Laviola G (2015) Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome. Front. Behav. Neurosci., 9:86, doi: 10.3389/fnbeh.2015.0008.

162.  De Filippisa B, Valenti D, Chiodi V, Ferrante A, de Bari L, Fiorentini C, Domenici MR, Ricceri L, Vacca RA, Fabbri A and Laviola G  (2015)  Modulation of Rho GTPases rescues brain mitochondrial dysfunction, cognitive deficits and aberrant synaptic plasticity in female mice modeling Rett syndrome. European Neuropsychopharmacology, 25:889–90

161.  Dubal DB, Zhu L, Sanchez PE, Worden1 K, Broest L, Johnson E, Ho K, Yu G-Q, Kim D, Betourne A, Kuro-o M, Masliah E, Abraham CR and Mucke L (2015) Life extension factor Klotho prevents mortality and enhances cognition in hAPP transgenic mice. J. Neurosci., 35:2358-2371; doi: 10.1523/JNEUROSCI.5791-12.2015.

160.  Jiang Z-J, Wang C-Y, Xie X, Yang J-F, Huang J-N, Cao Z-P, Xiao P and Li C-H (2015) Schizandrin ameliorates ovariectomy-induced memory impairment, potentiates neurotransmission and exhibits antioxidant properties. British J. Pharmacol., 172:2479–2492, DOI: 10.1111/bph.13078.

159.  Kang M, Ryu H-H and Lee Y-S (2015) Comparisons of behavior and synaptic plasticity among three C57BL/6 substrains. Animal Cells and Systems, DOI:10.1080/19768354.2015.1023830, pages 181-187.

158.  Kariharan T, Nanayakkara G, Parameshwaran K, Bagasrawala I, Ahuja M, Abdel-Rahman E, Amin AT, Dhanasekaran M, Suppiramaniam V and Amin RH (2015) Central activation of PPAR-gamma ameliorates diabetes induced cognitive dysfunction and improves BDNF expression. Neurobiology of Aging, 36:1451–1461.

157.  Kim S, Kim TH, Lee H-R, Kong Y-Y and Kaang B-K  (2015)  Mind Bomb-2 Regulates Hippocampus-dependent Memory Formation and Synaptic Plasticity.  Korean J Physiol. Pharmacol., 19:515-522, doi.org/10.4196/kjpp.2015.19.6.515.

156.  Laing MD and Bashir ZI  (2015)  Presynaptic NR2A-Containing NMDARs Are Required for LTD between the Amygdala and the Perirhinal Cortex: A Potential Mechanism for the Emotional Modulation of Memory?  eNeuro, DOI: 10.1523/ENEURO.0046-14.2015

155.  Lee K, Kobayashi Y, Seo H, Kwak J-H, Masuda A, Lim C-S, Lee H-R, Kang SJJ, Park P, Sim S-E, Kogo N, Kawasaki H, Kaang B-K and Itohara S (2015) Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility. Molecular Brain, 8:38; DOI 10.1186/s13041-015-0130-1.

154.  Lopes JP, Morato X, Souza C, Pinha C, Machado NJ, Canas PM, Silva HB, Stagljar I, Gandía J, Fernández-Dueñas V, Luján R, Cunha RA and Ciruela F (2015) The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system. J. Neurochem., 134:135–146, DOI: 10.1111/jnc.13109.

153.  Lopatář J, Dale N and Frenguelli BG (2015) Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations.  Neuropharmacology, 93:219–228; doi:10.1016/j.neuropharm.2015.01.014.

152.  Luo X, McGregor G, Irving AJ and Harvey J  (2015)  Leptin Induces a Novel Form of NMDA Receptor-Dependent LTP at Hippocampal Temporoammonic-CA1 Synapses.

151.  Lipina TV, Prasad T, Yokomaku D, Luo L, Connor SA, Kawabe H, Wang YT, Brose N, Roder JC and Craig AM (2015) Cognitive Deficits in Calsyntenin-2-deficient Mice Associated with Reduced GABAergic Transmission. Neuropsychopharmacology, doi: 10.1038/npp.2015.206

150.  Mazzocchi-Jones D (2015) Impaired corticostriatal LTP and depotentiation following iPLA2 inhibition is restored following acute application of DHA.   Brain Res. Bulletin, 111:69–75.

149. Marciniak E, Faivre E, Dutar P, Pires CA, Demeyer D, Caillierez R, Laloux C, Buée L, Blum D, and Humez S  (2015)The Chemokine MIP-1a/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory.  Sci Rep. 5:15862, doi: 10.1038/srep15862.

148.  Moreno L, Rose C, Mohanraj A, Allinquant B, Billard J-M and Dutar P  (2015)  sAßPPa Improves Hippocampal NMDA-Dependent Functional Alterations Linked to Healthy Aging.  Journal of Alzheimer's Disease, 48:927-935.

147.   Nejad GG, Shahabi P, Alipoor MR, Pakdel FG, Asghari M and Alvandi MS  (2015)  Ethosuximide Affects Paired-Pulse Facilitation in Somatosensory Cortex of WAG\Rij Rats as a Model of Absence Seizure.  Adv Pharm Bull., 5:483–489, doi: 10.15171/apb.2015.066.

146.  Nejad GG, Vastyanov RS, Shahabi P, Alipoor MR and Pakdel FG  (2015)  Abnormalities in the GABAergic Inhibitory System Leading to the Development of Spike-Wave Discharges in the Somatosensory Cortex of Wag/Rij Rats.  Neurophysiology, 47:454-458.

145.  Pinto V, Costa JC, Morgado P, Mota C, Miranda A, Bravo FV, Oliveira TG, Cerqueira JJ and Sousa N  (2015)  Differential impact of chronic stress along the hippocampal dorsal–ventral axis. Brain Struct. Funct., DOI 10.1007/s00429-014-0713-0.

144.  Parameshwaran K, Irwin MH, Steliou K, Suppiramaniam V and Pinkert CA  (2015)  Antioxidant-Mediated Reversal of Oxidative Damage in Mouse Modeling of Complex I Inhibition. Drug Development Research, 76:72–81, DOI: 10.1002/ddr.21242.

143.  Regan P, Piers T, Yi J-H, Kim D-H, Huh S, Park SJ, Ryu JH, Whitcomb DJ and Cho K  (2015)  Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD. J. Neurosci., 35:4804-4812; doi: 10.1523/JNEUROSCI.2842-14.2015.

142.  Ribeiro PO, Antunes LM, Nunes CS, Silva HB, Cunha RA and Tome AR (2015) The effects of different concentrations of the α2-adrenoceptor agonist Medetomidine on basal excitatory synaptic transmission and synaptic plasticity in hippocampal slices of adult mice  Anesthesia & Analgesia, 120:1130–1137.

141.  Root DH, Hoffman AF, Good CH, Zhang S, Gigante E, Lupica CR and Morales M (2015) Norepinephrine Activates Dopamine D4 Receptors in the Rat Lateral Habenula.  J. Neurosci., 35:3460-3469; doi: 10.1523/JNEUROSCI.4525-13.2015.

140.  Saffarzadeh F, Eslamizade MJ, Ghadiri T, Mousav SMM, Hadjighassem M and Gorji A  (2015)  Effects of TRPV1 on the hippocampal synaptic plasticity in the epileptic rat brain. Synapse, 69:375–383, DOI: 10.1002/syn.21825.

139.  Shields LY, Kim H, Zhu L, Haddad D, Berthet A, Pathak D, Lam M, Ponnusamy R, Diaz-Ramirez L-G, Gill TM, Sesaki H, Mucke L and Nakamura K (2015) Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons. Cell Death and Disease, 6:e1725; doi:10.1038/cddis.2015.94.

138.  Stancu I-C, Vasconcelos B, Ris L, Wang P, Villers A, Peeraer E, Buist A, Terwel D, Baatsen P, Oyelami T, Pierrot N, Casteels C, Bormans G, Kienlen-Campard P, Octave JN, Moechars D and Dewachter I (2015) Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.  Acta Neuropathologica, 129:875-894.

137.  Suberbielle E, Djukic B, Evans M, Kim DH, Taneja P, Wang X, Finucane M, Knox J, Ho K, Devidze N, Masliah E and Mucke L  (2015)  DNA repair factor BRCA1 depletion occurs in Alzheimer brains and impairs cognitive function in mice.  Nature Communications 6:8897, doi:10.1038/ncomms9897.

136.  Wallis JL, Irvine MW, Jane DE, Lodge D, Collingridge and Bortolotto ZA  (2015)  An interchangeable role for kainate and metabotropic glutamate receptors in the induction of rat hippocampal mossy fiber long-term potentiation in vivo.
Hippocampus, 25:1407–1417, DOI: 10.1002/hipo.22460.

135.  Wang H, Treadway T, Covey DP, Cheer JF and Lupica CR  (2015)  Cocaine-Induced Endocannabinoid Mobilization in the Ventral Tegmental Area.  Cell Reports, 12:1997–2008, doi:10.1016/j.celrep.2015.08.041.

134.  Wei P-J, Yao L-H. Dai D, Huang J-N, Liu W-X, Xiao P and Li C-H (2015) Tenuigenin enhances hippocampal Schaffer collateral-CA1 synaptic transmission through modulating intracellular calcium.  Phytomedicine, 22:807–812.

133.  Whitcomb DJ, Hogg EL, Regan P, Piers T, Narayan P, Whitehead G, Winters BL, Kim D-H, Kim E, St George-Hyslop P, Klenerman D, Collingridge GL, Jo J and Cho K  (2015)  Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus. Scientific Reports, 5:10934; doi:10.1038/srep10934.

 

 

2014   WinLTP

132. Bernard PB, Castano AM, Bayer KU and Benke TA  (2014)  Necessary, but not sufficient: Insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures.  Neuropharmacol., 84:1-12.

131.  Bhouri M, Farrow PA, Motee A, Yan X, Battaglia G, Di Menna L, Riozzi B, Nicoletti F, Fitzjohn SM and Bashir ZI  (2014)  mGlu1 Receptor-Induced LTD of NMDA Receptor Transmission Selectively at Schaffer Collateral-CA1 Synapses Mediates Metaplasticity.  J. Neuroscience, 34(36):12223–12229.

130.  Choi J-H, Park P, Baek GC, Sim SE, Kang SJJ, Lee Y, Ahn S-H, Lim C-S, Lee Y-S, Collingridge GL and Kaang B-K  (2014)  Effects of PI3Kγ overexpression in the hippocampus on synaptic plasticity and spatial learning,  Molecular Brain, 7:78.

129. Chiodi V, Mallozzi C, Ferrante A, Chen JF, Lombroso PJ, Di Stasi AMM, Popoli P and Domenici MR  (2014)  Cocaine-Induced Changes of Synaptic Transmission in the Striatum are Modulated by Adenosine A2A Receptors and Involve the Tyrosine Phosphatase STEP.  Neuropsychopharmacology, 39, 569–578.

128. Clarke VRJ, Molchanova SM, Hirvonen T, Taira T and Lauri SE (2014) Activity-Dependent Upregulation of Presynaptic Kainate Receptors at Immature CA3–CA1 Synapses. J. Neurosci., 34:16902-16916; doi: 10.1523/JNEUROSCI.1842-14.2014.

127.  Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu G-Q, Ho K, Eilertson KE, Yu L, Kuro-o M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL and Mucke L  (2014)  Life Extension Factor Klotho Enhances Cognition.  Cell Reports, 7:1065-1076.

126.  Eom T, Muslimov IA, Tsokas P, Berardi V, Zhong J, Sacktor TC and Tiedge H (2014) Neuronal BC RNAs cooperate with eIF4B to mediate activity-dependent translational control.  J. Cell Biology, 207:237-252; doi: 10.1083/jcb.201401005.

124. Félix-Oliveira A, Dias RB, Colino-Oliveira M, Rombo DM and Sebastião AM  (2014)  Homeostatic plasticity induced by brief activity deprivation enhances long-term potentiation in the mature rat hippocampus. 

123.  Gheyara AL, Ponnusamy R, Djukic B, Craft RJ, Ho K, Guo W, Finucane MM, Sanchez PE and Mucke L  (2014)  Tau Reduction Prevents Disease in a Mouse Model of Dravet Syndrome.  Ann. Neurology, DOI: 10.1002/ana.24230.

122. Jerónimo-Santos A, Batalha VL, Müller CE, Baqi Y, Sebastião AM, Lopes LV and Diógenes MJ  (2014)  Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP.  Neuropharmacology, 83:99-106.

121. Jerónimo-Santos A, Vaz SA, Parreira S, Rapaz-Lérias S, Caetano AP, Buée-Scherrer V, Castrén E, Valente CA, Blum D, Sebastião AM and Diógenes MJ  (2014)  Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain.  Cerebral Cortex, doi:10.1093/cercor/bhu105.

120. Kimura T, Whitcomb DJ, Jo J, Regan P, Piers T, Heo S, Brown C, Hashikawa T, Murayama M, Seok H, Sotiropoulos I, Kim E, Collingridge GL, Takashima A and Cho K  (2014)  Microtubule-associated protein tau is essential for long-term depression in the hippocampus.  Phil. Trans. R. Soc. B, 369:20130144, http://dx.doi.org/10.1098/rstb.2013.0144,

119.  Kumar M, Csaba1 Z, Peineau S, Srivastava1 R, Rasika S, Mani S, Gressens P and El Ghouzzi V (2014) Endogenous cerebellar neurogenesis in adult mice with progressive ataxia. Annals of Clinical and Translational Neurology, 1:968–981; DOI: 10.1002/acn3.137

118.  Lee HS, Ghettia A, Pinto-Duarte A, Wang X, Dziewczapolskia G, Galimi F, Huitron-Resendiz S, Piña-Crespo JC, Roberts AJ, Verma IM, Sejnowski TJ and Heinemann SF  (2014)  Astrocytes contribute to gamma oscillations and recognition memory.  PNAS, www.pnas.org/cgi/doi/10.1073/pnas.1410893111.

116.  Lucantonio F, Takahashi YK, Hoffman AF, Chang CY, Bali-Chaudhary S, Shaham Y, Lupica CR and Schoenbaum G  (2014)  Orbitofrontal activation restores insight lost after cocaine use. Nature Neuroscience, 17:1092-1099, doi:10.1038/nn.3763.

115. Luchkina NV, Huupponen J, Clarke VRJ, Coleman SK, Keinänen K, Taira T and Lauri SE  (2014)  Developmental switch in the kinase dependency of long-term potentiation depends on expression of GluA4 subunit-containing AMPA receptors.  PNAS, 111:4321-4326. 

114. Mango D, Barbato G, Piccirilli S, Panicoa MB, Feligioni M, Schepisi C, Graziani M, Porrini V, Benarese M, Lanzillotta A, Pizzi M, Pieraccini S, Sironi M, Blandini F, Nicoletti F, Mercuri MB, Imbimboi BP and Nisticò R  (2014)  Electrophysiological and metabolic effects of CHF5074 in thehippocampus: Protection against in vitro ischemia.  Pharmacological Research, 81:83–90.

113.  Mondal S, Sengupta T, Pradhan S, Hansda RN, Mandal PS, Tiwari R and Mukhopadhayay SK  (2014)  Impaired learning and memory after a week long exposure of acetamiprid in adult rats. Adv. Anim. Vet. Sci. 2:543-548. DOI | http://dx.doi.org/10.14737/journal.aavs/2014/2.10.543.548

112. Park P, Volianskis A, Sanderson TM, Bortolotto ZA, Jane DE, Zhuo M, Kaang B-K and Collingridge GL  (2014)  NMDA receptor-dependent long-term potentiation comprises a family of temporally overlapping forms of synaptic plasticity that are induced by different patterns of stimulation. Phil. Trans. R. Soc. B, 369:20130131. http://dx.doi.org/10.1098/rstb.2013.0131

110.  Qi J, Zhang S, Wang H-L, Wang H, de Jesus Aceves Buendia J, Hoffman AF, Lupica CR, Seal RP and Morales M (2014) A glutamatergic reward input from the dorsal raphe to ventral tegmental area dopamine neurons. Nature Communications, 5:5390; doi:10.1038/ncomms6390.

109. Ribeiro PO, Tome AR, Silva HB, Cunha RA and Antunes LM  (2014)  Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices.  Brain Res., 1560:10–17.

108. Rodrigues TM, Jerónimo-Santos A, Sebastião AM and Diógenes MJ  (2014)  Adenosine A2A Receptors as novel upstream regulators of BDNFmediated attenuation of hippocampal Long-Term Depression (LTD).  Neuropharmacol., 79:389-398.

107.  Root DH, Mejias-Aponte CA, Zhang S, Wang H-L, Hoffman AF, Lupica CR and Morales M (2014) Single rodent mesohabenular axons release glutamate and GABA. Nature Neuroscience, 17:1543–1551; doi:10.1038/nn.3823.

106. Tong LM, Djukic B, Arnold C, Gillespie AK, Yoon SY, Wang MM, Zhang O, Knoferle J, Rubenstein JLR, Alvarez-Buylla A, and Huang Y  (2014)  Inhibitory Interneuron Progenitor Transplantation Restores Normal Learning and Memory in ApoE4 Knock-In Mice without or with A Accumulation.  J. Neurosci., 34:9506-9515.

  1. 105. Wallach J, Kavanagh PV, McLaughlin G, Morris N, Power JD, Elliott SP, Mercier MS, Lodge D, Morris H, Dempster NM and Brandt SD  (2014)  Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.  Drug Testing and Analysis, DOI: 10.1002/dta.1689.

 

 

2013   WinLTP

104.  Bernard PB, Castano AM, O’Leary H, Simpson K, Browning MD and Benke TA  (2013)  Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.  Neurobiology of Disease, 59:1–17, doi:10.1016/j.nbd.2013.06.013.

103. Cho T, Ryu JK, Taghibiglou C, Ge Y, Chan AW, Liu L, Lu J, McLarnon JG and  Wang YT  (2013)  Long-Term Potentiation Promotes Proliferation/Survival and Neuronal Differentiation of Neural Stem/Progenitor Cells.  PLoS ONE 8(10): e76860. doi:10.1371/journal.pone.0076860.

102. Crabtree JW, Lodge D, Bashir ZI and Isaac JTR (2013)  GABAA, NMDA and mGlu2 receptors tonically regulate inhibition and excitation in the thalamic reticular nucleus.  Eur. J. Neurosci., 37:850–859.

101. Doherty GH, Beccano-Kelly D, Du Yanc S, Gunn-Moorea FJ and Harvey J  (2013)  Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β. Neurobiology of Aging 34:226–237.

100. Felici R, Lapucci A, Ramazzotti M and Chiarugi A  (2013)  Insight into Molecular and Functional Properties of NMNAT3 Reveals New Hints of NAD Homeostasis within Human Mitochondria. PLoS ONE 8(10):e76938, doi:10.1371/journal.pone.0076938

99. Good CH, Wang H, Chen Y-H, Mejias-Aponte CA, Hoffman AF and Lupica CR  (2013)  Dopamine D4 Receptor Excitation of Lateral Habenula Neurons via Multiple Cellular Mechanisms.  J. Neurosci., 33:16853–16864.

98.  González-Sepúlveda M, Rosell S, Hoffmann HM, del Mar Castillo-Ruiz M, Mignon V, Moreno-Delgado D, Vignes M, Díaz J, Sabriá J, Ortiz J  (2013)  Cellular distribution of the histamine H3 receptor in the basal ganglia: Functional modulation of dopamine and glutamate neurotransmission.  Basal Ganglia, 3:109-121.

  • 97. Hanna L, Ceolin L, Lucas S, Monn J, Johnson B, Collingridge G, Bortolotto Z and Lodge D  (2013)  Differentiating the roles of mGlu2 and mGlu3 receptors using LY541850, an mGlu2 agonist/mGlu3 antagonist.  Neuropharmacol., 66:114-121.

96.  Huang Y, Hu Z, Liu G, Zhou W and Zhang Y  (2013)  Cytokines induced by long-term potentiation (LTP) recording: A potential explanation for the lack of correspondence between learning/memory performance and LTP.  Neuroscience, 231:432–443.

95. Latour A, Grintal B, Champeil-Potokar G, Hennebelle M, Lavialle M, Dutar P, Potier B, Billard J-M, Vancassel S, Denis I  (2013)  Omega-3 fatty acids deficiency aggravates glutamatergic synapse and astroglial aging in the rat hippocampal CA1.  Aging Cell, 12:76–84.

94. Lodge D, Tidball P, Mercier MS, Lucas SJ, Hanna L, Ceolin L, Kritikos M, Fitzjohn SM, Sherwood JL, Bannister N, Volianskis A, Jane DE, Bortolotto ZA and Collingridge GL  (2013)  Antagonists reversibly reverse chemical LTD induced by group I, group II and group III metabotropic glutamate receptors.  Neuropharmacol., 74:135–146.

93. Lucas SJ, Bortolotto ZA, Collingridge GL and Lodge D  (2013)  Selective activation of either mGlu2 or mGlu3 receptors can induce LTD in the amygdala. Neuropharmacol., 66:196–201.

92. Luchkina NV, Sallert M, Clarke VRJ, Taira T and Lauri SE  (2013)  Mechanisms underlying induction of LTP-associated changes in short-term dynamics of transmission at immature synapses.  Neuropharmacol., 67:494-502.

91. Martin S, Zekri L, Metz A, Maurice T, Chebli H, Vignes M and Tazi j  (2013)  Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons.  J. Neurochem., 125:175–184.

90. Mercier MS, Lodge D, Fang G, Nicolas CS, Collett VJ, Jane DE, Collingridge GL, Bortolotto ZA  (2013)  Characterisation of an mGlu8 receptor-selective agonist and antagonist in the lateral and medial perforant path inputs to the dentate gyrus. Neuropharmacol., 67:294–303.

89. Panaccione I, King R, Molinaro G, Riozzi B, Battaglia G, Nicoletti F and Bashir ZI  (2013)  Constitutively active group I mGlu receptors and PKMzeta regulate synaptic transmission in developing perirhinal cortex.  Neuropharmacol., 66:143–150.

88. Pettem KL, Yokomaku D, Luo L, Linhoff MW, Prasad T, Connor SA, Siddiqui TJ, Kawabe H, Chen F, Zhang L, Rudenko G, Wang YT, Brose N and Craig AM  (2013)  The Specific a-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development.  Neuron, 80:113–128.

87. Reich CG, Mihalik GR, Iskander AN, Seckler JC AND Weiss MS  (2013)  Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity.  Neuroscience, 253:444-454.

86. Rocca DL, Amici M, Antoniou A, Suarez EB, Halemani N, Murk K, McGarvey J, Jaafari N, Mellor JR, Collingridge GL and Hanley JG  (2013)  The Small GTPase Arf1 Modulates Arp2/3-Mediated Actin Polymerization via PICK1 to Regulate Synaptic Plasticity.  Neuron, 79:293–307.

85. Rosenberg D, Artoul S, Segal AC, Kolodney G, Radzishevsky I, Dikopoltsev E, Foltyn VN, Inoue R, Mori H, Billard J-M, and Wolosker H  (2013)  Neuronal d-serine and glycine release via the Asc-1 transporter regulates NMDA receptor-dependent synaptic activity  J. Neurosci., 33:3533-3544.

84. Scattoni ML, Martire A, Cartocci G, Ferrante A and Ricceri L  (2013)  Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+tf/J strain, a mouse model of autism,  Behavioural Brain Research, dx.doi.org/10.1016/j.bbr.2012.12.028.

83. Siddiqui TJ, Tari PK, Connor SA, Zhang P, Dobie FA, She K, Kawabe H, Wang YT, Brose N and Craig AM  (2013)  An LRRTM4-HSPG Complex Mediates Excitatory Synapse Development on Dentate Gyrus Granule Cells.  Neuron, 79:680–695.

82. Srivastava R, Kumar M, Peineau S, Csaba Z, Mani S, Gressems P and El Ghouzzi V  (2013)  Conditional Induction of Math1 Specifies Embryonic Stem Cells to Cerebellar Granule Neuron Lineage and Promotes Differentiation into Mature Granule Neurons.  Stem Cells, 31:652–665.

81. Sonner PM and Ladle DR  (2013)  Early postnatal development of GABAergic presynaptic inhibition of Ia proprioceptive afferent connections in mouse spinal cord.  J. Neurophysiol. 109:2118-2128.

80. Tamagnini F, Barker GRI, Warburton CE, Burattini C, Aicardi G and Bashir Z  (2013)  Nitric oxide-dependent LTD but not endocannabinoid-LTP is crucial for visual recognition memory. J. Physiol., 591:3963-3979, 10.1113/jphysiol.2013.254862.

79. Titus DJ, Furones C, Kang Y and Atkins CM  (2013)  Age-Dependent Alterations in cAMP Signaling Contribute to Synaptic Plasticity Deficits Following Traumatic Brain Injury. Neuroscience, 231:182–194. doi:10.1016/j.neuroscience.2012.12.002.

78. Titus DJ, Sakurai A, Kang Y, Furones C, Jergova S, Santos R, Sick TJ and Atkins CM  (2013)  Phosphodiesterase inhibition rescues chronic cognitive deficits induced by traumatic brain injury.  J. Neurosci., 33:5216-5226.

77. Villers A and Ris L  (2013)  Improved Preparation and Preservation of Hippocampal Mouse Slices for a Very Stable and Reproducible Recording of Long-term Potentiation.  JoVE (Journal of Visualized Experiments), doi: 10.3791/50483.

76.  Whitehead G, Jo J, Hogg EL, Piers T, Kim D-H, Seaton G, Seok H, Bru-Mercier G, Son GH, Regan P, Hildebrandt L, Waite E, Kim B-C, Kerrigan TL, Kim K, Whitcomb DJ, Collingridge GL, Lightman SL and Cho K  (2013)  Acute stress causes rapid synaptic insertion of Ca2+-permeable AMPA receptors to facilitate long-term potentiation in the hippocampus.  Brain, 136:3753–3765.

 

 

2012   WinLTP

  • 75. Ceolin L, Bortolotto ZA, Bannister N, Collingridge GL, Lodge D and Volianskis A  (2012)  A novel anti-epileptic agent, perampanel, selectively inhibits AMPA receptor-mediated synaptic transmission in the hippocampus.  Neurochemistry International, 61:517-522.

74. Clarke VRJ, Collingridge GL, Lauri SE and Taira T  (2012)  Synaptic kainate receptors in CA1 interneurons gate the threshold of theta-frequency-induced long-term potentiation.  J. Neurosci., 32:18215-18226.

73. Colotta V, Lenzi O, Catarzi D, Varano F, Squarcialupi L, Costagli C, Galli A, Ghelardini C, Pugliese AM, Maraula G, Coppi E, Pellegrini-Giampietro DE, Pedata F, Sabbadin D and Moro S  (2012)  3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studies.  Eur. J. Med. Chem., 54:470–482.

72. Dias RB, Ribeiro JA and Sebastião AM  (2012)  Enhancement of AMPA currents and GluR1 membrane expression through PKA-coupled adenosine A2A receptors.  Hippocampus, 22:276–291.

71. Diógenes MJ, Dias RB, Rombo DM, Miranda HV, Maiolino F, Guerreiro P, Näsström T, Franquelim HG, Oliveira LMA, Castanho MARB, Lannfelt L, Bergström J, Ingelsson M, Quintas A, Sebastião AM, Lopes LV and Outeiro TF  (2012)  Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.  J. Neurosci., 32:11750-11762.

70. Freret T, Billard J-M, Schumann-Bard P, Dutar P, Dauphin F, Boulouard M and Bouet V  (2012)  Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan.  Neurobiology of Aging, 33:1005.e1–1005.e10.

69. Irvine MW, Costa BM, Dlaboga D, Culley GR, Hulse R, Scholefield CL, Atlason P, Fang G?, Eaves R, Morley R, Mayo-Martin MB, Amici M, Bortolotto ZA, Donaldson L, Collingridge GL, Molnar E, Monaghan DT, Jane DE (2012) Piperazine-2,3-dicarboxylic Acid Derivatives as Dual Antagonists of NMDA and GluK1-Containing Kainate Receptors. J. Med. Chem., 55:327-341.

68. Haxaire C, Turpin FR, Potier B, Kervern M, Sinet P-M, Barbane G, Mothet J-P, Dutar P, Billard J-M (2012) Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting d-serine-dependent NMDA receptor activation. Aging Cell, 11:336–344.

67. Hradetzky E, Sanderson TM, Tsang TM, Sherwood JL, Fitzjohn SM, Lakics V, Malik N, Schoeffmann S, O'Neill MJ, Cheng TMK, Harris LW, Rahmoune H, Guest PC, Sher E, Collingridge GL, Holmes E, Tricklebank MD and Bahn S  (2012) The Methylazoxymethanol Acetate (MAM-E17) Rat Model: Molecular and Functional Effects in the Hippocampus.  Neuropsychopharmacology, 37:364–377

66. Huang Y, Yang S, Hu Z-Y, Liu G, Zhou W-X and Zhang Y-X  (2012)  A new approach to location of the dentate gyrus and perforant path in rats/mice by landmarks on the skull  Acta Neurobiol. Exp., 468–472.

65. Huang Y, Zhang H, Yang S, Qiao H, Zhou W and Zhang Y  (2012)  Liuwei Dihuang decoction facilitates the induction of long-term potentiation (LTP) in senescence accelerated mouse/prone 8 (SAMP8) hippocampal slices by inhibiting voltage-dependent calcium channels (VDCCs) and promoting N-methyl-d-aspartate receptor (NMDA) receptors. J. Ethnopharm., 140:384–390.

64.  Huupponen, J, Molchanova SM, Lauri SE and Taira T  (2012)  Ongoing intrinsic synchronous activity is required for the functional maturation of CA3-CA1 glutamatergic synapses.  Cerebral Cortex, doi: 10.1093/cercor/bhs262.

63. Jain S, Yoon SY, Zhu L, Brodbeck J, Dai J, Walker D, Huang Y  (2012)  Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development.  PLoS ONE 7(9): e46340. doi:10.1371/journal.pone.0046340.

62. Kaindl AM, Degos V, Peineau S, Gouadon E, Chhor V, Loron G, Le Charpentier T, Josserand J, Ali C, Vivien D, Collingridge GL, Lombet A, Issa L, Rene F, Loeffler JP, Kavelaars A, Verney C, Mantz J and Gressens P  (2012)  Activation of microglial N-methyl-D-aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain.  Ann. Neurology, 72:536–549.

61. Kratzer S, Mattusch C, Kochs E, Eder M, Haseneder R and Rammes Gerhard  (2012)  Xenon Attenuates Hippocampal Long-term Potentiation by Diminishing Synaptic and Extrasynaptic N-methyl-D-aspartate Receptor Currents. Anesthesiology, 116:673-682.

  • 60. Lucas SJ, Bortolotto ZA, Collingridge GL and Lodge D  (2012)  Selective activation of either mGlu2 or mGlu3 receptors can induce LTD in the amygdala.  Neuropharmacology, in press.

59. Luchkina NV, Sallert M, Clarke VRJ, Taira T and Lauri SE  (2012)  Mechanisms underlying induction of LTP-associated changes in short-term dynamics of transmission at immature synapses.  Neuropharmacol., 67:494-502.

58. Muzzi M, Blasi F, Masi A, Coppi E, Traini C, Felici R, Pittelli M, Cavone L, Pugliese AM, Moroni F and Chiarugi A  (2012)  Neurological basis of AMP-dependent thermoregulation and its relevance to central and peripheral hyperthermia.  J. Cerebral Blood Flow & Metabolism, doi:10.1038/jcbfm.2012.157.

57. Nicolas CS, Peineau S, Amici M, Csaba Z, Fafouri A, Javalet C, Collett VJ, Hildebrandt L, Seaton G, Choi S-L, Sim S-E, Bradley C, Lee K, Zhuo M, Kaang B-K, Gressens P, Dournaud P, Fitzjohn SM, Bortolotto ZA, Cho K and Collingridge GL  (2012)  The JAK/STAT Pathway Is Involved in Synaptic Plascity.  Neuron, 73:374–390.

56. Nuritova F and Frenguelli BG  (2012)  Putative depolarisation-induced retrograde signalling accelerates the repeated hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampus via group I metabotropic glutamate receptors.  Neurosci., 222:159-172.

  • 55. Panaccione I, King R, Molinaro G, Riozzi B, Battaglia G, Nicoletti F and Bashir ZI  (2012) Constitutively active group I mGlu receptors and PKMzeta regulate synaptic transmission in developing perirhinal cortex.  Neuropharmacology, in press.

54. Parcq J, Bertrand T, Montagne A, Baron AF, Macrez R, Billard JM, Briens A, Hommet Y, Wu J, Yepes M, Lijnen HR, Dutar P, Anglés-Cano E and Vivien  (2012)  Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity.  Cell Death & Differentiation, 19:1983-1991.

53. Portelli J, Thielemans L, Ver Donck L, Loyens E, Coppens J, Aourz N, Aerssens J, Vermoesen K, Clinckers R, Schallier A, Michotte Y, Moechars D, Collingridge GL, Bortolotto ZA and Smolders I  (2012)  Inactivation of the constitutively active ghrelin receptor attenuates limbic seizure activity in rodents. Neurotherapeutics, 9:658-672.

52. Regnier V, Billard J-M, Gupta S, Potier B, Woerner S, Paly E, Aurelie Ledru, David S, Luilier S, Bizot J-C, Vacano G, Kraus JP, Patterson D, Kruger WD, Delabar JM, London J (2012) Brain Phenotype of Transgenic Mice Overexpressing Cystathionine b-Synthase. PLOS ONE, 7:e29056.

51. Romberg C, McTighe SM, Heath CJ, Whitcomb DJ, Cho K, Bussey TJ and Saksida LM  (2012)  False recognition in a mouse model of Alzheimer’s disease: rescue with sensory restriction and memantine.  Brain, doi:10.1093/brain/aws074.

50.  Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu G-Q, Palop JJ and Mucke L  (2014)  Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer’s disease model.  Proc. Nat Acad Sci., 109:2895-2903.

49. Sanderson TM, Cotel MC, O’Neill MJ, Tricklebank MD, Collingridge GL and Sher E  (2012)  Alterations in hippocampal excitability, synaptic transmission and synaptic plasticity in a neurodevelopmental model of schizophrenia.  Neuropharmacology, 62:1349-1358.

48. Scott   HL, Tamagnini F, Narduzzo KE, Howarth JL, Lee YB, Wong LF, Brown MW, Warburton EC, Bashir ZI and Uney JB  (2012)  MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex.  Eur. J Neurosci., 36: 2941–2948.

47. Sherwood JL, Amici M, Dargan SL, Culley GR, Fitzjohn SM, Jane DE, Collingridge GL, Lodge D, Bortolotto ZA  (2012)  Differences in kainate receptor involvement in hippocampal mossy fibre long-term potentiation depending on slice orientation.  Neurochemistry International, 61:482-489.

46. Shonesy BC, Thiruchelvam K, Parameshwaran K, Rahman EA, Karuppagounder SS, Huggins KW, Pinkert CA, Amina R,  Dhanasekaran M and Suppiramaniam V  (2012)  Central insulin resistance and synaptic dysfunction in intracerebroventricular-streptozotocin injected rodents.  Neurobiology of Aging, 33:430.e5– 430.e18.

45. Srivastava R, Kumar M, Peineau S, Csaba Z, Mani S, Gressens P, El Ghouzzi V  (2012)  Conditional induction of Math1 specifies embryonic stem cells to cerebellar granule neuron lineage and promotes differentiation into mature granule neurons.  Stem Cells,  31:652–665.

44. Supcun B, Ghadiri MK, Zeraati M, Stummer W, Speckmann EJ, Gorji A  (2012)  The effects of tetanic stimulation on plasticity of remote synapses in the hippocampus-perirhinal cortex-amygdala network.  Synapse, 66:965-974.

43. Titus DJ, Furones C, Kang Y,  Atkins CM  (2013)  Age-dependent alterations in cAMP signaling contribute to synaptic plasticity deficits following traumatic brain injury.  Neuroscience, 231:182-194.

42. Villers A, Godaux E, Ris L (2012) Long-Lasting LTP Requires Neither Repeated Trains for Its Induction Nor Protein Synthesis for Its Development. PLoS ONE 7(7): e40823. doi:10.1371/journal.pone.0040823

 

 

2011   WinLTP

41. Bartlett TE, Lu J and Wang YT  (2011)  Slice orientation and muscarinic acetylcholine receptor activation determine the involvement of N-methyl D-aspartate receptor subunit GluN2B in hippocampal area CA1 long-term depression.  Mol. Brain, 4:41.

40. Bouet V, Freret T, Dutar P, Billard J-M, Boulouard M (2011) Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals. Mechanisms of Ageing and Development, 132:240-248.

39. Caruana DA, Warburton ED, Bashir ZI (2011) Induction of Activity-Dependent LTD Requires Muscarinic Receptor Activation in Medial Prefrontal Cortex. J. Neurosci., 31:18464-18478.

38. Ceolin L, Kantamneni S, Barker GRI, Hanna L, Murray L, Warburton EC, Robinson ESJ, Monn JA, Fitzjohn SM, Collingridge GL,  Bortolotto ZA and Lodge D  (2011)  Study of Novel Selective mGlu2 Agonist in the Temporo-Ammonic Input to CA1 Neurons Reveals Reduced mGlu2 Receptor Expression in a Wistar Substrain with an Anxiety-Like Phenotype.  J. Neurosci., 31:6721– 6731.

37. Errico F, Nisticò R, Napolitano F, Mazzola C, Astone D, Pisapia T, Giustizieri M, D’Aniello A, Mercuri NB, Usiello A  (2011)  Increased d-aspartate brain content rescues hippocampal age-related synaptic plasticity deterioration of mice.  Neurobiol. Aging, 32:2229–2243.

36. Escobar M , Crouzin N , Cavalier M , Quentin J , Roussel J , Lanté F , Batista-Novais AR , Cohen-Solal C , De Jesus Ferreira M-C , Guiramand J , Barbanel G and Vignes M  (2011)  Early, Time-Dependent Disturbances of Hippocampal Synaptic Transmission and Plasticity After In Utero Immune Challenge.  Biol. Psychiatry, 70:992–999.

35. Gan J, Greenwood SM, Cobb SR and Bushell TJ  (2011)  Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2.  Brit. J. Pharmacol, 163:984-994.

34. Kim J-I, Lee H-R, Sim S, Baek J, Yu N-K, Choi J-H, Ko H-G, Lee Y-S, Park S-W, Kwak C, Ahn S-J, Choi SY, Kim H, Kim K-H,  Backx PH, Bradley CA, Kim E, Jang D-J, Lee K, Kim SJ, Zhuo M, Collingridge GL and Kaang B-K  (2011)  PI3Kg is required for NMDA receptor–dependent long-term depression and behavioral flexibility.  Nature Neuroscience, 14:1447–1454.

33.  Koch S, Molchanova SM, Wright AK, Edwards A, Cooper JD, Taira T, Gillingwater TH, Tyyne J (2011) Morphologic and Functional Correlates of Synaptic Pathology in the Cathepsin D Knockout Mouse Model of Congenital Neuronal Ceroid Lipofuscinosis. J. Neuropathology & Experimental Neurology, 70:1089-1096.

32. Min J-A, Lee H-R, Kim J-I, Jub A, Kim D-J, Kaang B-K  (2011)  Impairment of long-term potentiation in the hippocampus ofalcohol-treated OLETF rats.  Neuroscience Letters, 500:52-56.

31. Moult PR and Harvey J  (2011)  NMDA receptor subunit composition determines the polarity of leptin-induced synaptic plasticity.  Neuropharmacology, 61:924-936.

30. Sanderson TM, Collingridge GL and Fitzjohn SM  (2011)  Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs  Molecular Brain, 4:30.

29. Takahashi H, Arstikaitis P, Prasad T, Bartlett TE, Wang YT, Murphy TH and Craig AM  (2011)  Postsynaptic TrkC and Presynaptic PTPs Function as a Bidirectional Excitatory Synaptic Organizing Complex.  Neuron, 69, 287–303.

28. Weng S-M, McLeod F, Bailey MES and Cobb SR (2011)  Synaptic Plasticity Deficits in an Experimental Model of Rett Syndrome: Long-Term Potentiation Saturation and its Pharmacological Reversal.  Neuroscience 180:314–321.

 

 

2010   WinLTP

27. Armogida M, Giustizieri M, Zona C, Piccirilli S, Nisticò R, Mercuri NB  (2010)  N-ethyl lidocaine (QX-314) protects striatal neurons against ischemia: An in vitro electrophysiological study.  Synapse, 64:161-168.

26. Potier B, Billard J-M, Rivière S, Sinet P-M, Denis I, Champeil-Potokar G, Grintal B, Jouvenceau A, Kollen M, Dutar P  (2010)  Reduction in glutamate uptake is associated with extrasynaptic NMDA and metabotropic glutamate receptor activation at the hippocampal CA1 synapse of aged rats.  Aging Cell, 9:722–735.

25. Hoffman AF, Laaris N, Kawamura M, Masino SA, Lupica CR  (2010)  Control of Cannabinoid CB1 Receptor Function on Glutamate Axon Terminals by Endogenous Adenosine Acting at A1 Receptors.  J. Neurosci., 30:545-555.

24. Jo J, Son GH, Winters BL, Kim MJ, Whitcomb DJ, Dickenson BA, Lee Y-B, Futai K, Amici M, Sheng M, Collingridge GL and Cho K  (2010)  Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.  Nature, 13:1216–1224.

23. Kamsler A, McHugh TJ, Gerber D, Huang SY, Tonegawa S  (2010)  Presynaptic m1 muscarinic receptors are necessary for mGluR long-term depression in the hippocampus.  PNAS, 107:1618-1623.

22. Lagostena L, Rosato-Siri M, Onofrio M, Brandi R, Arisi I, Capsoni S, Franzot J, Cattaneo A, Cherubini E  (2010)  In the Adult Hippocampus, Chronic Nerve Growth Factor Deprivation Shifts GABAergic Signaling from the Hyperpolarizing to the Depolarizing Direction.  J. Neurosci., 30:885-893.

21. Moult PR, Cross A, Santos SD, Carvalho A-L, Lindsay Y, Connolly CN, Irving AJ, Leslie NR, Harvey J  (2010)  Leptin Regulates AMPA Receptor Trafficking via PTEN Inhibition.  J. Neurosci., 30:4088-4101.

20. Villers A, Godaux E, Ris L  (2010)  Late phase of L-LTP elicited in isolated CA1 dendrites cannot be transferred by synaptic capture.  NeuroReport, 21:210-215.

 

 

2009   WinLTP

19. Dargan SL, Clarke VRJ, Alushin GM, Sherwood JL, Nistico R, Bortolotto ZA, Ogden AM, Bleakman D, Doherty AJ, Lodge D, Mayer ML, Fitzjohn SM, Jane DE, Collingridge GL  (2009)  ACET is a highly potent and specific kainate receptor antagonist: Characterisation and effects on hippocampal mossy fibre function.  Neuropharmacol., 56:121-130.

18. Hong I, Song B, Lee S, Kim J, Kim J, Choi S  (2009)  Extinction of cued fear memory involves a distinct form of depotentiation at cortical input synapses onto the lateral amygdala.  Eur. J. Neurosci., 30:2089-2099.

17. Karlen A, Karlsson TE, Mattsson A, Lundstromer K, Codeluppi S, Pham TM, Backman CM, Ogren SO, Aberg E, Hoffman AF, Sherling MA, Lupica CR, Hoffer BJ, Spenger C, Josephson A, Brene S, Olson L  (2009)  Nogo receptor 1 regulates formation of lasting memories.  PNAS, 106:20476-20481.

16. Kim J, Park S, Lee S and Choi S  (2009)  Amygdala depotentiation ex vivo requires mitogen-activated protein kinases and protein synthesis.  Neuroreport, 20:517-520.

15. Lagostena L, Danober L, Challal S, Lestage P,  Mocaër E, Trocmé-Thibierge C, Cherubini E  (2009)  Modulatory effects of S 38232, a non α-7 containing nicotine acetylcholine receptor agonist on network activity in the mouse hippocampus.  Neuropharmacol., 58:806-815.

14. Martella G, Tassone A, Sciamanna G, Platania P, Cuomo D, Viscomi MT, Bonsi P, Cacci E, Biagioni S, Usiello A, Bernardi G, Sharma N, Standaert DG, Pisani A  (2009)  Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.  Brain, 132:2336-2349.

13. Omrani A, Melone M, Bellesi M, Safiulina V, Aida T, Tanaka K, Cherubini E, Conti F  (2009)  Up-regulation of GLT-1 severely impairs LTD at mossy fibre-CA3 synapses.  J. Physiol., 587:4575-4587.

12. Peineau S, Nicolas CS, Bortolotto ZA, Bhat RV, Jonathan Ryves W, Harwood AJ, Dournaud P, Fitzjohn SM, Collingridge GL  (2009)  A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases.  Mol. Brain, 2:22 (10 pages).

11. Ris L, Villers A, Godaux E  (2009)  Synaptic capture-mediated long-lasting long-term potentiation is strongly dependent on mRNA translation.  NeuroReport, 20:1572-1576.

10. Sallert M, Rantamaki T, Vesikansa A, Anthoni H, Harju K, Yli-Kauhaluoma J, Taira T, Castren E, Lauri SE  (2009)  Brain-Derived Neurotrophic Factor Controls Activity-Dependent Maturation of CA1 Synapses by Downregulating Tonic Activation of Presynaptic Kainate Receptors.  J. Neurosci., 29:11294-11303.

9. Seoane A, Massey PV, Keen H, Bashir ZI, Brown MW  (2009)  L-Type Voltage-Dependent Calcium Channel Antagonists Impair Perirhinal Long-Term Recognition Memory and Plasticity Processes.  J. Neurosci., 29:9534-9544.

8. Zadran S, Qin Q, Bi X, Zadran H, Kim Y, Foy MR, Thompson R, Baudry M  (2009)  17-β-Estradiol increases neuronal excitability through MAP kinase-induced calpain activation PNAS, 106:21936-21941.

2008   WinLTP

7. Fernandes CC, Pinto-Duarte A, Ribeiro JA, and Sebastiao AM  (2008)  Postsynaptic action of brain-derived neurotrophic factor attenuates alpha7 nicotinic acetylcholine receptor-mediated responses in hippocampal interneurons.  J. Neurosci., 28:5611–5618.

6. Jo J, Heon S, Kim MJ, Son GH, Park Y, Henley JM, Weiss JL, Sheng M, Collingridge GL and Cho K  (2008)  Metabotropic Glutamate Receptor-Mediated LTD Involves Two Interacting Ca2+ Sensors, NCS-1 and PICK1.  Neuron, 60:1095-1111.

5. Lagostena L, Trocme-Thibierge C, Morain P and Cherubini E  (2008)  The partial a7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus.  Neuropharmacol., 54:676-685.

4. Giustizieri M, Armogida M, Berretta N, Federici M, Piccirilli S, Mercuri NB, Nistico R (2008)  Differential effect of carbamazepine and oxcarbazepine on excitatory synaptic transmission in rat hippocampus. Synapse 62:783–789.

3. Biber K, Pinto-Duarte A, Wittendorp MC, Dolga AM, Fernandes CC, Von Frijtag Drabbe Kunzel J, Keijser JN, de Vries R, Ijzerman AP, Ribeiro JA, Eisel U, Sebastião AM and Boddeke HWGM  (2008)  Interleukin-6 upregulates neuronal Adenosine A1 receptors: Implications for neuromodulation and neuroprotection.     Neuropsychopharmacol., 33:2237-2250.

 

2007

2. Lanté F, Meunier J, Guiramand J, Maurice T, Cavalier M, de Jesus Ferreira MC, Aimar R, Vignes M and Barbanel G (2007)  Neurodevelopmental damage after prenatal infection: Role of oxidative stress in the fetal brain.  Free Radical Biology and Medicine, 42:1231–1245.

1.  Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J, Lo E, Wu D, Saule E, Bouschet T, Matthews P, Isaac JTR, Bortolotto ZA, Wang YT, Collingridge GL  (2007)  UP inhibits LTD in the hippocampus via regulation of GSK3 beta. Neuron, 53:703-717.

 

 

 

 

LTP Program

The LTP Program has been used in at least 397 publications.  

 

 

2022  LTP Program

397. Chen C, Lu J, Peng W, Mak MSH, Yang Y, Zhu Z, Wang S, Hou J, Zhou X, Xin W, Hu Y, Tsim KWK, Han Y, Liu Q and Pi R (2022) Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model. Pharmacological Research, 175:106003; doi.org/10.1016/j.phrs.2021.106003. 

 

 

2021   LTP Program

396. Benassi SK, Alves JGSM, Guidoreni CG, Massant CG, Querioz CM, Garrido-Sanabria E, de Souza Loduca RD, Susemihl MA, Paiva WS, de Andrade AF, Teixeira MJ, Andrade JQ, Garzon E, Forest ML and Mello LE (2021) Two decades of research towards a potential first anti-epileptic drug. Seizure, 90:99-109; doi.org/10.1016/j.seizure.2021.02.031.

395. Coppi E, Buonvicino D, Ranieri G, Cherchi F, Venturini M, Pugliese AM and Chiarugi A *2921( Dexpramipexole Enhances K+ Currents and Inhibits Cell Excitability in the Rat Hippocampus In Vitro. Mol Neurobiol 58:2955–2962; doi.org/10.1007/s12035-021-02300-5. 

394. Dettori I, Fusco I, Bulli I, Gaviano L, Coppi E, Cherchi F, Venturini M, Di Cesare Mannelli L, Ghelardini C, Nocentini A, Supuran CT, Pugliese AM and Pedata F (2021) Protective effects of carbonic anhydrase inhibition in brain ischaemia in vitro and in vivo models. Journal of Enzyme Inhibition and Medicinal Chemistry, 36:964-976; doi.org/10.1080/14756366.2021.1907575.

393. Fan H, Sievert W, Hofmann J, Keppler SJ, Steiger K, Puig-Bosch X, Haller B, Rammes G and Multhoff G (2021) Partial-Brain Radiation-Induced Microvascular Cognitive Impairment in Juvenile Murine Unilateral Hippocampal Synaptic Plasticity.  International Journal of Radiation Oncology Biology Physics, doi.org/10.1016/j.ijrobp.2021.09.041. 

392. Ferrante A, Boussadia Z, Borreca A, Mallozzi C, Pedini G, Pacini L, Pezzola A, Armida M, Vincenzi F, Varani K, Bagni C, Popoli P and Martire A (2021) Adenosine A 2A receptor inhibition reduces synaptic and cognitive hippocampal alterations in Fmr1 KO mice.  Transl Psychiatry 11:112; doi.org/10.1038/s41398-021-01238-5.

391. Hauser J, Pisa E, Vásquez AA, Tomasi F, Traversa A, Chiodi V, Martin FP, Sprenger N, Lukjancenko O, Zollinger A, Metairon S, Schneider N, Steiner P, Martire A, Caputo V and Macrì S (2021) Sialylated human milk oligosaccharides program cognitive development through a non-genomic transmission mode. Mol Psychiatry, 26:2854–2871; doi.org/10.1038/s41380-021-01054-9.

490. Marshall P, Garton DR, Taira T, Võikar V, Vilenius C, Kulesskaya N, Rivera C and Andressoo JO (2021) Elevated expression of endogenous glial cell line‐derived neurotrophic factor impairs spatial memory performance and raises inhibitory tone in the hippocampus.  European Journal of Neuroscience, 53:2469-2482; https://doi.org/10.1111/ejn.15126.

389. Martire A, Pepponi R, Liguori F, Volonté C and Popoli P (2021) P2X7 Receptor Agonist 2′(3′)-O-(4-Benzoylbenzoyl) ATP Differently Modulates Cell Viability and Corticostriatal Synaptic Transmission in Experimental Models of Huntington’s Disease. Front. Pharmacol., doi.org/10.3389/fphar.2020.633861'

388. Pisa E, Martire A, Chiodi V, Traversa A, Caputo V, Hauser J and Macrì S (2021) Exposure to 3′ Sialyllactose-Poor Milk during Lactation Impairs Cognitive Capabilities in Adulthood. Nutrients, 13:4191; doi.org/10.3390/nu13124191.

387. Rodrigues NC, Silva‐Cruz A, Caulino-Rocha A, Bento-Oliveira A, Ribeiro JA and Cunha-Reis D (2021) Hippocampal CA1 theta burst‐induced LTP from weaning to adulthood: Cellular and molecular mechanisms in young male rats revisited.  European Journal of Neuroscience, 54:5272-5292; doi.org/10.1111/ejn.15390.

386. Wang H, Sun Y, Wu Y, Shen YJ, Xia J, Xu YH, Yue L, Sun L, Li XJ, Ma Y, Xiong YC and Li D (2021) MiR-30d Participates in Vincristine-Induced Neuropathic Pain by Down-Regulating GAD67. Neurochem Res, doi.org/10.1007/s11064-021-03462-3.

 

 

 2020   LTP Program

385. Rammes G and Parsons CG (2020) The Aβ aggregation modulator MRZ-99030 prevents and even reverses synaptotoxic effects of Aβ1-42 on LTP even following serial dilution to a 500: 1 stoichiometric.
Neuropharmacology, 179:108267; doi.org/10.1016/j.neuropharm.2020.108267.

384. Mai JZ, Liu C, Huang Z, Mai CL, Zhou X and Liu XG (2020) Oral application of bulleyaconitine A attenuates morphine tolerance in neuropathic rats by inhibiting long-term potentiation at C-fiber synapses and protein kinase C gamma in spinal dorsal horn. Molecular Pain, doi.org/10.1177/1744806920917242.

383. Huang Z, Zhou X, Zhang J, Mai CL, Mai JZ, Liu C, Zhang H and Liu XG  (2020)  Bulleyaconitine A inhibits itch and itch sensitization induced by histamine and chloroquine. Neuroscience, 429:68-77; doi.org/10.1016/j.neuroscience.2019.12.048.

382. Miranda-Lourenço C, Duarte ST, Palminha C, Gaspar C, Rodrigues TM, Magalhães-Cardoso T, Reia N, Colino-Oliveira M, Gomes R, Ferreira S, Rosa J, Xapelli S, Armstrong J, García-Cazorla A, Correia-de-Sá P, Sebastião AM and Diógenes MJ (2020) Impairment of adenosinergic system in Rett syndrome: Novel therapeutic target to boost BDNF signalling. Neurobiology of Disease, 145:105043; doi.org/10.1016/j.nbd.2020.105043. 

 

 

2019   LTP Program

381.  Fusco I, Cherchi F, Catarzi D, Colotta V, Varano F, Pedata F, Pugliese AM and Coppi E  (2019)  Functional characterization of a novel adenosine A2B receptor agonist on short-term plasticity and synaptic inhibition during oxygen and glucose deprivation in the rat CA1 hippocampus. Brain Research Bulletin, 151:174-180; doi.org/10.1016/j.brainresbull.2019.05.018.

380.  Martire A, Lambertucci C, Pepponi R, Ferrante A, Benati N, Buccioni M, Ben DD, Marucci G, Klotz K-N, Volpini R and Popoli P  (2019)  Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia. Journal of Neurochemistry, ttps://doi.org/10.1111/jnc.14660.

379.  Ryskamp D, Wu L, Wu J, Kim D, Rammes G, Geva M, Hayden M and Bezprozvanny I  (2019)  Pridopidine stabilizes mushroom spines in mouse models of Alzheimer's disease by acting on the sigma-1 receptor.   Neurobiology of Disease, 124:489-504; https://doi.org/10.1016/j.nbd.2018.12.022.

 

 

2018      LTP Program

378.  Coppi E, Lana D, Cherchi F, Fusco I, Buonvicino D, Urru M, Ranieri G, Muzzi M, Iovino L, Giovannini MG, Pugliese AM and Chiarugi A  (2018)  Dexpramipexole enhances hippocampal synaptic plasticity and memory in the rat. Neuropharmacology, 143:306-316.

377.  Dias RB, Rodrigues TM, Rombo DM, Ribeiro FF, Rodrigues J, McGarvey J, Orcinha C, Henley JM, Sebastião AM  (2018)
Erythropoietin Induces Homeostatic Plasticity at Hippocampal Synapses.  Cerebral Cortex, 28:2795–2809, doi.org/10.1093/cercor/bhx159.

376.  Fusco I, Ugolini F, Lana D, Coppi E, Dettori I, Gaviano L, Nosi D, Cherchi F, Pedata F, Giovannini MG and Pugliese AM  (2018)  The selective antagonism of adenosine A2B receptors reduces the synaptic failure and neuronal death induced by oxygen and glucose deprivation in rat CA1 Hippocampus in Vitro.  Frontiers in Pharmacology, 2018; 9: 399;doi:10.3389/fphar.2018.00399.

375.  Rammes G, Seeser F, Mattusch K, Zhu K, Haas L, Kummer M, Heneka M, Herms J and Parsons CG  (2018)  The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aß) species on long-term potentiation (LTP).  Neuropharmacology, 140:184-192.

374.  Tanqueiro SR, Ramalho RM, Rodrigues TM, Lopes LV, Sebastião AM and Diógenes MJ  (2018)  Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid ß. Frontiers in Pharmacology, doi.org/10.3389/fphar.2018.00237.

 

 

2017   LTP Program

373.  Aidil-Carvalho MF, Carmo AJS, Ribeiro JA and Cunha-Reisa D  (2017)  Mismatch novelty exploration training enhances hippocampal synaptic plasticity: A tool for cognitive stimulation?  Neurobiology of Learning and Memory, 145:240–250; doi.org/10.1016/j.nlm.2017.09.004.

372.  Bhagya VR, Srikumar BN, Veena J, Rao BSS  (2017)  Short-term exposure to enriched environment rescues chronic stress-induced impaired hippocampal synaptic plasticity, anxiety, and memory deficits.  J. Neurosci. Res., 95:1602-1610; doi.org/10.1002/jnr.23992.

371.  Dias RB, Rodrigues TM, Rombo DM, Ribeiro FF, Rodrigues J, McGarvey J, Orcinha C, Henley JM and Sebastião AM (2017)  Erythropoietin Induces Homeostatic Plasticity at Hippocampal Synapses.  Cerebral Cortex, doi.org/10.1093/cercor/bhx159.

370.  Ling Y-Z, Li Z-Y, Ou-Yang H-D, Ma C, Wu S-L, Wei J-Y, Ding H-H, Zhang X-L, Liu M, Liu C-C, Huang Z-Z, Xin W-J (2017)  The inhibition of spinal synaptic plasticity mediated by activation of AMP-activated protein kinase signaling alleviates the acute pain induced by oxaliplatin.  Experimental Neurology, 288:85-93; doi.org/10.1016/j.expneurol.2016.11.009.

369.  Poli D, Falsini M, Varano F, Betti M, Varani K, Vincenzi F, Pugliese AM, Pedata F, Ben DD, Thomas A, Palchetti A, Bettazzi F, Catarzi D and Colotta V  (2017)  Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A3 and A2A subtypes.  European Journal of Medicinal Chemistry, 125:611-628; doi.org/10.1016/j.ejmech.2016.09.076.

368.  Rammes G, Mattusch C, Wulff M, Seeser F, Kreuzer M, Zhu K, Deussing JM, Herms J and Parsons CG  (2017)Involvement of GluN2B subunit containing N-methyl-d-aspartate (NMDA) receptors in mediating the acute and chronic synaptotoxic effects of oligomeric amyloid-beta (Aß) in murine models of Alzheimer's disease (AD).  Neuropharmacology, 123:100-115; doi.org/10.1016/j.neuropharm.2017.02.003.

367.  Santos VV, Stark R, Rial D, Silva HB, Bayliss JA, Lemus MB, Davies JS, Cunha RA, Prediger RD and Andrews ZB (2017)  Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid ß (Aß1-40) administration in mice.  Journal of Neuroendocrinology, vol 29; doi.org/10.1111/jne.12476.

366.  Wei J-Y, Liu C-C, Ouyang H-D, Ma C, Xie M-X, Liu M, Lei W-L, Ding H-H, Wu S-L and Xin W-J  (2017)  Activation of RAGE/STAT3 pathway by methylglyoxal contributes to spinal central sensitization and persistent pain induced by bortezomib.  Experimental Neurology, 296:74-82; doi.org/10.1016/j.expneurol.2017.07.010.

365.  Xu T, Li D, Zhou X, Ouyang H-D, Zhou L-J, Zhou H, Zhang H-M, Wei X-H, Liu G and Liu X-G  (2017)  Oral Application of Magnesium-l-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-a/Nuclear Factor-?B Signaling.  Anesthesiology, 126:1151-1168; doi:10.1097/ALN.0000000000001601.

364.  Xu T, Zhang X-L, Ou-Yang, H-D, Li Z-Yu, Liu C-C, Huang Z-Z, Xu J, Wei J-Y, Nie B-L, Ma C, Wu S-L and Xin W-J (2017)  Epigenetic upregulation of CXCL12 expression mediates antitubulin chemotherapeutics–induced neuropathic pain. Pain, 158:637–648; doi: 10.1097/j.pain.0000000000000805.

363.  Zhou Y, Wang Z, Xia M, Zhuang S, Gong X, Pan J, Lia C, Fan R, Pang Q and Lu S  (2017)  Neurotoxicity of low bisphenol A (BPA) exposure for young male mice: Implications for children exposed to environmental levels of BPA. Environmental Pollution, 229:40-48, doi.org/10.1016/j.envpol.2017.05.043.

 

 

2016   LTP Program

362.  Abouelela A and Wieraszko A  (2016)  The Influence of Glutamate on Axonal Compound Action Potential In Vitro.  J. Brachial Plexus Peripheral Nerve Injury, 11:e29–e37; doi:10.1055/s-0036-1593441.

361.  Capsoni S, Malerba F, Carucci NM, Rizzi C, Criscuolo C, Origlia N, Calvello M, Viegi A, Meli G and Cattaneo A (2016)The chemokine CXCL12 mediates the anti-amyloidogenic action of painless human nerve growth factor.  Brain, 140:201–217; doi.org/10.1093/brain/aww271.

360.  Lemos C, Rial D, Gonçalves FQ, Pires J, Silva HB, Matheus FC, da Silva AC, Marques JM, Rodrigues RJ, Jarak I, Prediger RD, Reis F, Carvalho RA, Pereira FC and Cunha RA  (2016)  High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus. Neuroscience, 315:196-205; doi.org/10.1016/j.neuroscience.2015.12.018.

359.  Mahati K, Bhagya V, Christofer T, Sneha A and Rao BSS  (2016)  Enriched environment ameliorates depression-induced cognitive deficits and restores abnormal hippocampal synaptic plasticity.  Neurobiology of Learning and Memory, 134:379-391; doi.org/10.1016/j.nlm.2016.08.017.

358.  Matheus FC, Rial D, Real JI, Lemos C, Ben J, Guaita GO, Pita IR, Sequeira AC, Pereira FC, Walz R, Takahashi RN, Bertoglio LJ, Cunha CD, Cunha RA and Prediger RD  (2016)  Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats.  Behavioural Brain Research, 301:43-54; doi.org/10.1016/j.bbr.2015.12.011.

357.  Monteiro S, Ferreira FM, Pinto V, Roque S, Morais M, de Sá-Calçada D, Mota C, Correia-Neves M and Cerqueira JJ (2016)  Absence of IFN? promotes hippocampal plasticity and enhances cognitive performance.  Translational Psychiatry, 6:e707; doi:10.1038/tp.2015.194.

356.  Pinto I, Serpa A, Sebastião AM and Cascalheira JF  (2016)  The Role of cGMP on Adenosine A1 Receptor-mediated Inhibition of Synaptic Transmission at the Hippocampus.  Front. Pharmacol., 22 April 2016, doi.org/10.3389/fphar.2016.00103.

 

 

2015   LTP Program

355.  Ahmed Z and Wieraszko A  (2015)  Pulsed magnetic stimulation modifies amplitude of action potentials in vitro via ionic channels-dependent mechanism. Bioelectromagnetics, 36:386–397, DOI: 10.1002/bem.21917.

354.  Bhagya V, Srikumar BN, Raju TR and Shankaranarayana Rao BS  (2014)  The selective noradrenergic reuptake inhibitor reboxetine restores spatial learning deficits, biochemical changes, and hippocampal synaptic plasticity in an animal model of depression.  J. Neuroscience Research, vol 93; doi.org/10.1002/jnr.23473.

353.  Gonçalves FQ, Pires J, Pliassova A, Beleza R, Lemos C, Marques JM, Rodrigues RJ, Canas PM, Köfalvi A, Cunha RA and Rial D  (2015)  Adenosine A2b receptors control A1 receptor-mediated inhibition of synaptic transmission in the mouse hippocampus.  Eur. J. Neurosci., 41:878–888; DOI: 10.1111/ejn.12851.

352.  Luccarini I, Grossi C, Rigacci S, Coppi E, Pugliese AM, Pantano D, la Marca G, Dami TE, Berti A, Stefani M and Casamenti F (2015) Oleuropein aglycone protects against pyroglutamylated-3 amyloid-ß toxicity: biochemical, epigenetic and functional correlates. Neurobiology of Aging, 36:648–663; doi:10.1016/j.neurobiolaging.2014.08.029.

351.  Li W, Silva HB, Real J, Wang Y-M, Rial D, Li P, Payen M-P, Zhou Y, Muller CE, Tomé AR, Cunha RA and Chen J-F (2015)  Inactivation of adenosine A2A receptors reverses working memory deficits at early stages of Huntington's disease models. Neurobiology of Disease, 79:70–80; doi:10.1016/j.nbd.2015.03.030.

350.  Pál I, Kardos J, Dobolyi A and Héja L (2015) Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity. Molecular Brain, 8:35; DOI 10.1186/s13041-015-0127-9.

349.  Rammes G, Gravius A, Ruitenberg M, Wegener N, Chambon C, Sroka-Saidi K, Jeggo R, Staniaszek L, Spanswick D, O'Hare E, Palmer P, Kim E-M, Bywalez W, Egger V and Parsons CG  (2015) MRZ-99030 – A novel modulator of Aβ aggregation: II – Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice. Neuropharmacology, 92:170–182.

348.  Santos AR, Mele M, Vaz SH, Kellermayer B, Grimaldi M, Colino-Oliveira M, Rombo DM, Comprido D, Sebastião AM and Duarte CB (2015) Differential Role of the Proteasome in the Early and Late Phases of BDNF-Induced Facilitation of LTP. J. Neurosci., 35:3319-3329; doi: 10.1523/JNEUROSCI.4521-14.2015.

 

 

2014   LTP Program

347. Assaife-Lopes N, Sousa VC, Pereira DB, Ribeiro JA and Sebastião AM  (2014)  Regulation of TrkB receptor translocation to lipid rafts by adenosine A2A receptors and its functional implications for BDNF-induced regulation of synaptic plasticity.  Purinergic Signalling, 10:251–267.

346.  Cunha-Reis D, de Fatima Aidil-Carvalho M and Ribeiro JA  (2014)  Endogenous Inhibition of Hippocampal LTD and Depotentiation by Vasoactive Intestinal Peptide VPAC1 Receptors.  Hippocampus, DOI: 10.1002/hipo.22316.

345.  Ferrante A, Martire A, Pepponi R, Varani K, Vincenzi F, Ferraroc L, Beggiato S, Tebano MT and Popoli P  (2014)  Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease.  Neurobiology of Disease, 71:193–204.

344.  Fezza F, Marrone MC, Avvisati R, Di Tommaso M, Lanuti M, Rapino C, Mercuri NB, Maccarrone M and Marinelli S  (2014) Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting.  Molecular and Cellular Neuroscience 62:1–9.

343.  Jiang Y, Liu Y, Zhu C, Ma X, Ma L, Zhou L, Huang Q, Cen L, Pi R and Chen X (2015) Minocycline enhances hippocampal memory, neuroplasticity and synapse-associated proteins in aged C57 BL/6 mice. Neurobiology of Learning and Memory, 121:20–29, doi:10.1016/j.nlm.2015.03.003.

342.  Laing M and Bashir ZI  (2014)  β-Adrenoceptors and synaptic plasticity in the perirhinal cortex.  Neuroscience, 273:163-173.

341. Liu Q-Y, Wang C-Y, Cai Z-L, Xu S-T, Liu W-X, Xiao P and Li C-H  (2014)  Effects of intrahippocampal GABAB receptor antagonist treatment on the behavioral long-term potentiation and Y-maze learning performance.  Neurobiology of Learning and Memory, 114:26–31.

340. Luccarini I, Grossi C, Rigacci S, Coppi E, Pugliese AM, Pantano D, la Marca G, Dami TE, Berti A, Stefani M, Casamenti F  (2014)  Oleuropein aglycone protects against pyroglutamylated-3 Aß toxicity: biochemical, epigenetic and functional correlates.  Neurobiology of Aging, DOI: 10.1016/j.neurobiolaging.2014.08.029.

339.  Maraula G, Lana D, Coppi E, Gentile F, Mello T, Melani A, Galli A, Giovannini MG, Pedata F and Pugliese AM (2014) The Selective Antagonism of P2X7 and P2Y1 Receptors Prevents Synaptic Failure and Affects Cell Proliferation Induced by Oxygen and Glucose Deprivation in Rat Dentate Gyrus. PLOS|One, DOI: 10.1371/journal.pone.0115273.

338.  Nedden S, Doney AS and Frenguelli BG  (2014)  Modulation of intracellular ATP determines adenosine release and functional outcome in response to metabolic stress in rat hippocampal slices and cerebellar granule cells.  J. Neurochem., 128:111-124.

337.  Rial D, Castro AA, Machado N, Garção P, Gonçalves FQ, Silva HB, Tomé AR, Köfalvi A, Corti O, Raisman-Vozari R, Cunha RA and Prediger RD (2014) Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease. PLOS|One, DOI: 10.1371/journal.pone.0114216.

336.  Ribeiro PO, Tome´ AR, Silva HB, Cunha RA and Antunes LM  (2014)  Clinically relevant concentrations of ketamine mainly affect long-term potentiation rather than basal excitatory synaptic transmission and do not change paired-pulse facilitation in mouse hippocampal slices.  Brain Research, 1560:10–17.

 335.  Sousa VC, Vital J, Costenla AR, Batalha VL, Sebastião AM, Ribeiro JA and Lopes  lv  (2014)  Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats. Neurobiology of Aging, 35:1680-1685.

 

 

2013   LTP Program

334. Burnouf S, Martire A, Derisbourg M, Laurent C, Belarbi K, Leboucher A, Fernandez-Gomez FJ, Troquier L, Eddarkaoui S, Grosjean M-E, Demeyer D, Muhr-Tailleux A, Buisson A, Sergeant N, Hamdane M, Humez S, Popoli P, Buée L, Blum D  (2013)  NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model.  Aging Cell, 12:11–23.

333.  Ferreira AC, Pinto V, Dá Mesquita S, Novais A, Sousa JC, Correia-Neves M, Sousa N, Palha JA and Marques F  (2014)  Lipocalin-2 is involved in emotional behaviors and cognitive function.  Front. Cell Neurosci., 7:122.

332. Haseneder R, Starker L, Berkmann J, Kellermann K, Jungwirth B, Blobner M, Eder M, Kochs E and Rammes G (2013) Sevoflurane Anesthesia Improves Cognitive Performance in Mice, but Does Not Influence In Vitro Long-Term Potentation in Hippocampus CA1 Stratum Radiatum. PLoS ONE 8(5): e64732. doi:10.1371/journal.pone.0064732

331. Martire A, Pepponi R, Domenici MR, Ferrante A, Chiodi V, Popoli P  (2013)  BDNF prevents NMDA-induced toxicity in models of Huntington's disease: the effects are genotype specific and adenosine A2A receptor is involved.  J. Neurochem., 125:225-235.

330. Maraula G, Traini C, Mello T, Coppi E, Galli A, Pedata F, Pugliese AM  (2013)  Effects of oxygen and glucose deprivation on synaptic transmission in rat dentate gyrus: Role of A2A adenosine receptors.  Neuropharmacol., 67:511-520.

329. McLeod F, Ganley R, Williams L, Selfridge J, Bird A and Cobb SR  (2012)  Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome.  Neuroscience, 231:195-205.

328. Muzzi M, Coppi E, Pugliese AM and Chiarugi A  (2013)  Anticonvulsant effect of AMP by direct activation of adenosine A1 receptor.  Experimental Neurology, 250:189–193.

327. Pál I, Nyitrai G, Kardos J, Héja L  (2013)  Neuronal and astroglial correlates underlying spatiotemporal intrinsic optical signal in the rat hippocampal slice.  PLoS ONE 8(3): e57694. doi:10.1371/journal.pone.0057694.

326. Remenyi J, van den Bosch MWM, Palygin O, Mistry RB, McKenzie C, Macdonald A, Hutvagner G, Arthur JSC, Frenguelli BG and Pankratov (2013)  miR-132/212 Knockout Mice Reveal Roles for These miRNAs in Regulating Cortical Synaptic Transmission and Plasticity. PLoS ONE 8(4): e62509. doi:10.1371/journal.pone.0062509.

325. Rodi D, Buzzi A, Barbieri M, Zucchini S, Verlengia G, Binaschi A, Regoli D, Boschi A, Ongali B, Couture R, Simonato M  (2013)  Bradykinin B2 Receptors Increase Hippocampal Excitability And Susceptibility To Seizures In Mice.  Neuroscience, dx.doi.org/10.1016/j.neuroscience.2013.06.038.

 324.  Scattonia ML, Martire A, Cartoccia G, Ferrante A and Ricceri L  (2013)  Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+tf/J strain, a mouse model of autism.  Behavioural Brain Research, 251:35–40.

323. Tatini F, Pugliese AM, Traini C, Niccoli S, Maraula G, Dami TE, Mannini B, Scartabelli T, Pedata F, Casamenti F and Chiti F  (2013)  Amyloid-β oligomer synaptotoxicity is mimicked by oligomers of the model protein HypF-N.  Neurobiology of Aging, 34:2100–2109.

322. Uthayathas S, Parameshwaran K, Karuppagounder SS, Ahuja M, Dhanasekaran M, Suppiramaniam V  (2013)  Selective inhibition of phosphodiesterase 5 enhances glutamatergic synaptic plasticity and memory in mice. DOI: 10.1002/syn.21676.

321.  Wang J, Liu Y, Zhou L-J, Wu Y, Li F, Shen K-F, Pang R-P, Wei X-H, Li Y-Y and Liu X-G  (2013)  Magnesium L-threonate Prevents and Restores Memory Deficits Associated with Neuropathic Pain by Inhibition of TNF-α.  Pain Physician, 16:E563-E575.

 

 

2012   LTP Program

320.  Chiodi V, Uchigashima M, Beggiato S, Ferrante A, Armida M, Martire A, Potenza RL, Ferraro L, Tanganelli S, Watanabe M, Domenicia MR, Popolia P (2012) Unbalance of CB1 receptors expressed in GABAergic and glutamatergic neurons in a transgenic mouse model of Huntington's disease. Neurobiology of Disease, 45:983–991.

319.  Damborsky JC, Griffith WH and Winzer-Serhan UH  (2011)  Chronic neonatal nicotine exposure increases excitation in the young adult rat hippocampus in a sex-dependent manner.  Brain Res., 1430:8–17

318. Diógenes MJ, Neves-Tomé R, Fucile S, Martinello K, Scianni M, Theofilas P, Lopatář J, Ribeiro JA, Maggi L, Frenguelli BG, Limatola C, Boison D and Sebastião AM  (2012)  Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.  Cerebral Cortex, doi: 10.1093/cercor/bhs284.

317. Jacob W, Marsch R, Marsicano G, Lutz B and Wotjak CT  (2012)  Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo.  Neurobiology of Learning and Memory, 98:47-55.

316. Kanju PM, Parameshwaran K, Sims-Robinson C, Uthayathas S, Josephson EM, Rajakumar N, Dhanasekaran M, Suppiramaniam V  (2012)  Selective Cholinergic Depletion in Medial Septum Leads to Impaired Long Term Potentiation and Glutamatergic Synaptic Currents in the Hippocampus.  PLoS ONE, 7:e31073.

315. Maggio N and Segal M  (2012)  Cellular Basis of a Rapid Effect of Mineralocorticosteroid Receptors Activation on LTP in Ventral Hippocampal Slices.  Hippocampus, 22:267–275.

314. Park S-W, Jang H-J, Cho K-H, Kim M-J, Yoon SH, and Rhie D-J  (2012)  Developmental Switch of the Serotonergic Role in the Induction of Synpatic Long-term Potentiation in the Rat Visual Cortex.  Korean J Physiol Pharmacol., 16:65–70.

313. Perugini A, Laing M, Berretta N, Aicardi G, Bashir ZI  (2012)  Synaptic plasticity from amygdala to perirhinal cortex: a possible mechanism for emotional enhancement of visual recognition memory?  Eur. J. Neuroscience, 36:2421–2427.

312. Parameshwaran K, Buabeid MA, Karuppagounder SS, Uthayathas S, Thiruchelvam K, Shonesy B, Dityatev A, Escobar MC, Dhanasekaran M and Suppiramaniam V  (2012)  Developmental nicotine exposure induced alterations in behavior and glutamate receptor function in hippocampus.  Cell. Mol. Life Sci., 69:829–841

311.  Purkayastha S, Ford J, Kanjilal B (2012) Clozapine Functions Through the Prefrontal Cortex Serotonin 1A Receptor to Heighten Neuronal Activity via Calmodulin Kinase II?NMDA Receptor Interactions. J. Neurochem., 120:396-407.

310. Zhang H, Etherington L-A, Hafner A-S, Belelli D, Coussen F, Delagrange P, Chaouloff F, Spedding M, Lambert JJ, Choquet D and Groc L  (2012)  Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule.  Molecular Psychiatry, doi: 10.1038/mp.2012.80.

2011   LTP Program

309. Appleby VJ, Corrêa SAL, Duckworth JK, Nash JE, Noël J, Fitzjohn SM, Collingridge GL and Molnár E  (2011)  LTP in hippocampal neurons is associated with a CaMKII-mediated increase in GluA1 surface expression.  J. Neurochem., 116:530–543.

308. Bhagya V, Srikumar BN, Raju TR and Rao BSS  (2011)  Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression.  Psychopharmacology, 214:477–494.

307. Costenla AR, Diogenes MJ, Canas PM, Rodrigues RJ, Nogueira C, Maroco J, Agostinho PM, Ribeiro JA, Cunha RA and de Mendonca A  (2011)  Enhanced role of adenosine A2A receptors in the modulation of LTP in the rat hippocampus upon ageing.  European J. Neurosci., 34:12–21.

306. Diogenes MJ, Costenla AR, Lopes LV, Jeronimo-Santos A, Sousa VC, Fontinha BM, Ribeiro JA and Sebastiao AM  (2011)  Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF.  Neuropsychopharmacology, 36:1823–1836.

305. Ishikawa Y, Tamura H and Shiosaka S  (2011)  Diversity of neuropsin (KLK8)-dependent synaptic associativity in the hippocampal pyramidal neuron.  J Physiol 589:3559–3573.

304. Lopatár J, Dale N, Frenguelli BG  (2011)  Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: Evidence from purine biosensors and P2 receptor agonists and antagonists. Neuropharmacology, 61:25-34.

303. Maggio N and Segal M  (2011)  Persistent Changes in Ability to Express Long-Term Potentiation/Depression in the Rat Hippocampus After Juvenile/Adult Stress.  Biol. Psychiatry, 69:748–753.

302. Martire A, Tebano MT, Chiodi V, Ferreira SG, Cunha RA, Köfalvi A and Popoli P  (2011)  Pre-synaptic adenosine A2A receptors control cannabinoid CB1 receptor-mediated inhibition of striatal glutamatergic neurotransmission.  J. Neurochem., 116:273–280.

301. Moreno E, Vaz SH, Cai N-S, Ferrada C, Quiroz C, Barodia SK, Kabbani N, Canela EI, McCormick PJ, Lluis C, Franco R, Ribeiro JA, Sebastiao AM and Ferre S  (2011)  Dopamine–Galanin Receptor Heteromers Modulate Cholinergic Neurotransmission in the Rat Ventral Hippocampus.  J. Neurosci., 31:7412–7423.

300. Morini R, Mlinar B, Baccini G, Corradetti R  (2011)  Enhanced hippocampal long-term potentiation following repeated MDMA treatment in Dark–Agouti rats.  Eur. Neuropsychopharmacology,  21:80-91.

299. Nistico R, Dargan SL, Amici M, Collingridge GL and Bortolotto ZA  (2011)  Synergistic interactions between kainate and mGlu receptors regulate bouton Ca21 signalling and mossy fibre LTP.  Scientific Reports, Volume:1, Article number:103 DOI:doi:10.1038/srep00103.

298. Rammes G, Hasenjäger A, Sroka-Saidi K, Deussing JM, Parsons CG  (2011)  Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of b-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.  Neuropharmacology, 60:982-990.

297. Ren W-J, Liu Y, Zhou L-J, Li W, Zhong Y, Pang R-P, Xin W-J, Wei X-H, Wang J, Zhu H-Q, Wu C-Y, Qin Z-H, Liu G and Liu X-G  (2011)  Peripheral Nerve Injury Leads to Working Memory Deficits and Dysfunction of the Hippocampus by Upregulation of TNF-a in Rodents.  Neuropsychopharmacology, 36:979–992.

296. Spalloni A, Origlia N, Sgobio C, Trabalza A, Nutini M, Berretta N, Bernardi G, Domenici L, Ammassari-Teule M and Longone P  (2011)  Postsynaptic Alteration of NR2A Subunit and Defective Autophosphorylation of alphaCaMKII at Threonine-286 Contribute to Abnormal Plasticity and Morphology of Upper Motor Neurons in Presymptomatic SOD1G93A Mice, a Murine Model for Amyotrophic Lateral Sclerosis.  Cerebral Cortex, 21:796-805.

295. Traini C, Pedata F, Cipriani S, Mello T, Galli A, Giovannini MG, Cerbai F, Volpini R, Cristalli G and Pugliese AM  (2011)  P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase12 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro.  Eur. J. Neurosci., 33:2203–2215.

294. Venerosi A, Martire A, Rungi A, Pieri M, Ferrante A, Zona C, Popoli P and Calamandrei G  (2011)  Complex behavioral and synaptic effects of dietary branched chain amino acids in a mouse model of amyotrophic lateral sclerosis.  Mol. Nutr. Food Res., 55:541–552.

293. Zhou L-J, Yang T, Wei X, Liu Y, Xin W-J, Chen Y, Pang R-P, Zang Y, Li Y-Y and Liu X-G  (2011)  Brain-derived neurotrophic factor contributes to spinal long-term potentiation and mechanical hypersensitivity by activation of spinal microglia in rat.  Brain, Behavior, and Immunity, 25:322–334.

 

 

2010   LTP Program

292. Assaife-Lopes N, Sousa VC, Pereira DB, Ribeiro JA, Chao MV, Sebastião AM (2010)  Activation of Adenosine A2A Receptors Induces TrkB Translocation and Increases BDNF-Mediated Phospho-TrkB Localization in Lipid Rafts: Implications for Neuromodulation.  J. Neurosci., 30:8468-8480.

291. Bouet V, Freret T, Dutar P, Billard J-M and Boulouard M  Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals.  Mechanisms of Ageing and Development, 132:240–248.

290. Ferrante A, Martire A, Armida M, Chiodi V, Pezzola A, Potenza RL, Domenici MR, Popoli P  (2010)  Influence of CGS 21680, a selective adenosine A(2A) receptor agonist, on NMDA receptor function and expression in the brain of Huntington's disease mice.  Brain Res., 1323:184-191.

289. Jang H-J, Cho K-H, Park S-W, Kim M-J, Yoon SH and Rhie D-J  (2010)  Effects of Serotonin on the Induction of Long-term Depression in the Rat Visual Cortex.  Korean J Physiol Pharmacol., 14:337-343.

288. Jo J, Son GH, Winters BL, Kim MJ, Whitcomb DJ, Dickinson BA, Lee Y-B, Futai K, Amici M, Sheng M, Collingridge GL and  Cho K  (2010)  Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.  Nature Neuroscience, 13:1216-1226.

287. Kim J, Song B, Hong I, Kim J, Lee J, Park S, Eom JY, Lee CJ, Lee S and Choi S  (2010)  Reactivation of Fear Memory Renders Consolidated Amygdala Synapses Labile.  J. Neurosci., 30:9631-9640.

286. Li Z, Jo J, Jia JM, Lo SC, Whitcomb DJ, Jiao S, Cho K, Sheng M  (2010)  Caspase-3 Activation via Mitochondria Is Required for Long-Term Depression and AMPA Receptor Internalization.  Cell, 141:859-871.

285. Martinez-Coria H, Green KN, Billings LM, Kitazawa M, Albrecht M, Rammes G, Parsons CG, Gupta S, Banerjee P, LaFerla FM  (2010)  Memantine Improves Cognition and Reduces Alzheimer's-Like Neuropathology in Transgenic Mice.  Am J. Pathology, 176:870-880.

284. Martire A, Ferrante A, Potenza RL, Armida M, Ferretti R, Pezzola A, Domenici MR, Popoli P  (2010)  Remodeling of striatal NMDA receptors by chronic A(2A) receptor blockade in Huntington's disease mice.  Neurobiol. Disease, 37:99-105.

283. Nash JE, Appleby VJ, Correa SAL, Wu H, Fitzjohn SM, Garner CC, Collingridge GL, Molnar E  (2010)  Disruption of the interaction between myosin VI and SAP97 is associated with a reduction in the number of AMPARs at hippocampal synapses.  J. Neurochem., 112:677-690.

282. Origlia N, Bonadonna C, Rosellini A, Leznik E, Arancio (2010), ShiDu Yan S and Domenici L  (2010)  Microglial Receptor for Advanced Glycation End Product-Dependent Signal Pathway Drives β-Amyloid-Induced Synaptic Depression and Long-Term Depression Impairment in Entorhinal Cortex  J. Neurosci., 30:11414-11425.

281. Valderrama-Gonzalez GD, Gasson MN, Warwick K and Whalley BJ  (2010)  Prosthesis grasp reflex via peripheral nerve control — An in vitro study. Cybernetic Intelligent Systems (CIS), 2010 IEEE 9th International Conference on,  p 1-6.

280. Zhong Y, Zhou L-J, Ren W-J, Xin W-J, Li Y-Y, Zhang T, Liu X-G  (2010)  The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: The role of tumor necrosis factor-α.  Brain, Behavior & Immunity, 24:874–880.

279. Zhou L-J, Ren W-J, Zhong Y, Yang T, Wei X-H, Xin W-J, Liu C-C, Zhou L-H, Li Y-Y, Liu X-G  (2010)  Limited BDNF contributes to the failure of injury to skin afferents to produce a neuropathic pain condition.  Pain, 148:148-157.

 

 

2009   LTP Program

278. Ahmed Z, Wieraszko A  (2009)  The Influence of Pulsed Magnetic Fields (PMFs) on Nonsynaptic Potentials Recorded From the Central and Peripheral Nervous Systems In Vitro.  Bioelectromagnetics, 30:621-630.

277. Amantea D, Marrone MC, Nistico R, Federici M, Bagetta G, Bernardi G, Mercuri NB  (2009)  Oxidative Stress in Stroke Pathophysiology: Validation of Hydrogen Peroxide Metabolism as a Pharmacological Target to Afford Neuroprotection.  Conference Information: Workshop on Apoptosis in Biology and Medicine, SEP 12-15, 2008 Tohoku Pharmaceut Univ, Sendai, JAPAN.  Advances in Neuropharmacology  Book Series: International Review of Neurobiology, 85:363-+.

276. Colotta V, Lenzi O, Catarzi D, Varano F, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Traini C, Pedata F, Morizzo E and  Moro S  (2009)  Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a New Scaffold To Develop Potent and Selective Human A3 Adenosine Receptor Antagonists. Synthesis, Pharmacological Evaluation, and Ligand−Receptor Modeling Studies.  J. Med. Chem., 52:2407–2419.

275. Dickinson BA, Jo J, Seok H, Son GH, Whitcomb DJ, Davies CH, Sheng M, Collingridge GL, Cho K  (2009)  A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-α.  Mol. Brain, 2:18 (12 pages).

274. Etherington LAV, Patterson GE, Meechan L, Boison D, Irving AJ, Dale N, Frenguelli BG  (2009)  Astrocytic adenosine kinase regulates basal synaptic adenosine levels and seizure activity but not activity-dependent adenosine release in the hippocampus.  Neuropharmacol., 56:429-437.

273. Gurevicius K, Kuang F, Stoenica L, Irintchev A, Gureviciene I, Dityatev A, Schachner M, Tanila H  (2009) Genetic Ablation of Tenascin-C Expression Leads to Abnormal Hippocampal CA1 Structure and Electrical Activity In Vivo.  Hippocampus, 19:1232-1246.

272. Haseneder R, Kratzer S, von Meyer L, Eder M, Kochs E, Rammes G  (2009)  Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation.  Eur. J. Pharmacol., 623:47-51.

271. Jang HJ, Cho KH, Kim HS, Hahn SJ, Kim MS, Rhie DJ  (2009)  Age-Dependent Decline in Supragranular Long-Term Synaptic Plasticity by Increased Inhibition During the Critical Period in the Rat Primary Visual Cortex.  J. Neurophysiol., 101:269-275.

270. Krüger K, Straub H, Hirner AV, Hippler J, Binding N and Muβhoff U  (2009)  Effects of monomethylarsonic and monomethylarsonous acid on evoked synaptic potentials in hippocampal slices of adult and young rats.  Toxicology and Applied Pharmacol., 236:115–123.

269. Moult PR, Milojkovic B and Harvey J  (2009)  Leptin reverses long-term potentiation at hippocampal CA1 synapses.  J. Neurochem., 108:685-696.

268. Pugliese AM, Traini C, Cipriani S, Gianfriddo M, Mello T, Giovannini MG, Galli A and Pedata F  (2009)  The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.  Br. J. Pharmacol., 157:818-830.

267. Origlia N, Capsoni S, Cattaneo A, Fang F, Arancio O, Yan SD, Domenici L  (2009)  A beta-Dependent Inhibition of LTP in Different Intracortical Circuits of the Visual Cortex: The Role of RAGE.  J. Alzheimers Disease, 17:59-68.

266. Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S,  Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp, HJ  (2009)   The Insulin Receptor Substrate of 53 kDa (IRSp53) Limits Hippocampal Synaptic Plasticity.  J. Biol. Chem., 284:9225-9236.

265. Serpa A, Ribeiro JA, Sebastiao AM  (2009)  Cannabinoid CB1 and adenosine A(1) receptors independently inhibit hippocampal synaptic transmission.  Eur. J. Pharmacol., 623:41-46.

264. Sheroziya MG, von Bohlen und Halbach O, Unsicker K, Egorov AV  (2009)  Spontaneous Bursting Activity in the Developing Entorhinal Cortex.  J. Neurosci., 29:12131-12144.

263. Tebano MT, Martire A, Chiodi V, Pepponi R, Ferrante A, Domenici MR, Frank C, Chen J-F, Ledent C, Popoli P  (2009)  Adenosine A(2A) receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.  J. Neurochem., 110:1921-1930.

 

 

2008   LTP Program

262. Ahmeda Z, Wieraszko A  (2008)  The mechanism of magnetic field-induced increase of excitability in hippocampal neurons.  Brain Res., 1221:30–40.

261. Al-Hayani AA  (2008)  In Vitro Anticonvulsant Action of 2-Arachidonyl Glycerol.  JKAU: Med. Sci., 14:27-36.

260. Bortolotto ZA, Collett VJ, Conquet F, Jia Z  and Collingridge GL  (2008)  An analysis of the stimulus requirements for setting the molecular switch reveals a lower threshold for metaplasticity than synaptic plasticity.  Neuropharmacol., 55:454–458.

259. Colotta V, Catarzi D, Varano F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Traini C, Pugliese AM, Pedata F, Morizzod E and Morod S  (2008)  Synthesis, ligand–receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a] quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.  Bioorganic & Medicinal Chem., 16:6086–6102.

258. Errico F, Nistico R, Palma G, Federici M, Affuso A, Brilli E, Topo E, Centonze D, Bernardi G, Bozzi Y, D'Aniello A, Di Lauro R, Mercuri NB and Usiello A  (2008)  Increased levels of D-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility.  Mol. Cell. Neurosci., 37:236–246.

257. Fontinha BM, Diogenes MJ, Ribeiro JA, Sebastiao AM  (2008)  Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine.  Neuropharmacol., 54:924-933.

256. Ishikawa Y, Horii Y, Tamura H and Shiosaka S  (2008)  Neuropsin (KLK8)-Dependent and -Independent Synaptic Tagging in the Schaffer-Collateral Pathway of Mouse Hippocampus.  J. Neurosci., 28:843–849.

255. Hartley DM, Zhao C, Speier AC, Woodard GA, Li S and Walz T  (2008)  Transglutaminase Induces Protofibril-like Amyloid β-Protein Assemblies That Are Protease-resistant and Inhibit Long-term Potentiation.  J. Biol. Chem., 283:16790-16800.

254. Maggio N, Shavit E, Chapman J and Segal M  (2008)  Thrombin Induces Long-Term Potentiation of Reactivity to Afferent Stimulation and Facilitates Epileptic Seizures in Rat Hippocampal Slices: Toward Understanding the Functional Consequences of Cerebrovascular Insults.  J. Neurosci., 28:732–736.

253. Massey PV, Phythian D, Narduzzo K, Warburton EC, Brown MW, Bashir ZI  (2008)  Learning-specific changes in Long-Term Depression in adult perirhinal cortex.  J. Neurosci., 28:7548-7554.

252. Mistry RB, Isaac JTR and Crabtree JW  (2008)  Two differential frequency-dependent mechanisms regulating tonic firing of thalamic reticular neurons.  Eur.J. Neurosci., 27:2643–2656.

251. Mlinar B, Mascalchi S, Morini R, Giachi F and Corradetti R  (2007)  MDMA Induces EPSP–Spike Potentiation in Rat Ventral Hippocampus In Vitro Via Serotonin and Noradrenaline Release and Coactivation of 5-HT4 and b1 Receptors.  Neuropsychopharmacol., 33:1464-1475.

250. Moult PR, Correa SAL, Collingridge GL, Fitzjohn SM and Bashir ZI  (2008)  Co-activation of p38 mitogen-activated protein kinase and protein tyrosine phosphatase underlies metabotropic glutamate receptor-dependent long-term depression.  J. Physiol. 586:2499-2510.

249. Origlia N, Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt AM, Arancio O, Yan SD, and Domenici L  (2008)  Receptor for Advanced Glycation End Product-Dependent Activation of p38 Mitogen-Activated Protein Kinase Contributes to Amyloid--Mediated Cortical Synaptic Dysfunction.  J. Neurosci., 28:3521–3530.

248. Riekki R, Pavlov I, Tornberg J, Lauri SE, Airaksinen MS and Taira T  (2008)  Altered synaptic dynamics and hippocampal excitability but normal long-term plasticity in mice lacking hyperpolarizing GABAA receptor-mediated inhibition in CA1 pyramidal neurons.  J Neurophysiol 99:3075–3089.

247. Tanaka K and Augustine GJ  (2008)  A Positive Feedback Signal Transduction Loop Determines Timing of Cerebellar Long-Term Depression.  Neuron, 59:608-620.

246. Tebano MT; Martire A; Potenza RL; Gro C; Pepponi R; Armida M; Domenici MR; Schwarzschild MA; Chen JF; Popoli P  (2008)  Adenosine A2A receptors are required for normal BDNF levels and BDNF-induced potentiation of synaptic transmission in the mouse hippocampus.  J. Neurochem., 104:279-286.

245. Vlachos A, Maggio N and Segal M  (2008)  Lack of Correlation Between Synaptopodin Expression and the Ability to Induce LTP in the Rat Dorsal and Ventral Hippocampus.  Hippocampus, 18:1–4.

244. Wall MJ, Wigmore G, Lopatar J, Frenguelli BG and Dale N (2008)  The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition.  Neuropharmacol., 55:1251–1258.

243.  Xie W, Ramakrishna N, Wieraszko A, Hwang YW  (2008)  Promotion of Neuronal Plasticity by (–)-Epigallocatechin-3-Gallate.  Neurochem. Res., 33:776–783.

242. Zucchini S, Buzzi A, Barbieri M, Rodi D, Paradiso B, Binaschi A, Coffin JD, Marzola A, Cifelli P, Belluzzi O and Simonato M  (2009)  FGF-2 Overexpression Increases Excitability and Seizure Susceptibility but Decreases Seizure-Induced Cell Loss.  J. Neurosci., 28:13112-13124.

 

 

2007   LTP Program

241. Bartlett TE, Bannister NJ, Collett VJ, Dargan SL, Massey PV, Bortolotto ZA, Fitzjohn SM, Bashir ZI, Collingridge GL and Lodge D  (2007)  Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus.  Neuropharmacol., 52:60-70.

240. Colotta V, Catarzi D, Varano F, Capelli F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Pedata F, Schiesaro A, Morizzo E and Moro S  (2007)  New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A(3) adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.  J. Med. Chem., 50:4061-4074.

239. Cornejo BJ, Mesches MH, Coultrap S, Browning MD and Benke TA  (2007)  Single episode of neonatal seizures permanently alters glutamatergic synapses.  Ann. Neurol., 61:411-426.

238. Cunha-Reis D, Fontinha BM, Ribeiro JA and Sebastião AM  (2007)  Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus.  Neuropharmacol., 52:313-320.

237. Domenici MR, Scattoni ML, Martire A, Lastoria G, Potenza RL, Borioni A, Venerosi A, Calamandrei G and Popolia P  (2007)  Behavioral and electrophysiological effects of the adenosine A2A receptor antagonist SCH 58261 in R6/2 Huntington’s disease mice.  Neurobiology of Disease, 28:197–205.

236. Diogenes MJ, Assaife-Lopes N, Pinto-Duarte A, Ribeiro JA, Sebastiao AM  (2007)  Influence of age on BDNF modulation of hippocampal synaptic transmission: Interplay with adenosine A(2A) receptors.  Hippocampus, 17:577-585.

235. Frenguelli BG, Wigmore G, Llaudet E, Dale N  (2007)  Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus.  J. Neurochem., 101:1400-1413.

234. Guy J, Gan J, Selfridge J, Cobb S and Bird A  (2007)  Reversal of Neurological Defects in a Mouse Model of Rett Syndrome.  Science, 315: 1143-1147.

233.  Holman D, Feligioni M and Henley JM  (2007)  Differential redistribution of native AMPA receptor complexes following LTD induction in acute hippocampal slices.  Neuropharmacol., 52:92-99.

232. Humeau Y and Lüthi A  (2007)  Dendritic calcium spikes induce bi-directional synaptic plasticity in the lateral amygdala.  Neuropharmacol., 52:234-243.

231.  Huxter JR, Zinyuk LE, Roloff EVL, Clarke VRJ, Dolman NP, More JCA, Jane DE, Collingridge GL, and Muller RU  (2007)  Inhibition of kainate receptors reduces the frequency of hippocampal theta oscillations.  J. Neurosci., 27:2212–2223.

230. Kim J, Lee S, Park K, Hong I, Song B, Son G, Park H, Kim WR, Park E, Choe HK, Kim H, Lee C, Sun W, Kim K, Shin KS, Choi S  (2007)  Amygdala depotentiation and fear extinction.  PNAS, 104:20955-20960.

229. Kim MJ, Futai K, Jo J, Hayashi Y, Cho K and Sheng M  (2007)  Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95.  Neuron, 56:488–502.

228. Krüger K, Höing T, Bensch W, Diepgrond V, Ahnefeld M, Madeja M, Binding N and Musshoff U  (2007)  Effects of monomethyltin and dimethyltin compounds on heterologously expressed neuronal ion channels (Xenopus oocytes) and synaptic transmission (hippocampal slices).  NeuroToxicology, 28:114–125.

227. Kruger K, Repges H, Hippler J, Hartmann LM, Hirner AV, Straub H, Binding N and Musshoff U  (2007)  Effects of dimethylarsinic and dimethylarsinous acid on evoked synaptic potentials in hippocampal slices of young and adult rats.  Toxicol. App. Pharmacol., 225:40–46.

226. Le Magueresse C and Cherubini E  (2007)   Presynaptic calcium stores contribute to nicotine-elicited potentiation of evoked synaptic transmission at CA3-CA1 connections in the neonatal rat hippocampus.  Hippocampus, 17:316-325.

225. Li S, Feig LA and Hartley DM  (2007)  A brief, but repeated, swimming protocol is sufficient to overcome amyloid beta-protein inhibition of hippocampal long-term potentiation.  Eur. J. Neurosci., 26:1289-1298.

224. Maggi L, Sola E, Minneci F, Le Magueresse C, Changeux JP, and Cherubini E (2004)  Persistent decrease in synaptic efficacy induced by nicotine at Schaffer collateral–CA1 synapses in the immature rat hippocampus.  J Physiol., 559:863–874.

223. Maggio N and Segal M  (2007)  Unique Regulation of Long Term Potentiation in the Rat Ventral Hippocampus.  Hippocampus, 17:10-25.

222. Mallozzi C, Martire A, Domenici MR, Metere A, Popoli P, Di Stasi AMM  (2007)  L-NAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases.  J. Neurosci. Res., 85:2770-2777.

221. Martire A, Calamandrei G, Felici F, Scattoni ML, Lastoria G, Domenici MR, Tebano MT, Popoli P  (2007)  Opposite effects of the A2A receptor agonist CGS21680 in the striatum of Huntington’s disease versus wild-type mice.  Neurosci. Lett. 417:78–83.

220. McHugh, TJ, Jones MW, Quinn JJ, Balthasar N, Coppari R, Elmquist JK, Lowell BB, Fanselow MS, Wilson MA, Tonegawa S  (2007)  Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network.  Science, 317:94-9.

219. Nistico R, Piccirilli S, Sebastianelli L, Nistico G, Bernardi G, Mercuri  NB  (2007)  The blockade of k(+)-atp channels has neuroprotective effects in an in vitro model of brain ischemia.  Neuroinflammation in Neuronal Death and Repair International Review of Neurobiology, 82:383-395.

218.  Park H, Varadi A, Seok H, Jo J, Gilpin H, Liew CG, Jung S, Andrews PW, Molnar E, Cho K  (2007)  mGluR5 is involved in dendrite differentiation and excitatory synaptic transmission in NTERA2 human embryonic carcinoma cell-derived neurons.  Neuropharmacol., 52:1403-1414.

217. Pugliese AM, Coppi E, Volpini R, Cristalli G, Corradetti R, Jeong LS, Jacobson KA and Pedata F  (2007)  Role of adenosine A(3) receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration.  Biochem. Pharmacol., 74:768-779.

216. Queiroz CMT and Mello  (2007)  Synaptic plasticity of the CA3 commissural projection in epileptic rats: an in vivo electrophysiological study.   Eur. J. Neurosci., 25:3071-3079.

215. Sallert M, Malkki H, Segerstråle M, Taira T and Lauri SE  (2007)  Effects of the kainate receptor agonist ATPA on glutamatergic synaptic transmission and plasticity during early postnatal development.  Neuropharmacol., 52:1354-1365.

214. Tanaka K, Khiroug L, Santamaria F, Doi T, Ogasawara H, Ellis-Davies GCR, Kawato M, Augustine GJ  (2007)  Ca2+ requirements for cerebellar long-term synaptic depression: Role for a postsynaptic leaky integrator.  Neuron, 54:787-800.

213. Vickers CA and Wyllie DJA  (2007)  Late-phase, protein synthesis-dependent long-term potentiation in hippocampal CA1 pyramidal neurones with destabilized microtubule networks.  Brit. J. Pharmacol., 151:1071-1077.

212. Youssef FF, Hormuzdi SG, Irving AJ and Frenguelli BG  (2007)  Cannabinoid modulation of neuronal function after oxygen/glucose deprivation in area CA1 of the rat hippocampus.  Neuropharmacol., 52:1327-1335.

 

 

2006   LTP Program

211. Alakuijala A, Alakuijala J and Pasternack M  (2006)  Evidence for a functional role of GABAC receptors in the rat mature hippocampus.  Eur J. Neurosci., 23:514-520.

210. Ahmed Z, Wieraszko A  (2006)  Modulation of learning and hippocampal, neuronal plasticity by repetitive transcranial magnetic stimulation (rTMS). Bioelectromagnetics 27:288-294.

209. Coelho JE, Rebola N, Fragata I, Ribeiro JA, De Mendonca A and Cunha RA  (2006)  Hypoxia-induced desensitization and internalization of adenosine A(1) receptors in the rat hippocampus.  Neurosci., 138: 1195-1203.

208. Fragata IR, Ribeiro JA and Sebastião AM  (2006)  Nitric oxide mediates interactions between GABAA receptors and adenosine A1 receptors in the rat hippocampus.  Eur. J. Pharmacol., 543:32-39.

207. Jo J, Ball SM, Seok H, Oh SB, Massey PV, Molnar E, Bashir ZI, Cho K  (2006)  Experience-dependent modification of mechanisms of long-term depression.  Nature Neurosci., 9:170-172.

206. Kim HS, Jang HJ, Cho KH, Hahn SJ, Kim MJ, Yoon SH, Jo YH, Kim MS and Rhie D-J  (2006)  Serotonin inhibits the induction of NMDA receptor-dependent long-term potentiation in the rat primary visual cortex.  Brain Res., 1103:49-55.

205. Kruger K, Binding N, Straub H and Musshoff U  (2006)  Effects of arsenite on long-term potentiation in hippocampal slices from young and adult rats.  Toxicology Lett., 165:167-173.

204. Kuczewski N, Aztiria E and Domenici L  (2006)  Developmental modulation of synaptic transmission by acetylcholine in the primary visual cortex.  Brain Res., 1095:43-50.

203. Lanté F, de Jésus Ferreira, M-C, Guiramand J, Récasens M and Vignes M  (2006)  Low-frequency stimulation induces a new form of LTP, metabotropic glutamate (mGlu5) receptor- and PKA-dependent, in the CA1 area of the rat hippocampus.  Hippocampus, 16: 345-360.

202. Lauri SE, Vesikansa A, Segerstale M, Collingridge GL, Isaac JTR and Taira T  (2006)  Functional maturation of CA1 synapses involves activity-dependent loss of tonic kainate receptor-mediated inhibition of glutamate release.  Neuron, 50:415-429.

201. Li SM, Tian XJ, Hartley DM and Feig LA  (2006)  Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.  J. Neurosci., 26: 1721-1729.

200. Marrone MC, Marinelli S, Biamonte F, Keller F, Sgobio CA, Ammassari-Teule M, Bernardi G and Mercuri1 NB  (2006)  Altered cortico-striatal synaptic plasticity and related behavioural impairments in reeler mice.  Eur. J. Neurosci., 24:2061–2070.

199. Mlinar B, Mascalchi S, Mannaioni G, Morini R and Corradetti R  (2006)  5-HT4 receptor activation induces long-lasting EPSP-spike potentiation in CA1 pyramidal neurons.  Eur. J. Neurosci., 24:719-731.

198. Moult PR, Gladding CM, Sanderson TM, Fitzjohn SM, Bashir ZI, Molnar E and Collingridge GL  (2006)  Tyrosine phosphatases regulate AMPA receptor trafficking during metabotropic glutamate receptor-mediated long-term depression.  J. Neurosci., 26: 2544-2554.

197. Murakami N, Xie W, Lu RC, Chen-Hwang MC, Wieraszko A and Hwang YW  (2006)  Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome. J. Biol. Chem., 282:23712-23724.

196. Origlia N, Capsoni S, Domenici L and Cattaneo A  (2006)  Time window in cholinomimetic ability to rescue long-term potentiation in neurodegenerating anti-nerve growth factor mice.  J. Alzheimers Disease, 9:59-68.

195. Park Y, Jo J, Isaac JTR and Cho K  (2006)  Long-Term Depression of Kainate Receptor-Mediated Synaptic Transmission.  Neuron, 49:95-106.

194. Pavlov I, Rauvala H and Taira T  (2006)  Enhanced hippocampal GABAergic inhibition in mice overexpressing heparin-binding growth-associated molecule.  Neurosci., 139: 505-511.

193. Pearson T, Damian K, Lynas RE and Frenguelli BG  (2006)  Sustained elevation of extracellular adenosine and activation of A(1) receptors underlie the post-ischaemic inhibition of neuronal function in rat hippocampus in vitro.  J. Neurochem., 97:1357-1368.

192. Pintor A, Tebano MT, Martire A, Grieco R, Galluzzo M, Scattoni ML, Pèzzola A, Coccurello R, Felici F, Cuomo V, Piomelli D, Calamandrei G and Popoli P  (2006)  The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum.  Neuropharmacol., 51:1004-1012.

191. Pousinha PA, Diogenes MJ, Ribeiro JA and Sebastião AM  (2006)  Triggering of BDNF facilitatory action on neuromuscular transmission by adenosine A2A receptors.  Neurosci. Lett., 404:143-147.

190. Pugliese AM, Coppi E, Spalluto G, Corradetti R and Pedata F.  (2006)  A(3) adenosine receptor antagonists delay irreversible synaptic failure caused by oxygen and glucose deprivation in the rat CA1 hippocampus in vitro.  Br. J. Pharmacol., 147: 524-532.

189. Ragozzino D, Di Angelantonio S, Trettel F, Bertollini C, Maggi L, Gross C, Charo IF, Limatola C, and Eusebi F  (2006)  Chemokine Fractalkine/CX3CL1 Negatively Modulates Active Glutamatergic Synapses in Rat Hippocampal Neurons.  J. Neurosci., 26:10488–10498.

188. Ricci-Tersenghi F, Minneci F, Sola E, Cherubini E and Maggi L  (2006)  Multivesicular Release at Developing Schaffer Collateral–CA1 Synapses: An Analytic Approach to Describe Experimental Data.   J. Neurophysiol., 96:15–26.

187. Rosato-Siri M,  Cattaneo A and Cherubini E  (2006)  Nicotine-induced enhancement of synaptic plasticity at CA3–CA1 synapses requires GABAergic interneurons in adult anti-NGF mice.  J. Physiol., 576:361–377.

186. Sola E, Capsoni S, Rosato-Siri M, Cattaneo A and Cherubini E (2006)  Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer–collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice.  Eur. J. Neurosci., 24:1252–1264.

185. Siarey RJ, Kline-Burgess A, Cho M, Cho M, Balbo A, Best TK, Harashima C, Klann E and Galdzicki Z  (2006)  Altered signaling pathways underlying abnormal hippocampal synaptic plasticity in the Ts65Dn mouse model of Down syndrome.  J. Neurochem., 98:1266-1277.

184. Sim JA, Chaumont S, Jo J, Ulmann L, Young MT, Cho K, Buell G, North RA, and Rassendren F  (2006)  Altered Hippocampal Synaptic Potentiation in P2X4 Knock-Out Mice.  J. Neurosci., 26:9006-9009.

183. Sims RE and Hartell NA  (2006)  Differential susceptibility to synaptic plasticity reveals a functional specialization of ascending axon and parallel fiber synapses to cerebellar Purkinje cells.  J. Neurosci., 26:5153-5159.

182. Spalloni A, Geracitano E, Berretta N, Sgobio C, Bernardi G, Mercuri NB, Longone P and Ammassari-Teule M  (2006)  Molecular and synaptic changes in the hippocampus underlying superior spatial abilities in pre-symptomatic G93A+/+ mice overexpressing the human Cu/Zn superoxide dismutase (Gly93 → ALA) mutation.  Exp.  Neurol., 197:505-514.

181. Stoenica L, Senkov O, Gerardy-Schahn R, Weinhold B, Schachner M and Dityatev A  (2006)  In vivo synaptic plasticity in the dentate gyrus of mice deficient in the neural cell adhesion molecule NCAM or its polysialic acid.  Eur. J. Neurosci., 23:2255-2264.

180.  Tartar JL, King MA and Devine DP  (2006)  Glutamate-mediated neuroplasticity in a limbic input to the hypothalamus.  Stress, 9:13-19.

 

 

2005   LTP Program

179. Bortolotto ZA, Collett VJ, Conquet F, Jia Z, van der Putten H,  and Collingridge GL  (2005)  The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors.  Neuropharmacol., 49, Supplement 1, 13-25.

178. Cunha-Reis D, Ribeiro JA, Sebastiao AM  (2005)  VIP enhances synaptic transmission to hippocampal CA1 pyramidal cells through activation of both VPAC(1) and VPAC(2) receptors.  Brain Res., 1049:52-60.

177. Domenici MR, Potenza RL, Martire A, Coccurello R, Pezzola A, Reggio R, Tebano MT, Popoli P  (2005)  Chronic treatment with the mGlu5R antagonist MPEP reduces the functional effects of the mGlu5R agonist CHPG in the striatum of 6-hydroxydopamine-lesioned rats: Possible relevance to the effects of mGlu5R blockade in Parkinson's disease.  J. Neurosci. Res., 80:646-654.

176. Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, and Arber S  (2005)  A developmental switch in the response of DRG neurons to ETS transcription factor signaling.  PLOS Biology, 3:878-890.

175. Humeau Y, Herry C, Kemp N, Shaban H, Fourcaudot E, Bissière S, Lüthi A  (2005)  Dendritic Spine Heterogeneity Determines Afferent-Specific Hebbian Plasticity in the Amygdala.  Neuron, 45:119-131.

174. Kruger K, Diepgrond V, Ahnefeld M, Wackerbeck C, Madeja M, Binding N, Musshoff U  (2005)  Blockade of glutamatergic and GABAergic receptor channels by trimethyltin chloride.  Br. J. Pharmacol., 144: 283-292.

173. Kuczewski N, Aztiria E, Gautam D, Wess J, and Domenici L  (2005)  Acetylcholine modulates cortical synaptic transmission via different muscarinic receptors, as studied with receptor knockout mice.  J. Physiol., 566:907-919.

172. Lee HH, Choi SJ, Kim KJ, Cho HS, Kim SY and Sung KW (2005)  Dopamine Modulates Corticostriatal Synaptic Transmission through Both D1 and D2 Receptor Subtypes in Rat Brain.  Korean J. Physiol. Pharmacol., 9:263-268.

171. Lauri SE, Segerstrale M, Vesikansa A, Maingret F, Mulle C, Collingridge GL, Isaac JTR, and Taira T  (2005)  Endogenous activation of kainate receptors regulates glutamate release and network activity in the developing hippocampus.  J. Neurosci., 25:4473-4484.

170. Lim W, and Isaac JTR  (2005)  ATP hydrolysis is required for the rapid regulation of AMPA receptors during basal synaptic transmission and long-term synaptic plasticity.  Neuropharmacol., 48: 949-955.

169. Maingret F, Lauri SE, Taira T, and Isaac JTR  (2005)  Profound regulation of neonatal CA1 rat hippocampal GABAergic transmission by functionally distinct kainate receptor populations.  J. Physiol., 567:131-142.

168. Palmer CL, Lim W, Hastie PGR, Toward M, Korolchuk VI, Burbidge SA, Banting G, Collingridge GL, Isaac JTR,  and Henley JM  (2005)  Hippocalcin Functions as a Calcium Sensor in Hippocampal LTD.  Neuron, 47:487-494.

167. Raulo E, Tumova S, Pavlov I, Pekkanen M, Hienola A, Klankki E, Kalkkinen N, Taira T, Kilpelainen I, Rauvala H  (2005)  The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons. J. Biol. Chem., 280:41576-41583..

166. Rougier A, Arthaud S, Zombre N, and La Salle GL  (2005)  Patterns of dentate granule cell responses to perforant path stimulation in epileptic mice with granule cell dispersion.  Epilepsy Res., 63:119-129.

165. Siarey RJ, Villar AJ, Epstein CJ, and Galdzicki Z  (2005)  Abnormal synaptic plasticity in the Ts1Cje segmental trisomy 16 mouse model of Down syndrome.  Neuropharmacol., 49:122-128.

164. Sims RE, Hartell NA  (2005)  Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells.  J. Neurosci., 25: 3246-3257.

163. Tebano MT, Martire A, Rebola N, Pepponi R, Domenici MR, Gro MC, Schwarzschild MA, Chen JF, Cunha RA, Popoli P  (2005)  Adenosine A(2A) receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects.  J. Neurochem., 95:1188-1200.

162. Vickers CA, Dickson KS, Wyllie DJA  (2005)  Induction and maintenance of late-phase long-term potentiation in isolated dendrites of rat hippocampal CA1 pyramidal neurones.   J. Physiol. (London), 568:803-813.

161. Walsh DM, Townsend M, Podlisny MB, Shankar GM, Fadeeva JV, Agnaf OE, Hartley DM and Selkoe DJ  (2005)  Certain Inhibitors of Synthetic Amyloidß-Peptide (Aß) Fibrillogenesis Block Oligomerization of Natural Aß and Thereby Rescue Long-Term Potentiation.  J. Neurosci., 25:2455 - 2462.

160. Warburton EC, Glover CPJ, Massey PV, Wan HM, Johnson B, Bienemann A, Deuschle U, Kew JNC, Aggleton JP, Bashir ZI, Uney J, and Brown MW  (2005)  CAMP responsive element-binding protein phosphorylation is necessary for perirhinal long-term potentiation and recognition memory.  J. Neurosci., 25:6296-6303.

159. Wease KN, Davies SN  (2005)  Substance P selectively decreases paired pulse depression in the rat hippocampal slice.  BMC Neuroscience 6: Art. No. 66.

158. Wieraszko A, Ahmed Z, Armani J, Maqsood N, Philip S, Raja H  (2005)  Neurophysiological effects induced in the nervous tissue by low-frequency, pulsed magnetic fields. The Environmentalist, 25:145-155. *

 

 

2004   LTP Program

157. Brancucci A, Kuczewski N, Covaceuszach S, Cattaneo A, Domenici L  (2004)  NGF favors LTD over LTP in layer II-III neurons of rat visual cortex.  J. Physiol., 559:497-506.

156. Christensen JK, Paternain AV, Selak S, Ahring PK, Lerma J  (2004)  A mosaic of functional kainate receptors in hippocampal interneurons.  J. Neurosci., 24:8986-8993.

155. Clarke VRJ, Collingridge GL  (2004)  Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices.  Neuropharmacol., 47:363-372.

154. Cunha RA, Ribeiro JA, Malva JO  (2004)  Presynaptic kainate receptors modulating glutamatergic transmission in the rat hippocampus are inhibited by arachidonic acid.  Neurochem. International., 44:371-379.

153. Cunha-Reis D, Sebastiao AM, Wirkner K, Illes P, Ribeiro JA  (2004) VIP enhances both pre- and postsynaptic GABAergic transmission to hippocampal interneurones leading to increased excitatory synaptic transmission to CA1 pyramidal cells.  Br. J. Pharmacol., 143:733-744.

152. Diogenes MJ, Fernandes CC, Sebastiao AM and Ribeiro JA  (2004)  Activation of adenosine A2A receptor facilitates brain-derived neurotrophic factor modulation of synaptic atransmission in hippocampal slices.  J. Neurosci., 24:2905-2913.

151. El-Sherif Y, Witt-Enderby P, Li P-K, Tesoriero J, Hogan MV and Wieraszko A  (2004)  The actions of a charged melatonin receptor ligand, TMEPI, and an irreversible MT2 receptor agonist, BMNEP, on mouse hippocampal evoked potentials in vitro. Life Sci., 75:3147- 3156. *

150. Etherington LAV and Frenguelli BG  (2004)  Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner.  Eur.J. Neurosci., 19:2539-2550.

149. Gadalla AE, Pearson T, Currie AJ, Dale N, Hawley SA, Sheehan M, Hirst W, Michel AD, Randall A, Hardie DG, Frenguelli BG  (2004)  AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.  J. Neurochem., 88:1272-1282.

148.  Gassmann M, Shaban H, Vigot R, Sansig G, Haller C, Barbieri S, Humeau Y, Schuler V, Müller M, Kinzel B, Klebs K, Schmutz M, Froestl W, Heid J, Kelly PH, Gentry C, Jaton A-S, Van der Putten H, Mombereau C, Lecourtier L, Mosbacher J, Cryan JF, Fritschy J-M, Lüthi A, Kaupmann K, Bettler B  (2004)  Redistribution of GABAB(1) Protein and Atypical GABAB Responses in GABAB(2)-Deficient Mice.  J. Neurosci., 24:6086-6097.

147. Harris-Cerruti C, Kamsler A, Kaplan B, Lamb B, Segal M, Groner Y  (2004)  Functional and morphological alterations in compound transgenic mice overexpreszing Cu/Zn superoxide dismutaze and amyloid precursor protein.  Eur. J.  Neurosci., 19:1174-1190.

146. Kasyanov AM, Safilina VF,  Voronin LL, and Cherubini E  (2004)  GABA-mediated giant depolarizing potentials as coincidence detectors for enhancing synaptic efficacy in the developing hippocampus.  PNAS, 101:3967-3972.

145. Koponen E, Voikar V, Riekki R, Saarelainen T, Rauramaa T, Rauvala H, Taira T and Castren E  (2004)  Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLC gamma pathway, reduced anxiety, and facilitated learning.  Mol. Cell. Neurosci. 26:166-181.

144. Luthi A, Wikstrom MA, Palmer MJ, Matthews P, Benke TA, Isaac JTR, Collingridge GL  (2004)  Bi-directional modulation of AMPA receptor unitary conductance by synaptic activity. BMC Nuerosci. 5: art. no. 44.

143. Massey PV, Johnson BE, Moult PR, Auberson YP, Brown MW, Molnar E, Collingridge GL, Bashir ZI  (2004)  Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.  J. Neurosci., 24:7821-7828.

142. Middei S, Geracitano R, Caprioli A, Mercuri N, Ammassari-Teule M  (2004)  Preserved Fronto-Striatal Plasticity and Enhanced Procedural Learning in a Transgenic Mouse Model of Alzheimer's Disease Overexpressing Mutant hAPPswe.  Learn. Mem., 11:447-452.

141. More JCA, Nistico R, Dolman NP, Clarke VRJ, Alt AJ, Ogden AM, Buelens FP, Troop HM, Kelland EE, Pilato F, Bleakman D, Bortolotto ZA, Collingridge GL, Jane DE  (2004)  Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist.  Neuropharmacol., 47:46-64.

140. Palmer MJ, Isaac JTR, Collingridge GL  (2004)  Multiple, developmentally regulated expression mechanisms of long-term potentiation at CA1 synapses.  J. Neurosci., 24:4903-4911.

139. Pavlov I, Riekki R, Taira T  (2004)  Synergistic action of GABA-A and NMDA receptors in the induction of long-term depression in glutamatergic synapses in the newborn rat hippocampus.  Eur. J. Neurosci., 20: 3019-3026..

138. Pearson T, Frenguelli BG  (2004)  Adrenoceptor subtype-specific acceleration of the hypoxic depression of excitatory synaptic transmission in area CA1 of the rat hippocampus.  Eur. J. Neurosci., 20:1555-1565.

137. Terashima A, Cotton L, Dev KK, Meyer G, Zaman S, Duprat F, Henley JM, Collingridge GL, Isaac JTR  (2004)  Regulation of Synaptic Strength and AMPA Receptor Subunit Composition by PICK1.  J. Neurosci., 24:5381-5390.

136. Thuault SJ, Brown JT, Sheardown SA, Jourdain S, Fairfax B, Spencer JP, Restituito S, Nation JHL, Topps S, Medhurst AD, Randall AD, Couve A, Moss SJ, Collingridge GL, Pangalos MN, Davies CH, Calver AR  (2004)  The GABAB2 subunit is critical for the trafficking and function of native GABAB receptors.  Biochem. Pharmacol.,  68:1655-1666.

135. Voronin LL, Altinbaev RS, Bayazitov IT, Gasparini S, Kasyanov AV, Saviane C, Savtchenko L and Cherubini E  (2004)  Postsynaptic depolarisation enhances transmitter release and causes the appearance of responses at "silent" synapses in rat hippocampus.  Neuroscience, 126:45-59.

134. Wan H, Warburton EC, Zhu XO, Koder TJ, Park Y, Aggleton JP, Cho K, Bashir ZI, Brown MW  (2004)  Benzodiazepine impairment of perirhinal cortical plasticity and recognition memory.  Eur. J. Neurosci., 20: 2214-2224.

133. Wieraszko A  (2004)  Amplification of evoked potentials recorded from mouse hippocampal slices by very low repetition rate pulsed magnetic fields. Bioelectromagnetics, 25:537-544. *

 

 

2003   LTP Program

132. Almeida CG, de Mendonca A, Cunha RA, Ribeiro JA  (2003)  Adenosine promotes neuronal recovery from reactive oxygen species induced lesion in rat hippocampal slices. Neurosci. Lett., 339:127-130.

131. Bissiere S, Humeau Y, Luthi A  (2003)  Dopamine gates LTP induction in lateral amygdala by suppressing feedforward inhibition.  Nature Neurosci., 6:587-592.

130. Brown TM, Brotchie JM and Fitzjohn SM  (2003)  Cannabinoids decrease corticostriatal synaptic transmission vie an effect on glutamate uptake.  J. Neurosci., 23:11073-11077.

129. Choi SJ, Chung WS, Kim K-J and Sung K-W  (2003)  Inhibitory modulation of 5-hydroxytryptamine on corticostriatal synaptic transmission in rat brain slice.  Korean J. Physiol. Pharmacol., 7:295-301.

128. Curtis J, Errington M, Biss T, Voss K, MacLeod N  (2003)  Age-dependent loss of PTP and LTP in the hippocampus of PrP-null mice.  Neurobiol. Disease, 13 55-62.

127. El-Sherif Y, Tesoriero J, Hogan MV and Wieraszko A  (2003)  Melatonin regulates neuronal plasticity in hippocampus. J. Neurosci. Res., 72:454-460. *

126. Frenguelli BG, Llaudet E, and Dale N  (2003)  High-resolution real-time recording with microelectrode biosensors reveals novel aspects of adenosine release during hypoxia in rat hippocampal slices.  J. Neurochem., 86:1506-1515.

125. Galvan CD, Wenzel JH, Dineley KT, Lam TT, Schwartzkroin PA, Sweatt JD, Swann JW  (2003)  Postsynaptic contributions to hippocampal network hyperexcitability induced by chronic activity blockade in vivo.  Eur. J. . Neurosci, 18:1861-1872.

124. Gemperle AY, Enz A, Pozza MF, Luthi A, Olpe HR  (2003)  Efects of clozapine, haloperidol and iloperidone on neurotransmission and synaptic plasticity in prefrontal cortex and their accumulation in brain tissue: An in vitro study.  Neuroscience, 117:681-695.

123. Geracitano R, Paolucci E, Prisco S, Guatteo E, Zona C, Longone P, Ammassari-Teule M, Bernardi G, Berretta N, Mercuri NB  (2003)  Altered long-term corticostriatal synaptic plasticity in transgenic mice overexpressing human CU/ZN superoxide dismutase (GLY93 ALA) mutation.  Neuroscience,  118:399-408.

122. Hayes DM, Braud S, Hurtado DE, McCallum J, Standley S, Isaac JTR and Roche KW  (2003)  Trafficking and surface expression of the glutamate receptor subunit, KA2.  Biochem.  Biophys. Res. Comm., 310:8-13.

121. Hirbec H, Francis JC, Lauri SE, Braithwaitwe SP, Coussen F, Mulle C, Dev KK, Couthino V, Meyer G, Isaac JTR, Collingridge GL and Henley JM  (2003)  Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre Synapses by PICK1 and GRIP.  Neuron, 37: 625-638.

120. Humeau Y, Shaban H, Bissière S and Lüthi A  (2003)  Presynaptic induction of heterosynaptic associative plasticity in the mammalian brain.  Nature, 426:841-845.

119. Lauri SE, Bortolotto ZA, Nistico R, Bleakman D, Ornstein PL, Lodge D, Isaac JTR, Collingridge GL  (2003)  A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus.  Neuron 39:327-341.

118. Lopes LV, Rebola N, Costenla AR, Halldner L, Jacobson MA, Oliveira CR, Richardson PJ, Fredholm BB, Ribeiro JA, Cunha RA  (2003)  Adenosine A(3) receptors in the rat hippocampus: Lack of interaction with A(1) receptors.  Drug Dev. Res., 58:428-438.

117. Kamsler A, Segal M  (2003)  Paradoxical actions of hydrogen peroxide on long-term potentiation in transgenic superoxide dismutase-1 mic.  J. Neurosci. 23:10359-10367.

116. Kamsler A, Segal M  (2003)  Hydrogen peroxide modulation of synaptic plasticity.  J. Neurosci. 23:269-276.

115. Massey PV, Warburton EC, Wynick D, Brown MW and Bashir ZI  (2003)  Galanin regulates spatial memory but not visual recognition memory or synaptic plasticity in perirhinal cortex.  Neuropharmacol., 44: 40-48.

114. Maggi L, Le Magueresse C, Changeux JP, and Cherubini E  (2003)  Nicotine activates immature "silent" connections in the developing hippocampus.  PNAS, 100:2059-2064.

113. Pybus R, Barnard E, Estibeiro P, Mullins J and MacLeod N  (2003)  Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related.  Neurobiol. Disease, 12:212-224.

112. Rammes G, Palmer M, Eder M, Dodt HU, Zieglgansberger W, Collingridge GL  (2003)  Activation of mGlu receptors induces LTD without affecting postsynaptic sensitivity of CA1 neurons in rat hippocampal slices.  J. Physiol. 546:455-460.

111. Rebola N, Coelho JE, Costenla AR, Lopes LV, Parada A, Oliveira CR, Soares-da-Silva P, de Mendonca A, Cunha RA  (2003)  Decrease of adenosine A(1) receptor density and of adenosine neuromodulation in the hippocampus of kindled rats.  Eur J. Neurosci. 18:820-828..

110. Rebola N, Sebastiao AM, de Mendonca A, Oliveira CR, Ribeiro JA, Cunha RA  (2003)  Enhanced adenosine A(2A) receptor facilitation of synaptic transmission in the hippocampus of aged rats.  J. Neurophysiol., 90: 1295-1303.

109. Ross FM, Allan SM, Rothwell NJ and Verkhratsky A  (2003)  A dual role for interleukin-1 in LTP in mouse hippocampal slices.  J. Neuroimmunol., 144:61-67.

108. Warburton EC, Koder T, Cho K, Massey PV, Duguid G, Barker GRI, Aggleton JP, Bashir ZI, Brown MW  (2003)  Cholinergic neurotransmission is essential for perirhinal cortical plasticity and recognition memory.  Neuron 38:987-996.

107. Wikström MA, Matthews P, Roberts D, Collingridge GL and Bortolotto ZA  (2003)  Parallel kinase cascades are involved in the induction of LTP at hippocampal CA1 synapses, Neuropharmacol., 45:828-836.

 

 

2002   LTP Program

106. Cho K, Brown MW, Bashir ZI  (2002)  Mechanisms and physiological role of enhancement of mGlu5 receptor function by group II mGlu receptor activation in rat perirhinal cortex.  J. Physiol. 540:895-906.

105. Clarke VRJ, Collingridge GL  (2002)  Characterisation of the effects of ATPA, a GLU(K5) receptor selective agonist, on excitatory synaptic transmission in area CA1 of rat hippocampal slice.  Neuropharmacol. 42:889-902.

104. Daw MI, Bortolotto ZA, Saulle E, Zaman S, Collingridge GL, Isaac JTR  (2002)  Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression.  Nature Neurosci., 5:835-836.

103. Garden DLF, Kemp N, Bashir ZI  (2002)  Differences in GABAergic transmission between two inputs into the perirhinal cortex. Eur. J. Neurosci., 16:437-444.

102. Kidd FL, Coumis U, Collingridge GL, Crabtree JW, Isaac JTR  (2002)  A presynaptic kainate receptor is involved in regulating the dynamic properties of thalamocortical synapses during development.  Neuron 34:635-646.

101. Morton RA, Kuenzi FM, Fitzjohn SM, Fitzjohn SM, Rosahl TW, Smith D, Zheng H, Shearman M, Collingridge GL and Seabrook GR  (2002)  Impairment in hippocampal long-term potentiation in mice underexpressing the Alzheimer's disease related gene presenilin-1.  Neurosci. Lett. 319:37-40.

100. Moult PR, Schnabel R, Kilpatrick IC, Bashir ZI, Collingridge GL  (2002)  Tyrosine dephosphorylation underlies DHPG-induced LTD.  Neuropharmacol. 43:175-180.

99. Smolders I, Bortolotto ZA, Clarke VRJ, Warre R, Khan GM, O'Neill MJ, Ornstein PL, Bleakman D, Ogden A, Weiss B, Stables JP, Ho KH, Ebinger G, Collingridge GL, Lodge D, Michotte Y  (2002)  Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures.  Nature Neurosci., 5:796-804.

98. Al-Hayani A and Davies SN  (2002)  Effect of cannabinoids on synaptic transmission in the rat hippocampal slice is temperature dependent.  Eur. J. Pharmacol., 442:47-54.

97. Cunha RA, Coelho JE, Costenla AR, Lopes LV, Parada A, de Mendonca A, Sebastiao AM, Ribeiro JA  (2002)  Effects of carbamazepine and novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives on synaptic transmission in rat hippocampal slices.  Pharmacol. Toxicol. 90:208-213.

96. Kaksonen M, Pavlov I, Voikar V, Lauri SE, Hienola A, Riekki R, Lakso M, Taira T, Rauvala H  (2002)  Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory.  Mol. Cell Neurosci. 21:158-172.

95. Lopes LV, Cunha RA, Kull B, Fredholm BB and Ribeiro JA  (2002)  Adenosine A(2A) receptor facilitation of hippocampal synaptic transmission is dependent on tonic A(1) receptor inhibition.  Neuroscience, 112:319-329.

94. Maffei A, Prestori F, Rossi P, Taglietti V and D'Angelo E  (2002)  Presynaptic current changes at the mossy fiber - granule cell synapse of cerebellum during LTP.  J. Neurophysiol., 88:627-638..

93. Pavlov I, Voikar V, Kasonen M, Lauri SE, Hienola A, Taira T, Rauvala H  (2002)  Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice.  Mol. Cell. Neurosci. 20: 330-342.

92. Pesavento E, Capsoni S, Domenici L, Cattaneo A  (2002)  Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti-nerve-growth-factor mice.  Eur. J. Neurosci., 15:1030-1036.

91.Ragozzino D, Renzi M, Giovannelli A and Eusebi F  (2002)  Stimulation of chemokine CXC receptor 4 induces synaptic depression of evoked parallel fibers inputs onto Purkinje neurons in mouse cerebellum.  J. Neuroimmunol., 127:30-36..

 

 

2001   LTP Program

90. Amet LEA, Lauri SE, Hienola A, Croll SD, Lu Y, Levorse JM, Prabhakaran B, Taira T, Rauvala H and Vogt TF  (2001)  Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule.  Mol. Cell Neurosci., 17:1014-1024.

89. Buckby LE and Lacey MG  (2001)  Depression of excitatory cortico-nucleus accumbens synaptic transmission in rat brain slices by dopamine, but not adenosine, depends upon intracortical mechanisms.  Exp. Brain Res., 141:560-566.

88. Buckby LE and Lacey MG  (2001)  Epileptiform activity in the nucleus accumbens induced by GABAA receptor antagonists in rat forebrain slices is of cortical origin.  Exp. Brain Res., 141:146-152.

87. Bukalo O, Schachner M and Dityatev A  (2001)  Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of Tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus.  Neuroscience, 104:359-369.

86. Cho K, Aggleton JP, Brown MW and Bashir ZI (2001)  An experimental test of predictions concerning the role of calcium in determining synaptic strength.  J. Physiol (London), 532:459-466.

85. Fitzjohn SM, Morton RA, Kuenzi F, Rosahl TW, Shearman M, Lewis H, Smith D, Reynolds DS, Davies CH, Collingridge GL and Seabrook GR   (2001)  Age-related impairment of synaptic transmission but normal long-term potentiation in transgenic mice that over-express the human APP695SWE mutant form of amyloid precursor protein.  J. Neurosci, 21:4691-4698.

84. Fitzjohn SM, Palmer MJ, May JER, Neeson A, Morris SAC and Collingridge GL (2001)  A characterisation of long-term depression induced by metabotropic glutamate receptor activation in the rat hippocampus in vitro.  J Physiol (Lond), 537: 421-430.

83. Fitzjohn SM, Pickard L, Duckworth JK, Molnar E, Henley JM, Collingridge GL and Noel J   (2001)  An electrophysiological characterization of long-term potentiation in cultured dissociated hippocampal neurones.  Neuropharmacol., 41:693-699.

82. Jacoby S, Sims RE and Hartell NA  (2001)  Nitric oxide is required for the induction and heterosynaptic spread of long-term potentiation in rat cerebellar slices.  J. Physiol., 535:825-839

81. Kalikulov D, Ayar A, Nuritova F, Frenguelli BG, McClelland D, Martin DJ, Davidson I and Scott RH  (2001). Venom from Anemesia species of spider modulates high voltage-activated Ca2+ currents from rat cultured sensory neurones and excitatory postsynaptic currents from rat hippocampal slices. Cell Calcium 30:212-221.

80. Kim H-S, Kim H-S, Hahn SJ, Kim M-J, Yoon SH, Jo Y-H, Kim M-S and Rhie D-J  (2005)  Effects of fluoxetine on the induction of long-term potentiation in rat frontal cortex.  Korean J. Physiol Pharmacol., 8:295-300.

79. Lauri SE, Bortolotto ZA, Bleakman D, Ornstein PL, Lodge D, Isaac JTR and Collingridge GL  (2001)  A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP.  Neuron, 32:697-709.

78. Lauri SE, Delany C, Clarke VRJ, Bortolotto ZA, Ornstein PL, Isaac JTR and Collingridge GL  (2001)  Synaptic activation of a presynaptic kainate receptor facilitates AMPA receptor-mediated synaptic transmission at hippocampal mossy fibre synapses.  Neuropharmacology 41: 907-915.

77. Kidd FL and Isaac JTR  (2001)  Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: Role of glutamate clearance.  J Neurophysiol. 86:1139-1148.

76. Massey PV, Bhabra G, Cho K, Brown MW, Bashir ZI  (2001)  Activation of muscarinic receptors induces protein synthesis-dependent long-lasting depression in the perirhinal cortex.  Eur. J. Neurosci., 14:145-152.

75. Pearson T, Nuritova F, Caldwell D, Dale N and Frenguelli BG  (2001)  A depletable pool of adenosine in area CA1 of the rat hippocampus.  J. Neurosci., 21:2298-2307.

74. Schnabel R, Kilpatrick IC and Collingridge GL  (2001)  Protein phosphatase inhibitors facilitate DHPG-induced LTD in the CA1 region of the hippocampus.  Br. J. Pharmacol., 132:1095-1101.

73. Sebastiao AM, de Mondonca A, Moreira T and Ribeiro JA (2001)  Activation of synaptic NMDA receptors by action potential-dependent release of transmitter during hypoxia impairs recovery of synaptic transmission on reoxygenation.   J. Neurosci., 21:8564-8571.

72. Tang J, Wotjak CT, Wagner S, Williams G, Schachner M and Dityatev A  (2001)  Potentiated amygdaloid auditory-evoked potentials and freezing behavior after fear conditioning in mice. Brain Res., 919:232-241.

 

 

2000   LTP Program

71. Al-Hayani A and Davies SN  (2000)  Cannabinoid receptor mediated inhibition of excitatory synaptic transmission in the rat hippocampal slice is developmentally regulated.  Br. J. Pharmacol., 131:663-665.

70. Berretta N, Rossokhin AV, Kasyanov AM, Sokolov MV, Cherubini E and Voronin LL  (2000)  Postsynaptic hyperpolarization increases the strength of AMPA-mediated synaptic transmission at large synapses between mossy fibers and CA3 pyramidal cells.  Neuropharmacol., 39:2288-2301.

69. Bortolotto ZA and Collingridge GL (2000)  A role for protein kinase C in a form of metaplasticity that regulates the induction of long-term potentiation at CA1 synapses of the adult rat hippocampus.  Eur. J. Neurosci., 12:4055-4062.

68. Cho K, Kemp N, Noel J, Aggleton JP, Brown MW and Bashir ZI (2000)  A new form of long-term depression in the perirhinal cortex.  Nature Neurosci.,  3:150-156.

67. Coelho JE, de Mendonca A and Ribeiro JA  (2000)  Presynaptic inhibitory receptors mediate the depression of synaptic transmission upon hypoxia in rat hippocampal slices.  Brain Res., 869:158-165.

66. Cunha RA, Almeida T and Ribeiro JA  (2000)  Modification by aracidonic acid of extracellular adenosine metabolism and neuromodulatory action in the rat hippocampus.  J. Biol. Chem., 275:37572-37581.

65. Cunha RA and Ribeiro JA  (2000)  Adenosine A(2A) receptor facilitation of synaptic transmission in the CA1 area of the rat hippocampus requires protein kinase C but not protein kinase A activation.  Neurosci. Lett., 289:127-130.

64. Dale N, Pearson T and Frenguelli BG  (2000)  Direct measurement of adenosine release during hypoxia in the CA1 region of the rat hippocampal slice.  J. Physiol. (Lond.), 526:143-155.

63. Daw MI, Chittajallu R, Bortolotto ZA, Dev KK, Duprat F, Henley JH, Collingridge GL and Isaac JTR  (2000)  PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses.  Neuron, 28:873-886.

62. Doherty AJ, Palmer MJ, Bortolotto ZA, Hargreaves A, Kingston AE, Ornstein PL, Schoepp DD, Lodge D and Collingridge GL  (2000)  A novel, competitive mGlu5 receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices.  Br. J. Pharmacol., 131:239-244.

61. Eckhardt M, Bukalo O, Chazal G, Wang L, Goridis C, Schachner M, Gerardy-Schahn R, Cremer H and Dityatev A (2000)  Mice Deficient in the polysialyltransferase ST8SialV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity.  J. Neurosci., 20:5234-5244.

60. Fitzjohn SM, Morton RA, Kuenzi F, Davies CH, Searbook GR and Collingridge GL  (2000)  Similar levels of long-term potentiation in amyloid precursor protein-null and wild-type mice in the CA1 region of picrotoxin treated slice.  Neurosci Lett., 288:9-12.

59. Frankiewcz T, Pilc A and Parsons CG  (2000)  Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices.  Neuropharmacol., 39:631-642.

58. Kasyanov AM, Maximov VV, Byzov AL, Berretta N, Sokolov MV, Gasparini S, Cherubini E, Reymann KG and Voronin LL (2000)  Differences in amplitude-voltage relations between minimal and composite mossy fibre responses of rat CA3 hippocampal neurons support the existence of intrasynaptic ephaptic feedback in large synapses.  Neurosci.  101:323-336. .

57. Kemp N, McQueen J, Faulkes S and Bashir ZI  (2000)  Different forms of LTD in the CA1 region of the hippocampus: role of age and stimulus protocol.  Eur. J. Neurosci., 12:360-366.

56. Kidd FL and Isaac JTR  (2000)  Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.  Neuropharmacol., 39:725-732.

55. Lauri SE, Taira T and Rauvala H  (2000)  High-frequency synaptic stimulation induces association of fyn and c-src to distinct phosphorylated components.  Neuroreport, 11:997-1000.

54.  Miyata M, Finch EA, Khiroug L, Hashimoto K, Hayasaka S, Oda SI, Inouye M, Yakagishi Y, Augustine GJ and Kano M (2000)  Local calcium release in dendritic spines required form long-term synaptic depression.  Neuron, 28:233-244.

53.  Pesavento E, Margotti E, Righi M, Cattaneo A and Domenici L  (2000)  Blocking the NGF-TrkA interaction rescues the developmental loss of LTP in the rat visual cortex: Role of the cholinergic system.  Neuron, 25:165-175.

52.  Pearson T and Frenguelli BG  (2000)  Volume-regulated anion channels do not contribute extracellular adenosine during the hypoxic depression of excitatory synaptic transmission in area CA1 of rat hippocampus.  Eur. J. Neurosci., 12:3064-3066.

51.Ribar TJ, Rodriguiz RM, Khiroug L, Wetsel WC, Augustine GJ and Means AR  (2000)  Cerebellar defects in Ca2+/Calmodulin kinase IV-deficient mice. J. Neurosci. 20:RC107(1-5).

50. Ross FM, Cassidy J, Wilson M, and Davies SN (2000) Developmental regulation of hippocampal excitatory synaptic transmission by metabotropic glutamate receptors. Br. J. Pharmacol., 131:453-464.

49. Ross FM, Gwyn P, Spanswick D and Davies SN (2000)  Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices.  Neuroscience, 100:789-796.

48. Sebastiao AM, Macedo MP and Riveiro JA  (2000)  Tonic activation of A2A adenosine receptors unmasks, and of A1 receptors prevents, a facilitatory action of calcitonin gene-related peptide in the rat hippocampus.  Br. J. Pharmacol., 129:374-380.

47. Sebastiao AM, Cunha RA, de Mendonca A and Riveiro JA  (2000)  Modification of adenosine modulation of synaptic transmission in the hippocampus of aged rats.  Br. J. Pharmacol., 131:1629-1634.

46. Sermasi E, Margotti E, Cattaneo A and Domenici L  (2000)  Trk B signalling controls LTP but not LTD expression in the developing rat visual cortex.  Eur. J. Neurosci., 12:1411-1419.

45. Tolchard S, Clarke G, Collingridge GL and Fitzjohn SM  (2000)  Modulation of synaptic transmission in the rat ventral septal area by the pharmacological activation of metabotropic glutamate receptors.  Eur. J. Neurosci., 12:1843-1847.

44. Wang SS, Khiroug L and Augustine GJ. Quantification of spread of cerebellar long-term depression with chemical two-photon uncaging of glutamate. Proc. Natl. Acad. Sci. 97:8635-8640.

43. Ziakopoulos Z, Brown MW and Bashir ZI  (2000)  GABAB receptors mediate frequency-dependent depression of excitatory potentials in rat perirhinal cortex in vitro.  Eur. J. Neurosci., 12:803-809.

 

 

1999   LTP Program

42. Berretta N, Rossokhin AV, Cherubini E, Astrelin AV and Voronin LL (1999) Long-term synaptic changes induced by intracellular tetanization of CA3 pyramidal neurons in hippocampal slices from juvenile rats. Neuroscience, 93:469-477.

41. Bortolotto ZA, Clarke VRJ, Delany CM, Parry MC, Vignes M, Hoo KH, Miu P, Brinton B, Fantaske R, Ogden A, Gates M, Ornstein PL, Lodge D, Bleakman D and Collingridge GL (1999) Kainate receptors are involved in synaptic plasticity. Nature, 402:297-301.

40. Bortolotto ZA and Collingridge GL (1999) Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CAI synapses in the hippocampus. Biochem. Soc. Trans., 27:170-174.

39. Fitzjohn SM, Kingston AE, Lodge D and Collingridge GL (1999) DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterization and sensitivity to novel mGlu receptor antagonists. Neuropharmacol., 38:1577-1583.

38. Frankiewcz T and Parsons CG  (1999)  Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices.  Neuropharmacol., 38:1253-1259.

37. Kemp N and Bashir ZI (1999) Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors. Neuropharmacol., 38:495-504.

36. Kidd FL and Isaac JTR (1999) Developmental and activity-dependent regulation of kainate receptors at thalamocortical synapses. Nature, 400:569-573.

35. Luthi A, Chittajallu R, Duprat F, Palmer MJ, Benke TA, Kidd FL, Henley JM, Isaac JTR and Collingridge GL (1999) Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF GluR2 interaction. Neuron, 24:389-399.

34. McCaffery B, Cho D, Bortolotto ZA, Aggleton JP, Brown MW, Conquet F, Collingridge GL and Bashir ZI (1999) Synaptic depression induced by pharmacological activation of metabotropic glutamate receptors in the perirhinal cortex in vitro. Neuroscience, 93:977-984.

33. Parsons CG, Danysz W, Bartmann A, Spielmanns P, Frankiewicz T, Hesselink M, Eilbacher B and Quack G  (1999)  Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo.  Neuropharmacol., 38:85-108.

32. Schnabel R, Kilpatrick IC and Collingridge GL  (1999)  An investigation into signal transduction mechanisms involved in DHPG-induced LTD in the CA1 region of the hippocampus.  Neuropharmacol.,  38:1585-1596.

31. Schnabel R, Palmer MJ, Kilpatrick IC and Collingridge GL  (1999)  A CaMKII inhibitor, KN-62, facilitates DHPG-induced LTD in the CA1 region of the hippocampus. Neuropharmacol., 38:605-608.

30. Sermasi E, Tropea D. and Domenici L  (1999)  Long term depression is expressed during postnatal development in rat visual cortex: a role for visual experience.  Dev. Brain Res., 113:61-65.

29. Siarey RJ, Carlson EJ, Epstein CJ, Balbo A, Rapoport SI and Galdzicki Z (1999) Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. Neuropharmacol., 38:1917-1920..

28. Ziakopoulos Z, Tillett CW, Brown MW and Bashir ZI  (1999)  Input- and layer-dependent synaptic plasticity in the rat perirhinal cortex in vitro. Neuroscience, 92:459-472.

 

 

1998   LTP Program

27. Avignone E, Molnar M, Berretta N, Casamenti F, Prosperi C, Ruberti F, Cattaneo A and Cherubini E  (1998)  Cholinergic function in the hippocampus of juvenile rats chronically deprived of NGF. Dev. Brain Res., 109:137-147.

26. Berretta N. and Cherubini E. (1998) A novel form of long-term depression in the CA1 area of the adult rat hippocampus independent of glutamate receptors activation. Eur. J. Neurosci., 10:2957-2963.

25. Benke TA, Luthi A, Isaac JTR and Collingridge GL (1998) Modulation of AMPA receptor unitary conductance by synaptic activity. Nature, 393:793-797.

24. Bortolotto ZA and Collingridge GL (1998) Involvement of calcium/calmodulin-dependent protein kinases in the setting of a molecular switch involved in hippocampal LTP. Neuropharmacol., 37:535-544.

23. Crabtree JW, Collingridge GL and Isaac JTR (1998) A new intrathalamic pathway linking modality-related nuclei in the dorsal thalamus. Nature Neurosci., 1:389-394.

22. Domenici MR, Berretta N and Cherubini E (1998) Two distinct forms of long-term depression coexist at the mossy fiber-CA3 synapse in the hippocampus during development. PNAS, 95:8310-8315.

21. Fitzjohn SM, Bortolotto ZA, Palmer MJ, Doherty MJ, Doherty AJ, Ornstein PL, Schoepp DD, Kingston AE, Lodge D and Collingridge GL (1998) The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity. Neuropharmacol., 37:1445-1458.

20. Isaac JTR, Luthi A, Palmer MJ, Anderson WW, Benke TA and Collingridge GL (1998) An investigation of the expression mechanism of LTP of AMPA receptor- mediated synaptic transmission at hippocampal CA1 synapses using failures analysis and dendritic recordings. Neuropharmacol., 37:1399-1410.

19. Johnston AJ, Fraser JR, Jeffrey M and MacLeod NK (1998) Synaptic plasticity in the CA1 area of the hippocampus of scrapie-infected mice. Neurobiol. Disease, 5:188-195.

18. Nishimune A, Isaac JTR, Molnar E, Noel J, Nash SR, Tagaya M, Collingridge GL, Nakanishi S and Henley JM (1998) NSF binding to GluR2 regulates synaptic transmission. Neuron, 21:87-97.

17. Ruberti F, Berretta N, Cattaneo A and Cherubini E (1997) NGF antibodies impair LTD in the mossy fibre-CA3 synapse in the developing hippocampus. Dev. Brain Res., 101: 295-297.

16. Paton GS, Pertwee RG and Davies SN (1998) Correlation between cannabinoid mediated effects on paired pulse depression and induction of long term potentiation in the rat hippocampal slice. Neuropharm., 37:1123-1130.

15. Vignes M, Clarke VRJ, Parry MJ, Bleakman D, Lodge D, Ornstein PL and Collingridge GL (1998) The GluR5 subtype of kainate receptor regulates excitatory synaptic transmission in areas CA1 and CA3 of the rat hippocampus. Neuropharmacol., 37:1269-1277.

 

 

1997   LTP Program

14. Doherty AJ, Palmer MJ, Henley JM, Collingridge GL and Jane DE (1997)  (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu(5), but not mGlu(1), receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus.  Neuropharmacol., 36:265-267.

13. Harvey J, Palmer MJ, Irving AJ, Clarke VRJ. and Collingridge GL (1996)  NMDA receptor dependence of mGlu-mediated depression of synaptic transmission in the CA1 region of the rat hippocampus. Br. J. Pharmacol., 119:1239-1247.

12. Kemp N and Bashir ZI (1997) A role for adenosine in the regulation of long-term depression in the adult rat hippocampus in vitro. Neurosci. Lett., 225:189-192.

11. Kemp N and Bashir ZI (1997) NMDA receptor-dependent and –independent long-term depression in the CA1 region of the adult rat hippocampus in vitro. Neuropharmacol., 36:397-399.

10. Palmer MJ, Irving AJ, Seabrook GR, Jane DE and Collingridge GL (1997) The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus. Neuropharmacol., 36:1517-1532.

9. Siarey RJ, Stoll J, Rapoport SI and Galdzicki Z (1997) Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down Syndrome. Neuropharmacol., 36:1549-1554.

8. Vignes M, Bleakman D, Lodge D and Collingridge GL (1997) The synaptic activation of the GluR5 subtype of kainate receptor in area CA3 of the rat hippocampus. Neuropharmacol., 36:1477-1481. 

7. Vignes M and Collingridge GL (1997) The synaptic activation of kainate receptors. Nature, 388:179-182.

 

 

1996   LTP Program

6. Bresink I, Benke TA, Collett VJ, Seal AJ, Parsons CG, Henley JM and Collingridge GL (1996) Effects of memantine on recombinant rat NMDA receptors expressed in HEK 293 cells. Br. J. Pharmacol., 119:195-204.

5. Bushell TJ, Jane DE, Tse HW, Watkins JC, Garthwaite J and Collingridge GL (1996)  Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices.  Br. J. Pharmacol., 117:1457-1462.

4. Chittajallu R, Vignes M, Dev KK, Barnes JM, Collingridge GL and Henley JM (1996)  Regulation of glutamate release by presynaptic kainate receptors in the hippocampus.  Nature, 379:78-81.

3. Harvey J, Palmer MJ, Irving AJ, Clarke VRJ and Collingridge GL (1996) NMDA receptor dependence of mGlu-mediated depression of synaptic transmission in the CA1 region of the rat hippocampus. Br. J. Pharmacol., 119:1239-1247.

 

 

1995   LTP Program

2. Bushell TJ, Jane DE, Tse HW, Watkins JC, Davies CH, Garthwaite J and Collingridge GL (1995) Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. Neuropharmacol., 34:.239-241.

1. Vignes M, Clarke VRJ, Davies CH, Chambers A, Jane DE, Watkins JC and Collingridge GL (1995) Pharmacological evidence for an involvement of group-II and group-III mGlurs in the presynaptic regulation of excitatory synaptic responses in the ca1 region of rat hippocampal slices. Neuropharmacol., 34:973-982.